Holiday Homes in Southeast Missouri

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Check prices for these dates

Next weekend
1 Aug - 3 Aug
In two weeks
8 Aug - 10 Aug
In one month
22 Aug - 24 Aug
In two months
19 Sept - 21 Sept

Featured Holiday Homes in Southeast Missouri

The Sutton House 2 blocks from Main Street & Courthouse Square
Stunning Victorian-style house with a charming front porch and beautifully manicured lawn.

The Sutton House 2 blocks from Main Street & Courthouse Square

10.0 out of 10, Exceptional, (31)
"Great property, well stocked, very informative about the surrounding area. We enjoyed our stay! "
The price is NZ$375
includes taxes & fees
6 Aug - 7 Aug
The Sutton House 2 blocks from Main Street & Courthouse Square
Unbeatable convenience in amazing Eminence!
Enjoy meals in this cozy dining area with a wooden table and comfortable chairs.

Unbeatable convenience in amazing Eminence!

10.0 out of 10, Exceptional, (9)
Unbeatable convenience in amazing Eminence!
Charming 2-bedroom house with AC, WiFi in serene Van Buren
Kitchen area with a coffee maker, utensils, and mugs.

Charming 2-bedroom house with AC, WiFi in serene Van Buren

2.0 star property
8.6 out of 10, Excellent, (7)
"The place was cozy. Everything worked. The amenities were plenty. We decided to take a day trip, never been to the area and we couldn’t have picked a more perfect place to stay, especially during the busy months you get to avoid the more touristy spots and stay in a very comfortable secluded space."
The price is NZ$268
includes taxes & fees
4 Aug - 5 Aug
Charming 2-bedroom house with AC, WiFi in serene Van Buren
Serenity South -- Gardens, River-Views, and Refreshing Space
Enjoy cooking in this well-equipped kitchen with a refrigerator, microwave, and coffee maker.

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (136)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
The price is NZ$406
includes taxes & fees
25 July - 26 July
Serenity South -- Gardens, River-Views, and Refreshing Space
5-bedroom house just outside of Big Spring-Ozark National Scenic Riverways!
Microwave, oven, stovetop, dishwasher

5-bedroom house just outside of Big Spring-Ozark National Scenic Riverways!

5-bedroom house just outside of Big Spring-Ozark National Scenic Riverways!
5-Bedroom house on Current River
Relax in a serene outdoor space with a table and chairs overlooking a tranquil lake and lush trees.

5-Bedroom house on Current River

10.0 out of 10, Exceptional, (16)
"Very clean property with lots of room. Open concept with wonderful river views from the property length front porch."
5-Bedroom house on Current River
The Loft on the River with Private Gravel bar!!
Situated in a rural setting, this charming building features a gabled roof and a grassy area.

The Loft on the River with Private Gravel bar!!

8.4 out of 10, Very good, (17)
"We had a great time and other than there was no broom so hard to sweep the sand from the beach, but that was very minor. Overall it was clean and we all enjoyed it! Will come back again next year!"
The Loft on the River with Private Gravel bar!!
Clifford's Country Cottage
Enjoy cooking in this kitchen with a stainless steel refrigerator, microwave, and island with a stone countertop.

Clifford's Country Cottage

2.5 star property
10.0 out of 10, Exceptional, (17)
"Sharon was the perfect hostess in a perfect little cottage. Fully stocked kitchen, homemade muffins and bowls of candy. Very comfortable bed. Everything was spotless. Great fire pit area with wood provided. Would definitely stay here again. "
The price is NZ$252
includes taxes & fees
29 July - 30 July
Clifford's Country Cottage
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"
Enjoy cooking in this well-equipped kitchen with a central island, stove, and stainless steel refrigerator.

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

10.0 out of 10, Exceptional, (20)
"Chip was an excellent host, always available to provide tips about restaurants and answer any questions about the property. Property was in great condition and would not hesitate to recommend."
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Relax in this serene bedroom with a large bed, ceiling fan, and TV.

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

7.4 out of 10, Good, (3)
"Enjoyed our stay at Andy’s place! It had everything we needed. Beds were super comfy and the water pressure in the showers was great. Nice, safe location. Easy to get to/from places. Place has a garage which we used one evening during a rain storm but otherwise felt completely safe leaving our vehicle on driveway overnight. We didn’t get a chance to use the nice deck area with bbq grill but this is definitely a great feature of the property. The large tv in the living room was a hit with my...
The price is NZ$422
includes taxes & fees
27 July - 28 July
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Cozy Haven Little Hidden Gem Sleeps 4
Welcome to Our Home, where a friendly reception area awaits with a warm and inviting atmosphere.

Cozy Haven Little Hidden Gem Sleeps 4

9.8 out of 10, Exceptional, (46)
"We loved it! "
The price is NZ$370
includes taxes & fees
28 July - 29 July
Cozy Haven Little Hidden Gem Sleeps 4
Camp Stonebass-Lake House-Hottub
Step up to the Penfield Family Lake House, a charming retreat with a spacious staircase leading to a cozy upper level.

Camp Stonebass-Lake House-Hottub

10.0 out of 10, Exceptional, (2)
"Loved the house! It was exactly as described. Had a great family getaway in such a peaceful and serene setting. Loved the seclusion! Would definitely stay here again!"
Camp Stonebass-Lake House-Hottub
Private lake, beach & hot tub, romantic getaway or family vaca
Enjoy serene views of the lake from this deck.

Private lake, beach & hot tub, romantic getaway or family vaca

10.0 out of 10, Exceptional, (28)
"We had a funeral in Poplar Bluff and needed a place to stay. This worked well for our family for the few days we stayed. "
Private lake, beach & hot tub, romantic getaway or family vaca
Doves Nest Guest House<br> Tranquil & Relaxing
Relax by the fire pit in a serene outdoor space surrounded by a gravel surface and comfortable seating.

Doves Nest Guest House<br> Tranquil & Relaxing

10.0 out of 10, Exceptional, (41)
"Comfortable stay with nice decor and relaxing atmosphere "
The price is NZ$398
includes taxes & fees
27 July - 28 July
Doves Nest Guest House<br> Tranquil & Relaxing
Beautiful 3-bedrm , 3.5 ba Log/Stone in Eminence MO. Will sleep up to 16 guests.
Cozy living area with a stone fireplace, large windows, and a wooden ceiling fan.

Beautiful 3-bedrm , 3.5 ba Log/Stone in Eminence MO. Will sleep up to 16 guests.

10.0 out of 10, Exceptional, (2)
"Our crew stayed here during a float trip and we had a blast! It was the perfect spot for a large group with plenty of space. "
Beautiful 3-bedrm , 3.5 ba Log/Stone in Eminence MO. Will sleep up to 16 guests.
Triple H Properties
Set amidst a serene lawn, this single-story house offers a peaceful retreat.

Triple H Properties

8.6 out of 10, Excellent, (27)
"Lori’s place was a nice spot for a two night stay"
Triple H Properties
"Little Brick House on Main (1865)”
Stunning garden area with potted plants and flowering shrubs, beautifully arranged on wooden stumps and in pots.

"Little Brick House on Main (1865)”

10.0 out of 10, Exceptional, (48)
"The property is a lovely little house, close to places to eat and attractions. "
The price is NZ$263
includes taxes & fees
30 July - 31 July
"Little Brick House on Main (1865)”
Your home away from home in downtown, historic Farmington!
Guests can sit on the riverbank surrounded by lush greenery.

Your home away from home in downtown, historic Farmington!

10.0 out of 10, Exceptional, (29)
"Super clean, well equipped kitchen, quick response to messages. Would definitely stay again. "
The price is NZ$345
includes taxes & fees
27 July - 28 July
Your home away from home in downtown, historic Farmington!
Charming 1860s Renovated Home
Enjoy cooking in this well-equipped kitchen with a stainless steel range hood, microwave, and double oven.

Charming 1860s Renovated Home

8.0 out of 10, Very good, (16)
"Had a great stay"
The price is NZ$547
includes taxes & fees
7 Aug - 8 Aug
Charming 1860s Renovated Home
Family sized barndominium. Sleeps up to 10 comfortably.
Guests enter through a welcoming entrance with a covered patio area and a bench for relaxation.

Family sized barndominium. Sleeps up to 10 comfortably.

10.0 out of 10, Exceptional, (6)
"The property is very nice. All the extras the hostess has at this property is above and beyond any other place I have ever seen. We enjoyed our time there and will definitely be back. "
Family sized barndominium. Sleeps up to 10 comfortably.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"We had a wonderful stay. The room.was clean and comfortable. The pool was far better than most although seasonal. "
Alexander 1-night trip
Posted 1 day ago
Baymont Inn and Suites by Wyndham Farmington, MO