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Santa Maria Hotels, Guayaquil

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Check prices for these dates

This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

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Our top choices for Santa Maria hotels

A modern interior with a seating area, a kitchen, and a dining space.

1. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,005 reviews)
"Loved the closeness to Guayaquil airport, the staff was amazing, will definitely stay there again."
United States
Giovanna
The price is NZ$185
26 Sept - 27 Sept
Holiday Inn Guayaquil Airport by IHG
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

2. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,004 reviews)
"Good staff, excelent food. I will defenetly will come back"
United States
Gloria E
The price is NZ$151
11 Sept - 12 Sept
Courtyard by Marriott Guayaquil
A modern bar area with a bar counter, stools, and a seating area with a table and chairs.

3. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is NZ$151
13 Sept - 14 Sept
Wyndham Garden Guayaquil
A high-rise hotel interior with multiple floors, large windows, and modern lighting fixtures.

4. Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.8 out of 10, Excellent, (976 reviews)
"All the friendly staff at the Hilton colon I recommend"
United States
Jazmin
The price is NZ$201
28 Sept - 29 Sept
Hilton Colon Guayaquil
An outdoor patio with wicker furniture, a stone wall, and a water feature.

5. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 4.7 km from Santa Maria
8.4 out of 10, Very good, (255 reviews)
"👍"
United States
Marcos
The price is NZ$108
3 Sept - 4 Sept
Hotel Marcelius
A buffet setup with pastries and various food items in jars.

6. Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (683 reviews)
"It has been a great experience staying at the Sheraton. The staff is friendly, professional, and welcoming. The rooms are clean, spacious, and comfortable. Overall, it is definitely a great place to stay, and I would highly recommend it to anyone visiting Guayaquil."
United States
James T
The price is NZ$184
12 Sept - 13 Sept
Sheraton Guayaquil Hotel
An outdoor seating area with wicker chairs and a table, a glass wall with a reflection, and hanging orange lights.

7. Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.6 out of 10, Excellent, (282 reviews)
"The staff was very nice and helpful, the room was very clean along with their good smelling towels. Area seemed very safe."
United States
Diana
The price is NZ$108
6 Sept - 7 Sept
Hotel Puerto Pacifico Guayaquil Airport
A pool area with lounge chairs, a waterfall, and tropical plants.

8. Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is NZ$192
6 Sept - 7 Sept
Iguanazu Bed & Breakfast
A reception desk with a marble top and a modern light fixture above it.

9. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,006 reviews)
"Great place to stay near the airport and just steps from Mall del Sol"
United States
Carlos
The price is NZ$161
13 Sept - 14 Sept
TRYP by Wyndham Guayaquil Airport

10. DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (653 reviews)
"Nice, clean simple, family run hotel with good transportation."
United States
Gerald
The price is NZ$63
3 Sept - 4 Sept
DC Suites Aeropuerto
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a seating area with tables and chairs.

11. Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 4.6 km from Santa Maria
8.6 out of 10, Excellent, (92 reviews)
"Staff was very helpful and nice. The property was well kept, and well located"
United States
Jazmin
The price is NZ$134
4 Sept - 5 Sept
Cedros Inn Boutique Hotel
A spacious indoor area with a central open space surrounded by seating arrangements and a pool.

12. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (727 reviews)
"Great property"
United States
Joseph
The price is NZ$170
6 Sept - 7 Sept
Radisson Hotel Guayaquil
An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

13. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"I enjoyed everything about this hotel."
United States
Maria Dorila
The price is NZ$136
2 Oct - 3 Oct
Grand Hotel Guayaquil, Centro Histórico.
A person in a swimsuit and red hat sitting on a green inflatable ring in a pool.

14. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,008 reviews)
"Great breakfast, friendly and helpful staff."
United States
VICENTE
The price is NZ$175
18 Sept - 19 Sept
Oro Verde Guayaquil
A modern bar area with a bar counter, seating, and a large window.

15. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,006 reviews)
"Great hotel to stay in! Staff was super friendly!"
United States
Isabel
The price is NZ$218
13 Sept - 14 Sept
Wyndham Guayaquil Puerto Santa Ana
A person in a white robe sitting on a bed with a tray containing breakfast items like fruit, juice, and cereal.

16. MC Suites

MC Suites
3.5 star property
Kennedy, 4.4 km from Santa Maria
8.2 out of 10, Very good, (141 reviews)
"Staff is great and they are pending that you enjoy time in the hotel!"
United States
Sofia
The price is NZ$84
5 Sept - 6 Sept
MC Suites
A building with a traditional architectural style, featuring a prominent entrance with a set of stairs leading up to a double door.

17. Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is NZ$164
2 Sept - 3 Sept
Luxva Hotel Boutique
A rooftop terrace with outdoor seating, a bar area, and potted plants.

18. Harmonie

Harmonie
2.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (106 reviews)
"Very friendly staff and clean hotel. The bed and the pillows could do with upgrading but everything else was great!"
United Kingdom
Theresa
The price is NZ$73
2 Oct - 3 Oct
Harmonie
An outdoor seating area with tables and chairs, potted plants, and a view of trees through large windows.

19. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 8.1 km from Santa Maria
9.4 out of 10, Exceptional, (335 reviews)
"Great location."
United States
George S
The price is NZ$114
4 Sept - 5 Sept
Ibis Styles El Malecon Guayaquil
A courtyard with a fountain, seating area, and a building with a dome and clock tower.

20. Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (133 reviews)
"Wonderful stay for our family of four!!! A+++++++ experience on all levels!!!"
United States
Brianna Meighan
The price is NZ$798
27 Sept - 28 Sept
Hotel del Parque
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Botanical Garden while you're familiarising yourself with the larger area.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Top Santa Maria Hotel Reviews

Recent Reviews in Santa Maria

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"Honestly recommend staff was very helpful understanding"
Julio 3-night trip
Posted 3 hours ago
Oro Verde Guayaquil

Frequently asked questions

When is the best time to go to Santa Maria?
The best time to visit Santa Maria is during the dry season, which runs from May to December, offering pleasant weather for exploring.

During these months, you'll experience less humidity and more sunshine, making it ideal for enjoying outdoor activities and sightseeing. The temperatures are consistently warm but not overly hot, typically ranging from 25°C to 30°C. This period is great for travellers who prefer clear skies and comfortable conditions for their adventures.

For those interested in wildlife, particularly birdwatching, the dry season is especially rewarding as many species are more active and visible.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Santa Maria hotel for you.
How can I save on a hotel booking in Santa Maria with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Maria hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Maria?
Hotel prices in Santa Maria often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.

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