Midtown Travel Guide
Tourist Guide
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.
Gateway Arch
Climb to the very top of America’s tallest man-made structure for sweeping views across the city of St. Louis and the surrounding countryside.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St. Louis Premium Small Group Tour With Arch & River Cruise
Gateway Arch National Park Self Guided Audio Walking Tour
Our pick of the best Midtown Hotel Deals
Element St. Louis Midtown
For the price I paid, I feel the breakfast selection wasn’t the greatest, however everything served was fresh. Also, I paid an extra 80 plus dollars for parking. If it was mentioned in the listing, it wasn’t plain text that parking was extra. I understand parking space in a big city is a premium, ...
Reviewed on 30 Mar 2026
Residence Inn by Marriott St Louis Downtown
Was not able to use the pool and that was my reasoning for booking the hotel room.
Reviewed on 28 Mar 2026
Drury Plaza Hotel St. Louis at the Arch
The breakfast food was not very good. The breakfast area was kind of dirty. There were probably a couple of hundred people going through there touching the tongs, but there was not a single hand sanitizer to be found. And this was at the height of flu season. Pretty gross.
Reviewed on 28 Mar 2026
Pear Tree Inn St. Louis Near Union Station
Room was clean, pool was nice and breakfast had a great variety of foods to choose.
Reviewed on 30 Mar 2026
Clayton Plaza Hotel & Extended Stay
I did not eat breakfast but it’s was an amazing stay.
Reviewed on 30 Mar 2026
21C Museum Hotel St Louis
We never got to check in lol. At 1830 they still has no rooms clean. Large line waiting. We just canceled and left 😩
Reviewed on 30 Mar 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
