Photo by Southernmost Illinois Tourism Bureau

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Top Pet-friendly Southwest Illinois Hotels

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

5.8/10 (1,002 reviews)

The hotel and surrounding area was quiet with great restaurants and shopping nearby.

Reviewed on 27 Dec 2025

Red Roof Inn St Louis - Troy, IL

2030 Formosa Road Troy IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their ...

7.6/10 Good! (1,001 reviews)

Would have liked a better variety for breakfast but overall stay was great.

Reviewed on 25 Nov 2025

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

6 Gateway Dr Collinsville IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.2/10 Good! (1,002 reviews)

Staff

Reviewed on 22 Dec 2025

See all 732 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.