Midtown Travel Guide
Tourist Guide
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Climb to the very top of America’s tallest man-made structure for sweeping views across the city of St. Louis and the surrounding countryside.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
A Taste of Two Cities: Food and History Tour of Saint Louis
Our pick of the best Midtown Hotel Deals
Residence Inn by Marriott St Louis Downtown
Upon check in I didn’t realize it was a gated parking lot, so I had to pay an extra $30 for 1 day of parking. They also charge a $50 deposit at check in as well. I already spent almost 200 a night to stay for one night so an extra $80 I wasn’t happy about. The beds also weren’t as comfy as they could ...
Reviewed on 11 May 2026
Element St. Louis Midtown
We love this hotel. We stay there every trip to St. Louis. Never disappointed!
Reviewed on 12 May 2026
Hyatt Regency St. Louis at The Arch
Good location, staff didn't seem to know the area well. Room was clean. Elevators seemed to need serviced.
Reviewed on 16 May 2026
Hollywood Casino & Hotel St. Louis
Clean Rooms excellent environment
Reviewed on 14 May 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Room felt dirty, old bed bug shells, ac didn’t work
Reviewed on 15 May 2026
Pear Tree Inn St. Louis Near Union Station
The only thing I could have a negative comment on was the bathroom was tiny and the vanity tiny also. But the people were so kind and friendly. Overall a good experience.
Reviewed on 15 May 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
