Midtown Hotels, St. Louis
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Our top choices for Midtown hotels
Element St. Louis Midtown
Element St. Louis MidtownMidtown
9.0 out of 10, Wonderful, (668 reviews)
"Staff was amazing and hotel was super clean. Great locations with easy access. Valet was fast and took great care of us. "
Kyle
Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis DowntownMidtown
7.8 out of 10, Good, (1,002 reviews)
"All good"
Christopher-Joi
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa27.1 km from Midtown
8.4 out of 10, Very good, (1,006 reviews)
"The room was great. I enjoyed my stay. "
Wanda
Fairfield Inn & Suites by Marriott St. Louis Downtown
Fairfield Inn & Suites by Marriott St. Louis DowntownDowntown West, 1.3 km from Midtown
9.2 out of 10, Wonderful, (1,004 reviews)
"Breakfast was not good at all but the rooms were clean and there was easy parking"
Elizabeth
Moonrise Hotel
Moonrise Hotel6.8 km from Midtown
9.0 out of 10, Wonderful, (1,921 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
Jaden
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hampton Inn St. Louis-Downtown (At the Gateway Arch)Downtown St. Louis, 3.5 km from Midtown
8.8 out of 10, Excellent, (1,218 reviews)
"friendly helpful staff, clean comfy room"
Lisa
Courtyard by Marriott St. Louis Downtown/Convention Center
Courtyard by Marriott St. Louis Downtown/Convention CenterDowntown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1,002 reviews)
"Very clean rooms and very friendly, helpful staff "
Emily
Hilton Pennywell St. Louis at the Arch
Hilton Pennywell St. Louis at the ArchDowntown St. Louis, 3.4 km from Midtown
8.8 out of 10, Excellent, (1,035 reviews)
"Always a pleasure to stay there it’s one of my favorite places in St. Louis.
"
Dorris
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham23.2 km from Midtown
8.0 out of 10, Very good, (1,095 reviews)
"Great room, great people, great breakfast "
Jaiden
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District27.4 km from Midtown
9.4 out of 10, Exceptional, (1,002 reviews)
"Wonderful place staff awesome "
Chad
The Knight Center at Washington University
The Knight Center at Washington University7.7 km from Midtown
9.4 out of 10, Exceptional, (475 reviews)
"Great place to stay, friendly staff, nice room, bathroom, and TV. "
Natalie
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the ArchDowntown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3,328 reviews)
"Nice staff, clean rooms, dinner and breakfast for quests. "
Brad
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio HotelDowntown St. Louis, 3 km from Midtown
8.8 out of 10, Excellent, (1,230 reviews)
"Wonderful stay"
David
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay9.8 km from Midtown
8.8 out of 10, Excellent, (3,089 reviews)
"The price was amazing for the great service and stay. Definitely would stay again!"
Regan
Casino Queen Hotel
Casino Queen Hotel4.5 km from Midtown
7.8 out of 10, Good, (2,008 reviews)
"Yes it was a great stay"
Suzy
Embassy Suites by Hilton St. Louis Downtown
Embassy Suites by Hilton St. Louis DowntownDowntown St. Louis, 3.1 km from Midtown
8.8 out of 10, Excellent, (1,285 reviews)
"Clean room, great breakfast, perfect location."
Kevin
Courtyard by Marriott St. Louis Brentwood
Courtyard by Marriott St. Louis Brentwood9.3 km from Midtown
9.4 out of 10, Exceptional, (868 reviews)
"We always enjoy our stay here nice clean and great location "
Dominique
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The ArchDowntown St. Louis, 3.4 km from Midtown
8.4 out of 10, Very good, (4,019 reviews)
"Nice room & friendly staff!"
Cynthia
Hampton Inn St. Louis/Chesterfield
Hampton Inn St. Louis/Chesterfield29.1 km from Midtown
8.6 out of 10, Excellent, (1,001 reviews)
"Friendly staff"
Gary
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO27.6 km from Midtown
8.6 out of 10, Excellent, (792 reviews)
"Clean, great breakfast options."
Kristy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Midtown
Find the best Midtown areas for the activities you enjoy most.
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
Photo by Terry Eaves
Open Photo by Terry Eaves
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Top Midtown Hotel Reviews
Hollywood Casino & Hotel St. Louis
10/10 Excellent
