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Hilton Jacksonville At Mayo Clinic

4.5 star property

Choose dates to view prices

A short walk from Mayo Clinic Florida, Hilton Jacksonville At Mayo Clinic provides a corner/local shop, a firepit and dry cleaning/laundry services. The on-site American cuisine restaurant, Coastal Kitchen, offers breakfast, lunch, dinner and children's meals. Stay connected with free in-room WiFi, with a speed of 25+ Mbps, and guests can find other amenities, such as a bar and a gym.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Parking included
  • Free Wi-Fi
  • Restaurant
  • Air-conditioning
  • Gym
The current price is NZ$338
includes taxes & fees
4 Apr - 5 Apr

Room options

Available filters for rooms
Showing 20 of 20 rooms

View all photos for Room, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed

8.0 out of 10
Very good
(3 reviews)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed (Water View)

View from room

Deluxe Room, 1 King Bed (Water View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Sofa bed - single
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

View from room

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Sofa bed - single
  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Corner

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Corner

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Sofa bed - single
  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Zero Count)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Zero Count)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View)

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View, Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)

Room, 1 King Bed, Accessible (Roll-In Shower)

Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds

9.6 out of 10
Exceptional
(21 reviews)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Water View, Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Hearing)

8.0 out of 10
Very good
(1 review)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds (Water View)

10.0 out of 10
Exceptional
(1 review)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub (View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Blackout curtains
Premium bedding
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

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About the area

Jacksonville is home to Hilton Jacksonville At Mayo Clinic. Players by the Sea and Beaches Museum & History Park are cultural highlights, and some of the area's landmarks include Ribault Monument and Fort Caroline National Memorial. Looking to enjoy an event or a game while in town? See what's happening at EverBank Stadium or Jacksonville Beach Tennis Center. Visit our Jacksonville travel guide
Map
4745 Transformation Way, Jacksonville, FL, 32224

What's nearby

  • Jacksonville_MayoClinicFlorida_6127706_04
    Mayo Clinic Florida
    1 min walk - 0.0 km
  • Jacksonville_UniversityofNorthFlorida_6127797_04
    University of North Florida
    6 min drive - 8.3 km
  • Jacksonville_StJohnsTownCenter_6127793_05
    St. Johns Town Center
    8 min drive - 11.6 km
  • While attending the Florida Lighthouse Association's annual conference we visited two lighthouses on the Mayport Base. We beat the rain before heading back to the conference.
    Mayport Naval Station
    17 min drive - 18.6 km
  • F/A-18 Hornets at NAS Jacksonville
    Jacksonville Naval Air Station
    32 min drive - 47.0 km

Getting around

  • Jacksonville Station
    28 min drive
  • Jacksonville International Airport (JAX)
    33 min drive

Restaurants

  • Culver’s
    3 min drive
  • Starbucks
    3 min drive
  • Circle K
    16 min walk
  • M Brothers at Mayo
    14 min walk
  • Starbucks
    13 min walk

About this property

Hilton Jacksonville At Mayo Clinic

Luxury hotel near St. Johns Town Center
A short walk from Mayo Clinic Florida, Hilton Jacksonville At Mayo Clinic provides a corner/local shop, a firepit and dry cleaning/laundry services. The on-site American cuisine restaurant, Coastal Kitchen, offers breakfast, lunch, dinner and children's meals. In addition to a bar and a gym, guests can connect to free in-room WiFi, with a speed of 25+ Mbps.
Other perks at this hotel include:
  • An outdoor pool, along with sunloungers and pool umbrellas
  • Free self-parking
  • Buffet breakfast (surcharge), a free local area shuttle and an electric car charging station
  • Express check-out, concierge services and a TV in reception
Room features
All 252 rooms include comforts such as premium bedding and laptop-compatible safes, as well as perks such as late-night room service and free WiFi.
Extra conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Baths or showers, hairdryers and shampoo
  • 55-inch Smart TVs with Netflix, streaming services and premium channels
  • Mini fridges, free infant beds and coffee/tea makers

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • In-room WiFi speed: 25+ Mbps
  • Available in some public areas: Free WiFi

Parking and transport

  • Electric car charging station on site
  • Free area shuttle up to 350 yards
  • Free uncovered self parking on site
  • Limited on-site self parking

Food and drink

  • Daily buffet breakfast available 6:00 AM to 10:30 AM for a fee: USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • A bar/lounge
  • A restaurant

Restaurants on site

  • Coastal Kitchen
  • Coastal Kitchen Bar

Things to do

  • Gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Free area shuttle
  • Grocery/convenience store
  • In-room cot
  • Laundry facilities
  • Mini-fridge
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop
  • Proposal/romance packages
  • Wedding services

Business services

  • 12 meeting rooms
  • 20,000 square feet of conference space
  • Coworking space

Outdoors

  • Firepit
  • Outdoor furniture
  • Pool loungers
  • Pool umbrellas

Accessibility

  • Tile flooring in public areas

More

  • 1 building
  • 8 floors
  • At least 80% lighting from LEDs
  • At least 80% of food locally-sourced
  • Built in 2025
  • Comprehensive food waste policy
  • Smoke-free property
  • Traditional architecture
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Blackout drapes
  • Free cot
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Free bottled water
  • Late-night room service
  • Mini-fridge

More

  • Air conditioning
  • Free local calls
  • Free long-distance calls
  • Heating
  • Iron/ironing board
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 5:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed

Children and extra beds

Children are welcome
2 children, per adult, up to the age of 18 years, can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are available for USD 50.00 per night.
Free cots are available on request at the property

Payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Breakage deposit: USD 100 per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for buffet breakfast: approximately USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • Rollaway bed fee: USD 50.00 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher and a smoke detector

We should mention

Pool access available from 8:00 AM to 10:00 PM
Only registered guests are allowed in the guestrooms
A car is not required for transport to and from this property
Guests under 16 years old are not allowed in the fitness facility, and guests under 16 years old are only allowed in the swimming pool with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Hilton Jacksonville At Mayo Clinic Hotel
Hilton Jacksonville At Mayo Clinic Jacksonville
Hilton Jacksonville At Mayo Clinic Hotel Jacksonville

Frequently asked questions

Does Hilton Jacksonville At Mayo Clinic have a pool?

Yes, this property has an outdoor pool. Pool access is from 8:00 AM to 10:00 PM.

How much does it cost to stay at Hilton Jacksonville At Mayo Clinic?

As of 9 Mar 2026, prices found for a 1-night stay for 2 adults at Hilton Jacksonville At Mayo Clinic on 4 Apr 2026 start from NZ$338, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hilton Jacksonville At Mayo Clinic pet-friendly?

No, pets are not allowed at this property.

How much is parking at Hilton Jacksonville At Mayo Clinic?

Self-parking is free at this property.

What time is check-in at Hilton Jacksonville At Mayo Clinic?

Check-in start time: 4:00 PM; check-in end time: 5:00 AM. Late check-in is available during limited hours.

What time is check-out at Hilton Jacksonville At Mayo Clinic?

Checkout is at 11:00 AM.

Where is Hilton Jacksonville At Mayo Clinic located?

Situated in Jacksonville, this luxury hotel is 0.3 mi (0.5 km) from Mayo Clinic Florida and 2.8 mi (4.4 km) from Harbor City Municipal Golf Course. Windsor Commons Shopping Center and Windsor Parke Golf Club are also within 6 miles (10 km).

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Reviews

Hilton Jacksonville At Mayo Clinic Reviews

9.4

Exceptional

9.8

Cleanliness

9.4

Amenities

9.6

Staff & service

9.8

Property conditions & facilities
Rating 10 - Excellent. 138 out of 171 reviews
Rating 8 - Good. 15 out of 171 reviews
Rating 6 - Okay. 7 out of 171 reviews
Rating 4 - Poor. 6 out of 171 reviews
Rating 2 - Terrible. 5 out of 171 reviews

Reviews

10/10 Excellent

Schylea

Liked: Cleanliness, amenities, property conditions & facilities
Clean rooms, friendly staff close to Mayo Clinic.
Stayed 2 nights in Jan 2026

10/10 Excellent

Julie

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful, clean, great atmosphere, very nice staff!
Stayed 2 nights in Dec 2025

10/10 Excellent

Gary

Yes very clean beautiful and nice staff. Conveniently located to Mayo.
Stayed 2 nights in Dec 2025

10/10 Excellent

Mohsin

Liked: Cleanliness, amenities, property conditions & facilities
Newly constructed, very clean and well maintained. Great staff. Highly recommend.
Stayed 1 night in Jan 2026

10/10 Excellent

Christian

Liked: Cleanliness, property conditions & facilities
The hotel looks like brand new! Modern and clean.
Stayed 1 night in Jan 2026

10/10 Excellent

Albert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff and rooms
Stayed 1 night in Oct 2025

10/10 Excellent

Erron

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very nice hotel. Food is excellent and friendly staff.
Stayed 2 nights in Oct 2025

10/10 Excellent

Joahnna

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, comfortable, nice restaurant & coffee shop.
Stayed 3 nights in Oct 2025

10/10 Excellent

michael

Liked: Cleanliness, amenities, property conditions & facilities
Room was great and spacious. hoteal and bar staff was very accomodating
Stayed 1 night in Dec 2025

10/10 Excellent

Carrie

Liked: Cleanliness, amenities, property conditions & facilities
Room was amazing. Staff friendly and very knowledgeable!
Stayed 1 night in Dec 2025

10/10 Excellent

Cathy

Liked: Cleanliness, staff & service, amenities
Room was spotless, new hotel, wonderful friendly staff
Stayed 1 night in Oct 2025

10/10 Excellent

Christy

Liked: Cleanliness, amenities, property conditions & facilities
Staff courteous. Room great
Stayed 1 night in Dec 2025

10/10 Excellent

Steven

Liked: Cleanliness, amenities, property conditions & facilities
Room with spotless. Staff was courteous. The amenities excellent.
Stayed 1 night in Dec 2025

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, property conditions & facilities
Clean. Very friendly staff.
Stayed 1 night in Nov 2025

10/10 Excellent

Shearn

Liked: Cleanliness, staff & service, property conditions & facilities
Very nice facility and staff. Would recommend to anyone visiting the Mayo Clinic.
Stayed 2 nights in Nov 2025

10/10 Excellent

Jermaine

Liked: Cleanliness, amenities, property conditions & facilities
Overall my stay was wonderful. Any concerns that I needed was addressed ASAP. Staff was friendly and helpful. I will stay here again.
Stayed 1 night in Nov 2025

10/10 Excellent

Shahriar

Liked: Cleanliness, amenities, property conditions & facilities
This is by far the best Hilton in the country. Super modern, clean and classy. The room was also super nice, clean and spacious.
Stayed 1 night in Nov 2025

10/10 Excellent

Doria

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful and clean..quiet . I stayed on 8th floor
Stayed 1 night in Dec 2025

10/10 Excellent

Pratul

Liked: Cleanliness, amenities, property conditions & facilities
Room was spotless. Friendly staff
Stayed 2 nights in Nov 2025

10/10 Excellent

Varun

Liked: Cleanliness, amenities
Lot of efforts taken to make guests feel special and comfortable. Special thoughts were given to address many minor details. Breakfast had lot of variety and the pool was open till 10 PM. It was perfect for staying during family vacation.
Stayed 3 nights in Nov 2025

10/10 Excellent

Mousmee

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It is a newly built hotel, so rooms wete in good condition. Staff was very friendly and respectful. Id you do not have car, it will be chellenging to go aroubd.
Stayed 3 nights in Nov 2025

10/10 Excellent

NaJai

Liked: Cleanliness, staff & service, amenities
Everything was so perfect ! The staff was amazing! Everything was spotless . 10/10 I recommend! I will definitely be back ! 😇
Stayed 2 nights in Nov 2025

10/10 Excellent

Laurie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This property is brand new and it was so nice. The staff was very helpful and very nice. We went there for Mayo Clinic. The shuttle was nice so we didn’t have to drive to the hospital and area doctor visits and tests. Wish there was a shuttle from the airport. Overall a very nice hotel.
Stayed 1 night in Oct 2025

10/10 Excellent

sherry

Liked: Cleanliness, amenities, property conditions & facilities
Friendly staff and lovely hotel it was nice and quiet with easy parking. I enjoyed the stay. I would recommend that they have a more organized lost and found system, I left a bunch of items and instead of just bundling all leftover items together for pick up I had to call in multiple times whenever I found another thing missing to ask them to look for it. They could have just put it all in one and sort by room to make it more efficient.
Stayed 3 nights in Dec 2025

6/10 Okay

John

Liked: Cleanliness, amenities, property conditions & facilities
Very clean nice rooms! Beds are terrible. It’s like someone slept on one side of the bedroom for 20 years without turning the bed….it goes uphill from one side to the other! Very nice room though with great facilities!
Stayed 1 night in Dec 2025