Search Santee hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santee hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1418)
This peaceful hotel offers complimentary breakfast, WiFi and parking near Santee National Golf Club. Guests consistently praise the quiet atmosphere, comfortable accommodation and helpful staff. The convenient location provides easy access to everything needed.

"Room was very nice and staff was very nice"
United States
Rupert
The price is NZ$145
includes taxes & fees
4 Jan - 5 Jan
Baymont by Wyndham Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1011)
Escape to a tranquil retreat in Santee's entertainment district where helpful staff welcome you. Enjoy the seasonal outdoor pool after exploring nearby Santee Cooper Country Club, then recharge with complimentary breakfast before your next adventure.

"It was quite and comfortable stay"
United States
Shankar
The price is NZ$203
includes taxes & fees
11 Jan - 12 Jan
Comfort Inn & Suites Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is NZ$228
includes taxes & fees
12 Jan - 13 Jan
Best Western Plus Santee Inn

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (662)
Energising Santee hotel with an indoor pool for morning swims and a 24-hour fitness centre. Enjoy free breakfast, WiFi, and parking. Close to Santee Cooper Country Club and Santee National Golf Club. Guests rave about the helpful staff.

"Nice place to stay"
Canada
Tanya
The price is NZ$208
includes taxes & fees
12 Jan - 13 Jan
Tru By Hilton Santee

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (310)
This budget-friendly hotel sits close to Santee Cooper Country Club and Santee National Golf Club. Guests appreciate the convenient amenities including complimentary WiFi, free parking, and 24-hour reception service.

"Last minute arrangements stay was quiet and peaceful "
United States
Iasia
The price is NZ$122
includes taxes & fees
15 Jan - 16 Jan
Econo Lodge Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (460)
Immerse yourself in Southern hospitality at this Quality Inn where 7 restaurants and a seasonal outdoor pool await. Enjoy free breakfast, WiFi and parking while exploring nearby Santee Cooper Country Club. Guests consistently praise the helpful staff and clean accommodation.

"exellent service"
United States
Mirjana
The price is NZ$114
includes taxes & fees
14 Jan - 15 Jan
Quality Inn & Suites Santee I-95

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (685)
This Santee hotel offers daily continental breakfast and complimentary WiFi and parking. Praised for helpful staff and clean rooms, the location provides easy access to Santee Cooper Country Club and Santee National Golf Club.

"Nice quiet room and a delicious breakfast at a reasonable rate."
United States
Joseph B
The price is NZ$118
includes taxes & fees
6 Jan - 7 Jan
Travelodge by Wyndham Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (981)
Adjacent to a golf course, this hotel offers an indoor pool and convenient on-site dining. Guests love the helpful staff and clean rooms. Nearby attractions include Santee Cooper Country Club and Santee National Golf Club, while free WiFi and parking enhance your stay.

"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is NZ$229
includes taxes & fees
7 Jan - 8 Jan
Holiday Inn Santee by IHG

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1002)
"Great place to stop on a road trip! Breakfast was great, pets allowed, friendly staff. "
United States
Stephanie
The price is NZ$259
includes taxes & fees
18 Jan - 19 Jan
Hampton Inn Santee-I-95

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1001)
Set in a peaceful location, this hotel offers free breakfast, WiFi, and parking. Guests can enjoy the outdoor pool or workout at the health club. The helpful staff ensure comfort while Santee Cooper Country Club and Santee National Golf Club are just moments away.

"Clean spacious room, nice amenities and good breakfast. "
United States
Donna
The price is NZ$233
includes taxes & fees
18 Jan - 19 Jan
Fairfield Inn & Suites by Marriott Santee

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (441)
Tranquil accommodation next to Santee Cooper Country Club with a refreshing seasonal outdoor pool. Free perks include daily on-the-go breakfast, WiFi, and parking. Conveniently located near Santee National Golf Club for the perfect golf getaway.

"The staff was very friendly and helpful. Room was clean and beds were so comfortable. "
United States
Kathy
The price is NZ$145
includes taxes & fees
4 Jan - 5 Jan
Super 8 by Wyndham Santee

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (640)
A perfect stopover with free breakfast, parking, and WiFi at this lakeside hotel. Just minutes from Santee Cooper Country Club and offering easy access to water skiing adventures. Modern rooms provide a restful retreat after exploring Santee National Golf Club.

"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is NZ$135
includes taxes & fees
4 Jan - 5 Jan
Red Roof Inn Santee

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (545)
This golf-adjacent hotel offers an outdoor pool with poolside bar, plus a 24-hour fitness centre for active travellers. Rooms include refrigerators and microwaves. Santee Cooper Country Club is nearby, with free WiFi and parking for added convenience.

"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is NZ$152
includes taxes & fees
11 Jan - 12 Jan
Ramada by Wyndham Santee I-95

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (82)
Escape to this waterfront Eutawville aparthotel featuring its own marina on Lake Marion. Play a round of golf, work out at the fitness centre, or dine at the on-site restaurant before exploring Ferguson Island and Round Island nearby.

"Room was clean with a beautiful view of the Lake."
United States
Melanie
The price is NZ$186
includes taxes & fees
6 Jan - 7 Jan
Bells Marina & Resort

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (148)
"Clean rooms and pleasant staff. Could use newer towels. "
United States
Patricia
Peach Tree Inn

Days Inn by Wyndham St George

Days Inn by Wyndham St George
2.5 star property
St. George
7.6 out of 10, Good, (1003)
Conveniently located in a good spot to explore St. George, this hotel offers free continental breakfast, WiFi, and parking. Saint George Public Library is nearby, and guests rave about the clean rooms and attentive staff.

"Very polite staff "
United States
Thomas
The price is NZ$129
includes taxes & fees
18 Jan - 19 Jan
Days Inn by Wyndham St George

Budget Inn By Belvilla St George I-95

Budget Inn By Belvilla St George I-95
2.5 star property
St. George
7.6 out of 10, Good, (160)
This hotel offers convenient highway access, with perks including complimentary WiFi and self parking. The 24-hour front desk ensures assistance anytime. Saint George Public Library and Jennie J McMahan Library are located nearby.

"This is a great value for a budget hotel. It's an older complex but clean and well maintained. It's close to decent food options for tired travelers and the front desk staff was pleasant and helpful. If you are looking for a convient, well priced stopover, I recommend this location. "
United States
Kim
The price is NZ$132
includes taxes & fees
6 Jan - 7 Jan
Budget Inn By Belvilla St George I-95

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1009)
This business-friendly hotel offers free WiFi and full breakfast daily. Clean rooms provide a relaxing atmosphere after exploring Manning. Previous guests highly praise the helpful staff and overall cleanliness.

"For the money, a great option..."
United States
James
The price is NZ$172
includes taxes & fees
1 Feb - 2 Feb
SureStay Hotel by Best Western Manning

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very good, (1001)
Located just a short drive from Charleston International Airport, this hotel offers clean accommodation with premium comfort. Relax at the bar after a workout in the 24-hour fitness centre. Free breakfast, WiFi, and parking enhance your visit.

"The room and lobby was very clean and nicely decorated. Staff was very friendly and helpful."
United States
Carey
The price is NZ$229
includes taxes & fees
26 Jan - 27 Jan
Hampton Inn Manning

Econo Lodge St. George

Econo Lodge St. George
2.0 star property
St. George
6.4 out of 10, (261)
Soak up the sunshine at this welcoming hotel featuring a refreshing seasonal outdoor pool. Conveniently located near Saint George Public Library, guests enjoy free WiFi and parking. The Jennie J McMahan Library is also nearby.

"It was nice all together "
United States
Marcia
The price is NZ$110
includes taxes & fees
15 Jan - 16 Jan
Econo Lodge St. George
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap accommodation in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favourite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveller reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best holiday rentals that Santee has to offer?
Wyndham Vacation Resorts Lake Marion: This highly rated holiday home rental in Santee is equipped with an outdoor pool, free WiFi and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher and a stovetop. Our travellers also rate Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! as a favourite home for rent in Santee. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Tru By Hilton Santee is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Two other good options for you and your pet include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Waterfront Condo on Lake Marion. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 126 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee State Park and Lake Marion. A couple of additional sights to add to your itinerary are Santee National Golf Club and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

Explore a world of travel with Expedia