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Business Hotels & Resorts in Southeast Missouri

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Check availability on Southeast Missouri Business Hotels

Best Southeast Missouri Business Hotels

Front of property
Echo Bluff State Park

Echo Bluff State Park

2.5 star property
Eminence
9.6 out of 10, Exceptional, (214)
"Beautiful location…excellent service and facilities / grounds were clean and well kept."
United States
William
The price is NZ$261
includes taxes & fees
19 Nov - 20 Nov
Echo Bluff State Park
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1006)
"Very nice stay."
United States
Charity
The price is NZ$179
includes taxes & fees
1 Dec - 2 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (947)
"Delicious, well-ran breakfast and quiet peaceful hotel. "
United States
Janene
The price is NZ$187
includes taxes & fees
23 Nov - 24 Nov
Drury Inn & Suites Poplar Bluff
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
"Clean room, great location and friendly staff"
United States
Mark
The price is NZ$194
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Sikeston, MO
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (463)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is NZ$231
includes taxes & fees
27 Nov - 28 Nov
Courtyard by Marriott Cape Girardeau Downtown
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (687)
"Amazing place"
United States
Mladen
The price is NZ$201
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Poplar Bluff by IHG
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very good, (708)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is NZ$115
includes taxes & fees
19 Nov - 20 Nov
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Children’s play area – outdoor
Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View

3.0 star property
Mountain View
8.6 out of 10, Excellent, (328)
"Staff was very friendly."
United States
Joyce
The price is NZ$177
includes taxes & fees
19 Nov - 20 Nov
Honeysuckle Inn - Mountain View
Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
Perryville
9.2 out of 10, Wonderful, (530)
"Clean room and pleasant staff"
United States
David
The price is NZ$191
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express & Suites Perryville by IHG
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (650)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
The price is NZ$155
includes taxes & fees
19 Nov - 20 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This was a wonderful stay! "
Amanda 2-night trip
Posted 5 days ago
Drury Inn & Suites Sikeston, MO

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Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Prices for business hotels in Southeast Missouri range between and per night. Whatever your budget, Expedia is here to help you find the best place to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southeast Missouri?
When work takes you on the road in Southeast Missouri, there are business-friendly hotels to select from.
What is there to do in Southeast Missouri near my business-friendly hotel?
Whether you're passionate about arts, culture, shopping or dining, Southeast Missouri has something to suit all tastes! The popular city of Cape Girardeau has plenty of things to do, including Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site. If you're planning a business trip to Ste Genevieve, Sainte Genevieve Winery, Bolduc House Museum and Felix Valle House State Historic Site have to be on your itinerary.