Business Hotels & Resorts in Southwest Illinois from NZ$114

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Check availability on Southwest Illinois Business Hotels

Our top choices for Southwest Illinois business-friendly hotels

Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,659 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
United States
Christina
The price is NZ$213
includes taxes & fees
22 Mar - 23 Mar
Drury Plaza Hotel Mt. Vernon
Free daily continental breakfast

Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (402 reviews)
"Good staff "
United States
Jose Diego
The price is NZ$160
includes taxes & fees
22 Mar - 23 Mar
Best Western U. S. Inn
Lobby

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (932 reviews)
"Great place to stay."
United States
Stephen
The price is NZ$142
includes taxes & fees
1 Mar - 2 Mar
SureStay Hotel by Best Western Whittington Rend Lake
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,003 reviews)
"All of the above, enjoyed the evening meal and breakfast, also staff was very friendly. "
United States
Barbara
The price is NZ$197
includes taxes & fees
6 Mar - 7 Mar
Drury Inn & Suites Marion
Lobby

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very good, (428 reviews)
"Great place to stay. Friendly front desk staff, comfortable rooms. "
United States
Douglas
The price is NZ$167
includes taxes & fees
8 Mar - 9 Mar
Comfort Inn & Suites Greenville I-70
Lobby

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (819 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
United States
Dianna
The price is NZ$124
includes taxes & fees
22 Feb - 23 Feb
Ramada by Wyndham Vandalia
Exterior

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (524 reviews)
"Yes, very clean and service was great."
United States
allen
The price is NZ$207
includes taxes & fees
26 Feb - 27 Feb
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
In-room safe, desk, iron/ironing board, cots/infant beds

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very good, (1,000 reviews)
"I always stay at this hotel when visiting! Its updated and the staff is so attentive!"
United States
Anessa
The price is NZ$114
includes taxes & fees
26 Feb - 27 Feb
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Reception

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (614 reviews)
"Very beautiful place to stay "
United States
Valerie
The price is NZ$208
includes taxes & fees
22 Mar - 23 Mar
Best Western Plus Centralia Hotel & Suites
Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.6 out of 10, Excellent, (360 reviews)
"The room was clean and the staff were friendly. "
United States
RODNEY
The price is NZ$147
includes taxes & fees
22 Feb - 23 Feb
Baymont by Wyndham Chester IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southwest Illinois Hotel Reviews

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

10/10 Excellent
"I stayed at several hotels in this area and this was the only decent one."
Brian 3-night trip
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
Rates for business hotels in Southwest Illinois range between NZ$114 and NZ$213 per night. No matter your budget, Expedia is here to help you find the perfect place for a successful work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southwest Illinois?
When you need to travel for work in Southwest Illinois, you'll have 105 business-friendly hotels to pick from.
What is there to do in Southwest Illinois near my business-friendly hotel?
You'll find many exciting attractions to explore when travelling through Southwest Illinois. If you're planning a few nights in Murphysboro, Lake Murphysboro State Park is a hit with visitors.

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