Top Hotels Near Mayo Clinic Florida in Jacksonville from NZ$215

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (136 reviews)
"Great place to stay"
United States
Judy
The price is NZ$350
includes taxes & fees
19 Feb - 20 Feb
Hilton Jacksonville At Mayo Clinic

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (460 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is NZ$364
includes taxes & fees
12 Feb - 13 Feb
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (571 reviews)
"Very good hotel"
United States
Careli
The price is NZ$215
includes taxes & fees
15 Feb - 16 Feb
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Enjoyed the complimentary breakfast. "
United States
Andrew
The price is NZ$215
includes taxes & fees
15 Feb - 16 Feb
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1,009 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is NZ$215
includes taxes & fees
21 Feb - 22 Feb
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (760 reviews)
"Great location "
United States
Josiah Christine
The price is NZ$304
includes taxes & fees
28 Feb - 1 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Salt Air Inn & Suites

Salt Air Inn & Suites
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (429 reviews)
"The room was roomy and clean very close to the beach and lot's of food options within walking distance "
United States
abilio
Salt Air Inn & Suites

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (535 reviews)
"Great place (and location)!"
United States
Dale
The price is NZ$272
includes taxes & fees
1 Mar - 2 Mar
Element Jacksonville Beach

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,004 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is NZ$255
includes taxes & fees
19 Feb - 20 Feb
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (293 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is NZ$338
includes taxes & fees
12 Feb - 13 Feb
The Hotel Palms

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (75 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is NZ$236
includes taxes & fees
15 Feb - 16 Feb
TownePlace Suites by Marriott® Jacksonville Mayport

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,027 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is NZ$231
includes taxes & fees
15 Feb - 16 Feb
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (176 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is NZ$319
includes taxes & fees
8 Feb - 9 Feb
AC Hotel Jacksonville St Johns Town Center

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,609 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is NZ$253
includes taxes & fees
8 Feb - 9 Feb
Margaritaville Jacksonville Beach

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,001 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is NZ$272
includes taxes & fees
22 Feb - 23 Feb
Hyatt Place Jacksonville / St. Johns Town Center

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (634 reviews)
"The hotel was great! Very clean room and staff were very courteous and professional"
United States
Mike
The price is NZ$351
includes taxes & fees
1 Mar - 2 Mar
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,008 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is NZ$246
includes taxes & fees
9 Feb - 10 Feb
Best Western Oceanfront

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is NZ$301
includes taxes & fees
1 Mar - 2 Mar
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Hotel was clean, breakfast was perfect."
United States
Kurt
The price is NZ$240
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express Jacksonville Beach by IHG

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is NZ$383
includes taxes & fees
1 Mar - 2 Mar
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.6
Exceptional
136 reviews
View
Lobby
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
460 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
571 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,002 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.6
Excellent
1,009 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Hotels near other Mayo Clinic Florida attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 45 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at Players by the Sea, SeaWalk Pavillion and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.