A calm lake surrounded by trees and vegetation.

Business Hotels & Resorts in Southwest Illinois from NZ$126

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Check availability on Southwest Illinois Business Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Southwest Illinois business-friendly hotels

A hotel reception desk with a digital display, a desk phone, and a computer. There is a sign indicating the hotel's name and services.

1. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (435 reviews)
"Clean property and friendly staff"
United States
Jo Ann
The price is NZ$173
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

2. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,856 reviews)
"The breakfast was amazing"
United States
Angie
The price is NZ$222
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Mt. Vernon
A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

3. Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (459 reviews)
"Worked well for our short stay."
United States
Steven
The price is NZ$232
includes taxes & fees
3 Nov - 4 Nov
Best Western U. S. Inn
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

4. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (686 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is NZ$276
includes taxes & fees
3 Nov - 4 Nov
Best Western Plus Centralia Hotel & Suites
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

5. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,001 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is NZ$151
includes taxes & fees
1 Dec - 2 Dec
SureStay Hotel by Best Western Whittington Rend Lake
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.

6. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (542 reviews)
"A great place to stay"
United States
Ron
The price is NZ$290
includes taxes & fees
9 Nov - 10 Nov
Walker's Bluff Casino Resort
A hotel lobby with a reception desk, seating area, and a large screen TV.

7. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,094 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is NZ$235
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.

8. Red Bud Country Inn

Red Bud Country Inn
2.5 star property
Red Bud
8.8 out of 10, Excellent, (79 reviews)
"Great value. Clean, spacious room. Minimal continental breakfast; apple juice was past its prime."
United States
James
The price is NZ$173
includes taxes & fees
3 Nov - 4 Nov
Red Bud Country Inn
A covered porch with a metal railing, a red carpet, and a green chair.

9. K-River Motel & Campground

K-River Motel & Campground
2.0 star property
Baldwin
9.0 out of 10, Wonderful, (23 reviews)
"I enjoyed my stay very much. Clean room, comfortable bed, friendly staff and atmosphere. I would recommend this to anyone "
United States
Joyce
The price is NZ$128
includes taxes & fees
3 Nov - 4 Nov
K-River Motel & Campground
A large, two-story house with a wrap-around porch and a central tower.

10. The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (22 reviews)
"A pitch perfect stay"
United States
James
The price is NZ$308
includes taxes & fees
3 Nov - 4 Nov
The Conner House B&B
A hotel room with two beds, a grey armchair, and a wall-mounted lamp.

11. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,003 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is NZ$222
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express & Suites Mount Vernon by IHG
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,007 reviews)
"Staff was very friendly"
United States
Karissa
The price is NZ$210
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites St. Louis O'Fallon, IL
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

13. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (722 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is NZ$145
includes taxes & fees
8 Nov - 9 Nov
Quality Inn Mount Vernon, IL
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

14. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was wonderful and the breakfast was good."
United States
Alice
The price is NZ$204
includes taxes & fees
8 Nov - 9 Nov
Best Western Plus MidAmerica Hotel
A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

15. Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.4 out of 10, Very good, (434 reviews)
"Nice, big building with big, comfy lobby. We were at the end of a long hallway so it was nice and private for us. Woman in charge was very pleasant and competent. Got us checked in right away."
United States
Frederick
The price is NZ$155
includes taxes & fees
15 Nov - 16 Nov
Baymont by Wyndham Chester IL
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.

16. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
2.0 star property
Okawville
7.4 out of 10, Good, (369 reviews)
"Great place to stay on a budget!"
United States
Peter
The price is NZ$126
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Okawville
A Comfort Inn & Suites hotel with a covered entrance, multiple floors, and a landscaped front yard.

17. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean and comfortable room. Breakfast options were very good!"
United States
Suzan
The price is NZ$238
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Marion I-57
A lobby with a sofa, chairs, a fireplace, a clock, and framed pictures on the wall.

18. Fairgrounds Inn

Fairgrounds Inn
2.0 star property
Du Quoin
7.6 out of 10, Good, (447 reviews)
"The establishment is very pleasant. My kids and I enjoyed the indoor swimming pool, and the nice big space in the back of the hotel on there patio. They have two BBQ grills picnic tables at least 5 of them, and just a very"
United States
Kasey
The price is NZ$142
includes taxes & fees
3 Dec - 4 Dec
Fairgrounds Inn
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

19. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (908 reviews)
"Nice clean and great staff"
United States
Kenneth
The price is NZ$256
includes taxes & fees
7 Nov - 8 Nov
DoubleTree by Hilton Mt. Vernon
A stone building with a white porch and a small garden with yellow flowers.

20. Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
Maeystown
9.4 out of 10, Exceptional, (156 reviews)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is NZ$253
includes taxes & fees
5 Nov - 6 Nov
Corner George Inn Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southwest Illinois Hotel Reviews

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Clean, comfortable, safe, breakfast."
Mariah 1-night trip
Posted 20 hours ago
Comfort Inn Edwardsville - St. Louis

Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
Rates for business hotels in Southwest Illinois range between NZ$126 and NZ$232 per night. No matter your budget, Expedia is here to help you find the perfect place for a successful work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southwest Illinois?
When you need to travel for work in Southwest Illinois, you'll have 105 business-friendly hotels to pick from.
What is there to do in Southwest Illinois near my business-friendly hotel?
You'll find many exciting attractions to explore when travelling through Southwest Illinois. If you're planning a few nights in Murphysboro, Lake Murphysboro State Park is a hit with visitors.

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