A calm lake surrounded by trees and vegetation.

Spa Hotels & Resorts in Southwest Illinois from NZ$199

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Spa Hotels

Tonight
15 Aug - 16 Aug
Tomorrow
16 Aug - 17 Aug
Next weekend
21 Aug - 23 Aug
In two weeks
28 Aug - 30 Aug

Our top choices for Southwest Illinois hotels with a spa

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
NZ$224
includes taxes & fees
16 Aug - 17 Aug
Walker's Bluff Casino Resort

2. Truitt Hotel

Truitt Hotel
Lafayette Square
NZ$386
includes taxes & fees
16 Aug - 17 Aug
Truitt Hotel

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
NZ$199
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NZ$323
includes taxes & fees
7 Sept - 8 Sept
Ameristar Casino Resort and Spa

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NZ$294
includes taxes & fees
6 Sept - 7 Sept
21C Museum Hotel St Louis

6. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NZ$744
includes taxes & fees
16 Aug - 17 Aug
Four Seasons Hotel St Louis

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NZ$1,266
includes taxes & fees
24 Aug - 25 Aug
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in Southwest Illinois

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Spacious & very well maintained rooms. Check in went smoothly. Good assortment of food for breakfast & staff very accommodating. Will definitely recommend hotel."
Angela 1-night trip
Posted less than an hour ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"It was great. The breakfast was also great."
Tamara 1-night trip
Posted 11 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Good place after a long day. Good breakfast. Clean and quiet."
Ken 1-night trip
Posted 16 hours ago
Drury Inn & Suites Marion
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Comfortable clean room with nice hot tub. Breakfast had many options and fresh fruits. Suppers offered were mediocre but if you didn’t want to go out they would suffice. A couple great restaurants in the area. Staff were helpful and available! Would definitely stay there again!"
Deborah 2-night trip
Posted 22 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"our room was good sized with a comfortable bed well maintained and clean"
Gary 1-night trip
Posted 2 days ago
Comfort Suites Mount Vernon

Explore a world of travel with Expedia