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Our top choices for Seneca hotels

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (214 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is NZ$235
includes taxes & fees
22 Apr - 23 Apr
Fairfield Inn & Suites Seneca Clemson Univ Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,010 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is NZ$232
includes taxes & fees
13 Apr - 14 Apr
Lakeside Lodge Clemson

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (692 reviews)
"Room was very clean, the grounds was in well taken care of, was safe. Overall a good place to stay."
United States
Billy
The price is NZ$174
includes taxes & fees
29 Apr - 30 Apr
Quality Inn Seneca Clemson Area US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (736 reviews)
"Our stay was ok..the bathroom was in need of renovation "
United States
clyde
The price is NZ$138
includes taxes & fees
14 Apr - 15 Apr
Days Inn by Wyndham Seneca / Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (822 reviews)
"Nice clean hotel with several food options available nearby."
United States
kelsey
The price is NZ$234
includes taxes & fees
12 Apr - 13 Apr
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (692 reviews)
"Everything was great. "
United States
Wendy
The price is NZ$232
includes taxes & fees
16 Apr - 17 Apr
Hampton Inn & Suites Seneca-Clemson Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (68 reviews)
"Excellent stay."
United States
Beonca
The price is NZ$262
includes taxes & fees
19 Apr - 20 Apr
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (654 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is NZ$168
includes taxes & fees
26 Apr - 27 Apr
Best Western Seneca-Clemson

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is NZ$667
includes taxes & fees
3 May - 4 May
8 Mi to Clemson: Peaceful Family Home w/ Yard

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,003 reviews)
"Good stay and breakfast"
United States
Jeff
The price is NZ$208
includes taxes & fees
29 Apr - 30 Apr
Best Western Plus Clemson Hotel & Conference Center

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (234 reviews)
"Room was great and the staff polite and helpful "
United States
Sheila D
The price is NZ$302
includes taxes & fees
12 Apr - 13 Apr
Home2 Suites by Hilton Anderson Downtown

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (607 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is NZ$209
includes taxes & fees
3 May - 4 May
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (832 reviews)
"Staff were so helpful , place was clean and food spots near by"
United States
osiry
The price is NZ$221
includes taxes & fees
22 Apr - 23 Apr
Hampton Inn Anderson/ Alliance Business Park

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,009 reviews)
"Awesome place "
United States
Tramaness
The price is NZ$113
includes taxes & fees
28 Apr - 29 Apr
Days Inn by Wyndham Anderson

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (800 reviews)
"Fantastic place and staff most accommodating "
United States
Walter
The price is NZ$119
includes taxes & fees
12 Apr - 13 Apr
Baymont by Wyndham Easley/Greenville

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (365 reviews)
"Great stay"
United States
Annmargaret
The price is NZ$234
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn Hartwell

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (828 reviews)
"Great location, great staff - loved the room! "
United States
Eric
The price is NZ$302
includes taxes & fees
12 Apr - 13 Apr
The Inn at Patrick Square

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (911 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is NZ$110
includes taxes & fees
28 Apr - 29 Apr
Quality Inn Clemson near University

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
Walhalla
7.6 out of 10, Good, (179 reviews)
"Staff was friendly. Check-in was quick, and the rooms were tidy, and the beds were comfortable."
United States
Paula
The price is NZ$133
includes taxes & fees
12 Apr - 13 Apr
Rodeway Inn & Suites Walhalla

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very good, (1,001 reviews)
"Great place to stay. Great foods around. Excellent customer service."
United States
Lucero
The price is NZ$160
includes taxes & fees
19 Apr - 20 Apr
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap accommodation in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 15-minute walk from Clemson University, and it offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade/games room. Some other homes for rent in Seneca include Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Quality Inn Seneca Clemson Area US-123 and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Offers free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Hampton Inn & Suites Seneca-Clemson Area and Quality Inn Seneca Clemson Area US-123 are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 304 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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