Santa Maria Holidays

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Our guide on where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Our pick of the best Santa Maria Hotel Deals

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
The price is NZ$174 per night from 28 Feb to 1 Mar
NZ$174
28 Feb - 1 Mar
9.2/10 Wonderful! (1,000 reviews)
Clean walking distance from airport. Great staff, good food

Reviewed on 28 Jan 2026

Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is NZ$187 per night from 17 Feb to 18 Feb
NZ$187
17 Feb - 18 Feb
9.2/10 Wonderful! (1,010 reviews)
The entire hotel looks gorgeous. The room was spotless. The staff was fantastic. I highly recommend.

Reviewed on 15 Jan 2026

Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is NZ$150 per night from 1 Feb to 2 Feb
NZ$150
1 Feb - 2 Feb
9.4/10 Exceptional! (1,000 reviews)
Upgrade was excellent as wss the complimentary airport transfers.

Reviewed on 25 Jan 2026

Oro Verde Guayaquil
See all 424 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria holiday package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1 000 000 hotels worldwide, your Santa Maria holiday package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream holiday in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favourites.
How far in advance should I book my Santa Maria holiday?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your holiday time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia holiday package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria holiday package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Discover the most popular places to visit in Santa Maria

Seaside Malecon 2000 walkway with Santa Ana Hill, Ecuador

Santa Ana Hill

3/5(3 reviews)

Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.

Santa Ana Hill

San Marino Mall

During your visit to Guayaquil, you can do some window-shopping at San Marino Mall. Visit the area's cathedral or simply enjoy its seafood restaurants.

San Marino Mall

Riocentro Los Ceibos

During your visit to San Eduardo, you can search for that perfect souvenir at Riocentro Los Ceibos. Visit the area's cathedral or simply enjoy its seafood restaurants.

Riocentro Los Ceibos

Activities

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

NZ$112
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Making hot Chocolate!

Cocoa farm and Chocolate making!

NZ$269
per adult
Cocoa farm and Chocolate making!
Santa Ana Hill

Guayaquil City Tour Including the Light House of Cerro Santa Ana

NZ$243
per adult
Guayaquil City Tour Including the Light House of Cerro Santa Ana
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.