Southwest Houston Romantic Holidays 2026

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Top Romantic Southwest Houston Hotels

Hotel Granduca Houston

1080 Uptown Park Blvd Houston TX

9 min drive from MD Anderson Cancer Center

Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...

9.2/10 Wonderful! (1,001 reviews)

"Room was very big and nice. Very clean and very good arranged. Hotel is beautiful and pool was very good. Lunch at restaurant was tasty. Service at hotel everywhere was excellent. Thanks"

Reviewed on 30 Sept 2026

The Greenleigh, River Oaks, Autograph Collection

2525 West Loop S Houston TX

6 min drive from MD Anderson Cancer Center

Stay at this hotel in Houston. Enjoy free Wi-Fi, room service and valet parking (surcharge). Our guests praise the clean rooms in their reviews. Popular attractions ...

Omni Houston Hotel

4 Riverway Houston TX

9 min drive from MD Anderson Cancer Center

Stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa and 3 bars/lounges. Our guests praise the helpful staff in their reviews. Popular ...

See all 1,285 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.