Santa Maria Hotels, Guayaquil

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Maria hotels

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.4 out of 10, Exceptional, (104 reviews)
"The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions."
United States
Carolyn
The price is NZ$175
12 Feb - 13 Feb
Luxury Suites Riverfront GYE

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana, 7.6 km from Santa Maria
8.8 out of 10, Excellent, (46 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is NZ$133
1 Feb - 2 Feb
River View suites Puerto Santa Ana gye

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 7.8 km from Santa Maria
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is NZ$109
1 Feb - 2 Feb
Mansión del Río

Hostal California Inn

Hostal California Inn
3.0 star property
7.4 km from Santa Maria
8.6 out of 10, Excellent, (8 reviews)
"Me encantó, es muy cómoda, la habitación super amplia y limpia Si duda volveré "
Mexico
Anita
Hostal California Inn

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is NZ$79
1 Feb - 2 Feb
Hotel La Ria Durán

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean rooms,great staff and very good food"
Canada
Abel Patricio
The price is NZ$187
17 Feb - 18 Feb
Wyndham Guayaquil Puerto Santa Ana

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 7.6 km from Santa Maria
The price is NZ$66
1 Feb - 2 Feb
Guayacan Apart Hotel

Murali Hostal Guayaquil

Murali Hostal Guayaquil
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
7.0 out of 10, Good, (41 reviews)
"The hotel was clean. I never figured out the hot water, so took cold shower. Don't know if there wasn't any hot water or I didn't wait long enough for it to be hot. Hotel staff not very friendly. Breakfast was scrambled egg w/ white toast and coffee. Milk for coffee was curdled. We paid $66. The hotel didn't have our reservation, so I was glad to have reservation printed out from internet. The cost of rooms at the desk was slightly higher. It was not worth the $66.00 paid, but it was not...
United States
Anonymous traveller
Murali Hostal Guayaquil

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (617 reviews)
"Very nice place to stay ! "
United States
Diana
The price is NZ$169
1 Feb - 2 Feb
Sheraton Guayaquil Hotel

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 4.6 km from Santa Maria
10.0 out of 10, Exceptional, (9 reviews)
"Wonderful hosts and felt like home "
United States
Tina
The price is NZ$117
1 Feb - 2 Feb
Hostal Macaw

Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (109 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
The price is NZ$660
2 Mar - 3 Mar
Hotel del Parque

Malecon Guesthouse

Malecon Guesthouse
3.0 star property
River City, 7.9 km from Santa Maria
The price is NZ$41
4 Feb - 5 Feb
Malecon Guesthouse

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 5.1 km from Santa Maria
9.0 out of 10, Wonderful, (10 reviews)
"You can walk to the airport."
United States
Digna
Suitesecu Rentals Guayaquil

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent location, service, room and property. "
United States
Angela
The price is NZ$150
1 Feb - 2 Feb
TRYP by Wyndham Guayaquil Airport

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel with great breakfast and dining"
United States
Eulalia
The price is NZ$150
1 Feb - 2 Feb
Oro Verde Guayaquil

Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 7.9 km from Santa Maria
8.0 out of 10, Very good, (389 reviews)
"Great customer service, very kind staff, amazing location"
Canada
Maria Lorena
Hotel Ramada

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 7.9 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is NZ$713
2 Feb - 3 Feb
Hotel Río Guayas by Art Hotels Ecuador

San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 6 km from Santa Maria
6.2 out of 10, (23 reviews)
"Receptionist was very helpful finding us delivery food on arrival."
United States
William
The price is NZ$58
1 Feb - 2 Feb
San Francisco Apart Hotel

Fortune Hotel

Fortune Hotel
3.0 star property
River City, 7.7 km from Santa Maria
8.0 out of 10, Very good, (7 reviews)
"Very bad Hotel. Not using Expedia again. "
United States
Bryan
The price is NZ$83
3 Feb - 4 Feb
Fortune Hotel

PRAGA APARTMENTS

PRAGA APARTMENTS
4.0 star property
Urdesa, 4.2 km from Santa Maria
9.0 out of 10, Wonderful, (15 reviews)
"Great place to stay at "
United States
Eric
PRAGA APARTMENTS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

Bolívar

While Bolívar may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Malecon Mall and Civic Center.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travellers are sure to enjoy a stay in Guayaquil's Santa Maria neighbourhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals in Santa Maria.
What can I see and do in this Guayaquil neighbourhood?
Salón de Eventos Rubi, City Mall and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.