Midtown Hotels, St. Louis

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28 Dec - 29 Dec
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29 Dec - 30 Dec
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2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

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Our top choices for Midtown hotels

Courtyard
Element St. Louis Midtown

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (651)
"Everything was excellent. The staff were very friendly and helpful. The accommodations were excellent and it was a great location near every where we were going."
United States
Angela
The price is NZ$262
includes taxes & fees
4 Jan - 5 Jan 2026
Element St. Louis Midtown
BBQ/picnic Area
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1003)
"Room was as expected. "
United States
Ruth
The price is NZ$224
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott St Louis Downtown
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.4 out of 10, Very good, (4038)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is NZ$200
includes taxes & fees
30 Dec - 31 Dec
Hyatt Regency St. Louis at The Arch
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3 km from Midtown
8.8 out of 10, Excellent, (1173)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is NZ$198
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2769)
"Great place to stay before your early morning flight. "
United States
Henry
The price is NZ$182
includes taxes & fees
2 Jan - 3 Jan 2026
Pear Tree Inn St. Louis Airport
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3286)
"The room was great , the staff was awesome breakfast and evening drinks and food were great overall it was an excellent stay "
United States
Daniel
The price is NZ$288
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel St. Louis at the Arch
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
9.3 km from Midtown
9.4 out of 10, Exceptional, (842)
"Clean, would stay again."
United States
Eryka
The price is NZ$230
includes taxes & fees
8 Jan - 9 Jan 2026
Courtyard by Marriott St. Louis Brentwood
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.8 km from Midtown
8.8 out of 10, Excellent, (3046)
"Clean room, good breakfast and good location "
United States
Martin
The price is NZ$196
includes taxes & fees
30 Dec - 31 Dec
Clayton Plaza Hotel & Extended Stay
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (650)
"The room was very clean and the staff is always friendly "
United States
Lynn
The price is NZ$179
includes taxes & fees
1 Jan - 2 Jan 2026
Country Hearth Inn & Suites Edwardsville St. Louis
Restaurant
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
26.6 km from Midtown
9.6 out of 10, Exceptional, (1006)
"The staff was top notch. Wonderful area."
United States
Catherine
The price is NZ$211
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites St. Louis O'Fallon, IL
Exterior
Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.2 out of 10, Wonderful, (712)
"Room spotless staff friendly "
United States
Allen
The price is NZ$177
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Troy by IHG
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
8.8 out of 10, Excellent, (1255)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is NZ$224
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton St. Louis Downtown
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1455)
"Everything was absolutely wonderfull"
United States
Suada
The price is NZ$209
includes taxes & fees
13 Jan - 14 Jan 2026
River City Casino & Hotel
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 3.5 km from Midtown
8.8 out of 10, Excellent, (1192)
"The staff was probably the best part of the stay. "
United States
Ja Nelle
The price is NZ$196
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very good, (1059)
"While the water constantly ran in the bathtub, the staff was amazing, the beds were comfy enough, the free breakfast was filling and checkout was easy. "
United States
jessica
The price is NZ$168
includes taxes & fees
4 Jan - 5 Jan 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Free daily continental breakfast
Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very good, (1003)
"I enjoy staying here."
United States
Kelley
The price is NZ$121
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Troy IL/St. Louis Area
Suite, 1 Bedroom, City View | Living room
Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1002)
"Was a great stay. "
United States
Lorilyn
The price is NZ$197
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott St. Louis Downtown/Convention Center
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.8 out of 10, Excellent, (1020)
"Staff were real nice. Accommodating. "
United States
Tim
The price is NZ$217
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Pennywell St. Louis at the Arch
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars)
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
17.2 km from Midtown
9.2 out of 10, Wonderful, (1506)
"Good transport to and from car rental, a plus "
United States
Ralph
The price is NZ$218
includes taxes & fees
1 Jan - 2 Jan 2026
Wingate by Wyndham St. Louis Airport
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West, 2.5 km from Midtown
8.0 out of 10, Very good, (620)
"Great stay "
United States
Kevin
The price is NZ$156
includes taxes & fees
3 Jan - 4 Jan 2026
Home2 Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Top Midtown Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"Great great room. Perfect hotel. Don’t love that the lobby is on the top floor. Really great bar and views. "
Rosalyn 1-night trip
Posted 20 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Residence Inn by Marriott St Louis Downtown is the highest ranked property in Midtown. This hotel is a short 14-minute walk from St. Louis University, and it offers in-room kitchens and a 24-hour fitness centre.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 30 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Busch Stadium are some popular places to visit in the area around Midtown. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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