Southeast Jacksonville Adventure Holidays 2026

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Top Adventure Southeast Jacksonville Hotels

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful ...

8.4/10 Very good! (729 reviews)

"Great stay! We will be happy to stay again😄"

Reviewed on 20 Sept 2026

Residence Inn by Marriott Jacksonville Butler Boulevard

10551 Deerwood Park Blvd Jacksonville FL

7 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff and the clean ...

Marriott Jacksonville

4670 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...

See all 602 properties in Southeast Jacksonville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.