Search Seneca hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Seneca

Our top choices for Seneca hotels

Postcard Cabins Lake Hartwell

2.0 star property
9.8 out of 10, Exceptional, (24)
"Lovely stay! Highly recommend!!!"
The price is NZ$233
includes taxes & fees
26 Aug - 27 Aug
Postcard Cabins Lake Hartwell

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (999)
"Great place to stay in Clemson"
The price is NZ$233
includes taxes & fees
28 Aug - 29 Aug
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (186)
"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "
The price is NZ$242
includes taxes & fees
1 Sept - 2 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (629)
"The staff were very friendly and helpful. The room was clean and the breakfast was great!"
The price is NZ$236
includes taxes & fees
27 Aug - 28 Aug
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (693)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is NZ$134
includes taxes & fees
8 Sept - 9 Sept
Days Inn by Wyndham Seneca / Clemson Area

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very good, (632)
"Ok hotel for a quick stay "
The price is NZ$167
includes taxes & fees
31 Aug - 1 Sept
Quality Inn Seneca Clemson Area US-123

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very good, (601)
"We liked the location. It was easy to explore Lake Keowee from here. The blackout window shades were nice too! The room was so humid that it even made the sheets feel damp. "
The price is NZ$190
includes taxes & fees
7 Sept - 8 Sept
Best Western Seneca-Clemson

Woodspring Suites Anderson North I-85

2.5 star property
6.6 out of 10, (23)
"Very nice and clean property. Staff was so nice and helpful. Made check in so easy"
The price is NZ$159
includes taxes & fees
26 Aug - 27 Aug
Woodspring Suites Anderson North I-85

Inn @ Clemson

2.5 star property
8.0 out of 10, Very good, (1004)
"This hotel was a great value. The staff was really helpful and friendly"
The price is NZ$167
includes taxes & fees
1 Sept - 2 Sept
Inn @ Clemson

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very good, (1008)
"Great stay!!"
The price is NZ$191
includes taxes & fees
26 Aug - 27 Aug
Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very good, (1006)
"Awesome place to stay"
The price is NZ$191
includes taxes & fees
13 Sept - 14 Sept
Comfort Inn & Suites Clemson - University Area

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (863)
"Great customer service "
The price is NZ$112
includes taxes & fees
1 Sept - 2 Sept
Quality Inn Clemson near University

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (812)
"Excellent stay "
The price is NZ$129
includes taxes & fees
12 Sept - 13 Sept
Baymont by Wyndham Anderson Clemson

Days Inn by Wyndham Anderson

2.0 star property
7.4 out of 10, Good, (1003)
"Great located "
The price is NZ$114
includes taxes & fees
27 Aug - 28 Aug
Days Inn by Wyndham Anderson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.2 out of 10, Wonderful, (561)
"Clean, convenient, safe. Beds are comfortable. For the rate charged this place offers everything that’s important to me in a hotel stay. Definitely would stay here again. "
The price is NZ$195
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (667)
"Fantastic high-end hotel with great amenities, service and convenience!"
The price is NZ$339
includes taxes & fees
1 Sept - 2 Sept
The Shepherd Hotel Downtown Clemson

Comfort Suites Anderson-Clemson

2.5 star property
8.4 out of 10, Very good, (995)
"RESTAURANTS, HOTEL WAS GREAT STAFF WAS AWESOME I WOULD DEFINITELY RECOMMEND. "
The price is NZ$211
includes taxes & fees
31 Aug - 1 Sept
Comfort Suites Anderson-Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very good, (1000)
"Great place to stay!"
The price is NZ$159
includes taxes & fees
27 Aug - 28 Aug
Microtel Inn & Suites by Wyndham Anderson/Clemson

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
8.4 out of 10, Very good, (1001)
"It was a good place to stay good people "
The price is NZ$206
includes taxes & fees
3 Sept - 4 Sept
Country Inn & Suites by Radisson, Anderson, SC

Holiday Inn Express & Suites Clemson by IHG

2.5 star property
8.8 out of 10, Excellent, (929)
"It was a very easy and convenient place to stay"
The price is NZ$232
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express & Suites Clemson by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Our guide on where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Downtown

2 out of top 10 points of interest in this area

If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Photo by Cindy Keese
Open Photo by Cindy Keese

Top Seneca Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

What are some of the best holiday rentals that Seneca has to offer?

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. : This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade/games room. Some other homes for rent in Seneca include Large family home with dock on Lake Keowee! and 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.. See all vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

What's the best family accommodation in Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.

What is the top LGBTQ-friendly accommodation in Seneca?

Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.

What's the best dog-friendly hotel in Seneca?

Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Fairfield Inn & Suites Seneca Clemson Univ Area and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.

What is staying in Seneca like?

Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 287 hotels and other accommodation options to choose from. Find out more about Seneca.

What should I see while I'm in Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.

What's the seasonal weather in Seneca?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.