Santee Holiday Rentals

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Our top choices for Santee holiday rentals

10.0 out of 10, Exceptional, (37)
"Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. "
United States
John H.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
8.4 out of 10, Very good, (6)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
The price is NZ$342
includes taxes & fees
3 Jan - 4 Jan 2026
Tranquil Getaways W/Heated Pool and Fishing
10.0 out of 10, Exceptional, (11)
"Nice place great location "
United States
Jeffrey H.
The price is NZ$843
includes taxes & fees
14 Jan - 15 Jan 2026
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
10.0 out of 10, Exceptional, (40)
"Great stay."
United States
Tim E.
The price is NZ$366
includes taxes & fees
2 Jan - 3 Jan 2026
Country living lake style near Santee
9.4 out of 10, Exceptional, (21)
"Great place for our family to stop on our way to Florida. It had ample parking, pet friendly, and very comfortable country retreat! "
United States
Jackie M.
The price is NZ$320
includes taxes & fees
14 Jan - 15 Jan 2026
Country Resting Spot just off I95. 12 miles west on hwy 6.

Mobile Home in Summerton

Hobbs Haven at Lake Marion
9.4 out of 10, Exceptional, (11)
"Everything was great!"
United States
James B.
The price is NZ$613
includes taxes & fees
3 Jan - 4 Jan 2026
Hobbs Haven at Lake Marion

Aparthotel in Eutawville

Bells Marina & Resort
2.5 star property
8.6 out of 10, Excellent, (82)
"Room was clean with a beautiful view of the Lake."
United States
Melanie
The price is NZ$185
includes taxes & fees
6 Jan - 7 Jan 2026
Bells Marina & Resort
9.8 out of 10, Exceptional, (16)
"Great stay!! "
United States
Josh L.
The price is NZ$293
includes taxes & fees
5 Jan - 6 Jan 2026
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
9.8 out of 10, Exceptional, (32)
"Will stay again."
United States
Robert B.
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
10.0 out of 10, Exceptional, (124)
"Super cute little house. Super comfy beds and pretty views. "
United States
colleen j.
The price is NZ$358
includes taxes & fees
12 Jan - 13 Jan 2026
Pet friendly country cottage with large fenced-in yard & horses on property
7.8 out of 10, Good, (7)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is NZ$245
includes taxes & fees
1 Jan - 2 Jan 2026
Cabin at the lake in Rimini, SC
10.0 out of 10, Exceptional, (6)
"Excellent stay! We will definitely be staying here again! Love this place! "
United States
Jonathan H.
The price is NZ$277
includes taxes & fees
31 Jan - 1 Feb 2026
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
8.2 out of 10, Very good, (14)
"Wish bathroom was closer but jt"
United States
Sharon W.
The price is NZ$229
includes taxes & fees
1 Jan - 2 Jan 2026
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cottage in Shad Moss village

Cypress Cottage - Cozy Lake Getaway
2.0 star property
The price is NZ$511
includes taxes & fees
4 Jan - 5 Jan 2026
Cypress Cottage - Cozy Lake Getaway
The price is NZ$538
includes taxes & fees
6 Jan - 7 Jan 2026
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton
8.6 out of 10, Excellent, (18)
"Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay."
United States
Chris D.
The price is NZ$806
includes taxes & fees
4 Jan - 5 Jan 2026
Sweet Marion - Dock + Boat Ramp + Hot Tub!
9.0 out of 10, Wonderful, (4)
"Nice and quiet property. It served us well for the weekend "
United States
Mick S.
The price is NZ$484
includes taxes & fees
1 Jan - 2 Jan 2026
Beautiful brick home w/ large porch and 3 bedrooms
6.8 out of 10, (5)
"Perfect place for a weekend fishing trip. Owner was responsive. Slept 6 easily. Only stayed one night but was a perfect fit"
United States
brandon h.
The price is NZ$717
includes taxes & fees
5 Jan - 6 Jan 2026
Reel Haven on the Water: Modern + Comfy Home!
The price is NZ$735
includes taxes & fees
1 Jan - 2 Jan 2026
Turtle Cove - Lake Living on Lake Marion
The price is NZ$460
includes taxes & fees
14 Jan - 15 Jan 2026
The Tee Vee Cove is the place to be located near great golfing, fishing and food
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santee holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santee holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santee holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santee holiday rentals we have selected for you start as low as NZ$185 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in Santee?

Yes, there are holiday rentals close to the most popular sights in Santee, or you can select a more secluded option if you're looking for a relaxing stay. Tourists appreciate the top-notch restaurants and coffee shops in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best holiday rentals that Santee has to offer?

Wyndham Vacation Resorts Lake Marion: This highly rated holiday home rental in Santee is equipped with an outdoor pool, free WiFi and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher and a stovetop. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many holiday rentals are there in Santee?

Expedia has 9 holiday rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are holiday rentals like in Santee?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santee. Holiday rentals feature amenities like kitchens and laundry facilities so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can provide a sense of security away from public hotel lifts and busy reception areas while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great option for small groups.