Search Santee hotels

The best area to stay in Santee is the area directly off Interstate 95, particularly around the Santee National Wildlife Refuge.


This area is the main visitor hub in Santee. You'll find a concentration of accommodation options, restaurants, and shops conveniently located near the interstate exits. It's a practical and straightforward layout, making it easy to navigate.


For travellers interested in outdoor activities and nature, this location is ideal. The Santee National Wildlife Refuge, a significant natural landmark, is easily accessible, offering opportunities for birdwatching, hiking, and exploring the local ecosystem. Many hotels in this area cater to guests looking for comfortable stays after a day of outdoor adventures.


Golf enthusiasts will also find this area particularly convenient. Several much-loved golf courses are situated within a short drive, making it simple to get to and from the greens.

For highly-rated hotels in Santee, travellers frequently recommend the Best Western Plus Santee Inn and the Comfort Inn & Suites Santee, amongst others.


The Holiday Inn Santee by IHG, with an 8.2 rating, offers comfortable and quiet rooms, with guests often praising the friendly and helpful staff. For those interested in golf, the hotel has a golf course nearby and offers golf caddies, carts, and advance notice for golf games. There is also an indoor pool and room service available.


The Best Western Plus Santee Inn, rated 8.8, is known for its nice, clean rooms and comfortable beds. Guests frequently mention the delicious free breakfast and good amenities, including a private indoor hot tub and an outdoor pool. The front desk staff are also noted for being very helpful. Santee State Park is approximately 5.2 km away.


Another excellent choice is the Comfort Inn & Suites Santee, which has an 8.0 rating. This hotel provides spacious suites, connecting rooms, and free cribs for families. Guests particularly appreciate the hot and good free buffet breakfast. The rooms are consistently described as nice and clean, and the staff are friendly. Santee State Park is just 4.7 km from the hotel.


Finally, the Baymont by Wyndham Santee, with an 8.0 rating, offers nice, clean rooms with comfortable beds, and guests often highlight the great price. A free continental breakfast is provided, and the staff are consistently described as nice and amazing. Santee State Park is approximately 4.8 km away.

For excellent family-friendly hotels in Santee, consider the Fairfield Inn & Suites by Marriott Santee or the Hampton Inn Santee-I-95.


The Fairfield Inn & Suites by Marriott Santee, with an outstanding 9.8 rating, is a superb choice for families. Guests consistently highlight the comfortable and clean rooms, the excellent and friendly staff, and the great complimentary breakfast. The hotel also offers a pool, sofa beds, and provides both cribs and highchairs for children, ensuring a comfortable stay for all family members. It is conveniently located just 5.3 km from Santee State Park.


Another highly recommended option is the Hampton Inn Santee-I-95, which boasts a 9.6 rating. This hotel is praised for its friendly and helpful staff, comfortable and clean rooms, and delicious complimentary breakfast. Amenities suitable for families include a pool, sofa beds, and free cribs and rollaway beds. It is also situated 5.3 km from Santee State Park.

Several hotels in Santee offer a complimentary breakfast, including the Fairfield Inn & Suites by Marriott Santee, Hampton Inn Santee-I-95, Tru By Hilton Santee, Best Western Plus Santee Inn, and Baymont by Wyndham Santee.


The 9.8-rated Fairfield Inn & Suites by Marriott Santee provides a free buffet breakfast, and guests often mention the excellent and friendly staff, comfortable and clean rooms, and the great breakfast. Free self-parking and free WiFi are also available.


Hampton Inn Santee-I-95, with a 9.6 rating, offers a free breakfast that guests describe as delicious. The staff are frequently praised for being friendly and helpful, and the rooms are noted as comfortable and clean. This hotel also provides free WiFi and free self-parking.


Tru By Hilton Santee, rated 9.2, includes a free buffet breakfast. Guests appreciate the nice and clean rooms, as well as the friendly and helpful staff. Free self-parking and free WiFi are among its amenities.


The 8.8-rated Best Western Plus Santee Inn offers a complimentary breakfast, with guests specifically highlighting the free continental breakfast as delicious. The rooms are described as nice and clean, and the beds are comfortable. Free self-parking and free WiFi are also provided.


Baymont by Wyndham Santee, with an 8.0 rating, also includes a free continental breakfast. Guests frequently mention the nice and clean rooms and the amazing staff. Free self-parking and free WiFi are available.

For top pet-friendly hotels in Santee, consider the Fairfield Inn & Suites by Marriott Santee, the Holiday Inn Santee by IHG, the Red Roof Inn Santee, the Best Western Plus Santee Inn, and the Quality Inn & Suites.


The Fairfield Inn & Suites by Marriott Santee, with an excellent 9.8 rating, is highly praised by guests for its comfortable and clean rooms, great breakfast, and excellent staff. This hotel permits both dogs and cats and provides a dedicated dog exercise area, making it very convenient for pet owners. It is located just 5.3 km from Santee State Park.


The Holiday Inn Santee by IHG, rated 8.2, welcomes both dogs and cats. Guests frequently mention the clean and quiet rooms, friendly and helpful staff, and super comfortable beds. There is also a nice bar on site, and the hotel is 4.7 km from Santee State Park.


The Red Roof Inn Santee permits both dogs and cats and is known for its great price. It is conveniently located 4.6 km from Santee State Park.


The Best Western Plus Santee Inn, with an 8.8 rating, is another excellent choice for pet owners, permitting both dogs and cats and offering a dog exercise area. Guests appreciate the nice, clean rooms, comfortable beds, and the delicious free continental breakfast. The helpful front desk staff also receives positive mentions. It is 5.2 km from Santee State Park.


The Quality Inn & Suites permits both dogs and cats and provides a free full breakfast. Guests often praise its great location, nice rooms, and good amenities. It is situated 4.5 km from Santee State Park.

For budget-friendly accommodation in Santee, consider the Fairfield Inn & Suites by Marriott Santee or the Baymont by Wyndham Santee.


The Fairfield Inn & Suites by Marriott Santee, with an impressive 9.8 rating, offers guests a comfortable stay with excellent amenities. Guests frequently praise the friendly and helpful staff, the clean and comfortable rooms, and the great free buffet breakfast. It is conveniently located approximately 5.3 km from Santee State Park.


Another good option is the Baymont by Wyndham Santee, which has a rating of 8.0. This hotel provides a complimentary continental breakfast, free WiFi, and free parking for cars, RVs, buses, and trucks. Its rooms are described as nice and clean, and the staff are often highlighted as amazing. Santee State Park is around 4.8 km away.

For a romantic stay in Santee, couples should consider the Best Western Plus Santee Inn or the Waterfront Condo on Lake Marion.


The Best Western Plus Santee Inn, with an 8.8 rating, offers premium rooms that guests describe as nice and clean. It provides a complimentary continental breakfast, and couples can enjoy the added luxury of a private indoor hot tub. The hotel is conveniently located just 0.1 km from Santee Cooper Country Club.


Another excellent option is the Waterfront Condo on Lake Marion, which boasts a superb 10.0 rating. This accommodation provides stunning water views and features a fully equipped kitchen, a deck or patio, and access to golf facilities both onsite and nearby. It is situated 1.5 km from Santee Cooper Country Club.

For hotels in Santee near Santee State Park, the Fairfield Inn & Suites by Marriott Santee and the Hampton Inn Santee-I-95 are both excellent choices.


The Fairfield Inn & Suites by Marriott Santee has an outstanding 9.8 rating and is located 5.3 km from Santee State Park. Guests frequently praise the excellent and friendly staff, comfortable and clean rooms, and the great free buffet breakfast. This hotel also offers a pool, sofa beds, and cribs, making it very suitable for families.


Another highly-rated option is the Hampton Inn Santee-I-95, with a 9.6 rating, also 5.3 km from Santee State Park. Travellers appreciate the friendly and helpful staff, comfortable and clean rooms, and delicious free breakfast. The hotel provides free WiFi, a pool, and free parking for RVs, buses, or trucks, along with complimentary cribs and rollaway beds.


The Tru By Hilton Santee, with a 9.2 rating and located 4.8 km from Santee State Park, is another strong contender. Guests praise the nice and clean rooms, friendly and helpful staff, and excellent free buffet breakfast. Free toiletries and self-parking are also provided.


The Best Western Plus Santee Inn, rated 8.8 and 5.2 km from Santee State Park, offers nice and clean rooms with super comfortable beds. Guests enjoy the free delicious continental breakfast and the helpful front desk. It also features a pool, connecting rooms, and free self-parking.


Finally, the Holiday Inn Santee by IHG, with an 8.2 rating and 4.7 km from Santee State Park, provides clean and quiet rooms with super comfortable beds. Guests highlight the friendly and helpful staff, and the nice bar. Free cribs, a pool, and free WiFi are available.

The best time to visit Santee is during the spring (March to May) and autumn (September to November) months.


These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity, which is ideal for enjoying outdoor activities such as golfing, fishing, and exploring the natural beauty of Lake Marion and the surrounding areas. You'll find it's not too hot for a round of golf, nor too chilly for a boat trip.


For those planning a golf trip, these periods are particularly good as the courses are in excellent condition, and the weather allows for extended play without the intense heat of summer. You'll have a more enjoyable and relaxed time on the greens.


Families looking for a getaway will also appreciate these times of year.

You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to ‘My Trips’ and selecting your reservation. To find flexible deals, filter your search by ‘Fully refundable property’ for hotels in Santee.

One Key™—Expedia’s free travel rewards programme—gives you instant access to discounts with Member Prices on Santee hotels. Plus, you’ll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Prices for hotels in Santee often vary, but you can find a great deal from NZ$118 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by ‘Price: low to high’ for our cheapest rates.