A free breakfast buffet, a poolside bar and a free food/drink shopping service are just a few of the amenities provided at Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Stay connected with free in-room WiFi, and guests can find other amenities, such as a garden and dry cleaning/laundry services.
Isle of Palms, a neighbourhood in Jacksonville, is home to Residence Inn By Marriott Jacksonville - Mayo Clinic Area. San Jose Episcopal Church and Fort Caroline National Memorial are local landmarks, and some of the area's activities can be experienced at TPC Sawgrass and Windsor Parke Golf Club. Ready for a night out? Consider Lynch's Irish Pub and The Spot Hookah Lounge. Visit our Jacksonville travel guide
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
What's nearby
University of North Florida
5 min drive - 9.0 km
St. Johns Town Center
8 min drive - 12.6 km
TPC Sawgrass
15 min drive - 14.6 km
Mayport Naval Station
21 min drive - 18.6 km
EverBank Stadium
21 min drive - 30.2 km
Getting around
Jacksonville, FL (CRG-Jacksonville Executive at Craig)
17 min drive
Restaurants
Culver’s
4 min drive
Circle K
9 min walk
Starbucks
4 min drive
Al's Pizza
5 min drive
Southern Grounds
3 min drive
About this property
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Hotel near St. Johns Town Center
A free breakfast buffet, a poolside bar and a free food/drink shopping service are just a few of the amenities provided at Residence Inn By Marriott Jacksonville - Mayo Clinic Area. In addition to a garden and dry cleaning/laundry services, guests can connect to free in-room WiFi.
Additional perks include:
An outdoor pool, along with sunloungers
Free self-parking
Express check-out, smoke-free property and luggage storage
A water dispenser, a 24-hour front desk and a computer station
Guest reviews say great things about the helpful staff
Room features
All 155 rooms boast comforts, such as laptop-compatible safes and laptop-friendly workspaces, in addition to perks, such as air conditioning and separate sitting areas. Guest reviews speak positively of the cleanliness rooms at the property.
Other conveniences in all rooms include:
Bathrooms with baths or showers and free toiletries
55-inch Smart TVs with Netflix, streaming services and premium channels
Separate sitting areas, separate dining areas and recycling
Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a pool?
Yes, this property has an outdoor pool.
How much does it cost to stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
As of 25 Oct 2026, prices found for a 1-night stay for 2 adults at Residence Inn By Marriott Jacksonville - Mayo Clinic Area on 13 Nov 2026 start from NZ$293, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Residence Inn By Marriott Jacksonville - Mayo Clinic Area pet-friendly?
Yes, this property allows cats and dogs (limit 2 total) with a maximum weight of up to 18 kg per pet. There's a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much is parking at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Self-parking is free at this property.
What time is check-in at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Check-in start time: 4:00 PM; check-in end time: 6:00 AM. Late check-in is available during limited hours.
What time is check-out at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?
Checkout is at 11:00 AM.
Where is Residence Inn By Marriott Jacksonville - Mayo Clinic Area located?
Located in Isle of Palms, this hotel is within 1 mi (2 km) of Atlantic Intracoastal Waterway and Mayo Clinic Florida. Windsor Commons Shopping Center and Windsor Parke Golf Club are also within 6 miles (10 km).
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Great hotel with clean, comfortable rooms and friendly staff. The location was convenient, and the breakfast was delicious. Overall, we had a pleasant stay and would definitely recommend it.
We stayed in one bedroom unit. The whole unit was super clean, the arrangement was super comfortable. Beds were super soft and I adore white sheets and blankets! The atmosphere was quite. Breakfast was aboundant and nutritious, lots of options.
The suite room we had was nice with a full kitchen, dining and living area that was separate from the sleeping area. I will definitely recommend this room to anyone needing to stay near the Mayo Clinic.
Breakfast was ok nothing special but the staff were all helpful and upbeat. Would highly recommend this property especially if you’re going to Mayo Clinic.
Great place for long term stay, you get a great breakfast buffet every day, rooms are nice with kitchen, good beds, living room and tvs. The kitchen has a 2 unit stove, microwave, dish washer, sink, refrigerator and a few kitchen plates pots and utensils. the only down side is the shower because the glass is too small and water poors on the floor. I mitigated that by installing a shower courtain with an extended pole. Parking is free and is a 2 minute drive to Mayo clinic. They also offer a shuttle to take you to Mayo Clinic.