La Guillotière Hotels, Lyon

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for La Guillotière hotels

Front of property – evening/night
Ibis Lyon Centre

Ibis Lyon Centre

Ibis Lyon Centre
3.0 star property
La Guillotière
7.8 out of 10, Good, (176)
"nice place to stay "
France
lahouari
The price is NZ$164
includes taxes & fees
18 Jan - 19 Jan 2026
Ibis Lyon Centre
Property amenity
Hotel de Noailles

Hotel de Noailles

Hotel de Noailles
3.0 star property
La Guillotière
7.4 out of 10, Good, (118)
"Beautiful property right next to dining and shopping. Highly recommended!"
United States
John
Hotel de Noailles
Terrace/patio
Ho36 hostels

Ho36 hostels

Ho36 hostels
La Guillotière
8.0 out of 10, Very good, (162)
"Great value hostel, safe comfortable and convenient "
United Kingdom
David
The price is NZ$157
includes taxes & fees
11 Jan - 12 Jan 2026
Ho36 hostels
Exterior
Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu
3.0 star property
1.5 km from La Guillotière
9.0 out of 10, Wonderful, (1230)
"Great stay and correct price very good restaurant "
Spain
Antonio
The price is NZ$168
includes taxes & fees
30 Jan - 31 Jan 2026
Campanile PRIME - Lyon Centre Gare Part Dieu
Premium Double Room
Globe et Cecil Hôtel

Globe et Cecil Hôtel

Globe et Cecil Hôtel
4.0 star property
Bellecour - Hôtel Dieu, 1.6 km from La Guillotière
8.4 out of 10, Very good, (532)
"Very nice stay, loved the location and the hotel! "
Sweden
Sandra
The price is NZ$259
includes taxes & fees
10 Jan - 11 Jan 2026
Globe et Cecil Hôtel
Classic Double Room
Republik Hôtel

Republik Hôtel

Republik Hôtel
3.0 star property
Bellecour - Hôtel Dieu, 1.5 km from La Guillotière
8.6 out of 10, Excellent, (339)
"Everything was great!"
Canada
Polina
The price is NZ$206
includes taxes & fees
4 Jan - 5 Jan 2026
Republik Hôtel
Junior Suite
Hotel Vaubecour

Hotel Vaubecour

Hotel Vaubecour
2.0 star property
2nd Arrondissement, 1.9 km from La Guillotière
9.2 out of 10, Wonderful, (327)
"This hotel is located in a great area with easy access to the train station, metro stations, and lots of shopping and restaurants. The staff is very nice and helpful. Would definitely stay here again!"
Canada
Nicholas
The price is NZ$171
includes taxes & fees
25 Jan - 26 Jan 2026
Hotel Vaubecour
Restaurant
Bikube Lyon

Bikube Lyon

Bikube Lyon
4.0 star property
3rd Arrondissement, 1.1 km from La Guillotière
9.0 out of 10, Wonderful, (201)
"Everything was great! Staff were alway friendly and helpful! Room was immaculate. Shared living space was cool. Close to Metro. Highly recommend!"
United States
Kathleen
The price is NZ$161
includes taxes & fees
3 Jan - 4 Jan 2026
Bikube Lyon
Classic Room with balcony including self-service snacks and drinks at the Club
OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre
4.0 star property
1.7 km from La Guillotière
9.0 out of 10, Wonderful, (1003)
"freindly staff, clean room, nice location."
United States
Cami
The price is NZ$223
includes taxes & fees
9 Jan - 10 Jan 2026
OKKO Hotels Lyon Centre
Daily buffet breakfast (EUR 10 per person)
Premiere Classe Lyon Centre - Gare Part Dieu

Premiere Classe Lyon Centre - Gare Part Dieu

Premiere Classe Lyon Centre - Gare Part Dieu
2.0 star property
Part Dieu - Bir Hakeim, 1 km from La Guillotière
8.0 out of 10, Very good, (1001)
"Very comfy bed, opening window "
Australia
Sarah
The price is NZ$101
includes taxes & fees
5 Jan - 6 Jan 2026
Premiere Classe Lyon Centre - Gare Part Dieu
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon
4.0 star property
Fourvière, 2.8 km from La Guillotière
9.2 out of 10, Wonderful, (1003)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Restaurant
Hôtel des Célestins

Hôtel des Célestins

Hôtel des Célestins
3.0 star property
Bellecour - Hôtel Dieu, 1.7 km from La Guillotière
9.2 out of 10, Wonderful, (397)
"This is the perfect location and a beautiful smaller hotel, highly recommend."
United States
Steven
The price is NZ$205
includes taxes & fees
3 Jan - 4 Jan 2026
Hôtel des Célestins
Classic Room, 1 Double Bed (Pure)
Greet Hotel Lyon Confluence

Greet Hotel Lyon Confluence

Greet Hotel Lyon Confluence
3.0 star property
Perrache, 1.7 km from La Guillotière
8.8 out of 10, Excellent, (184)
"The room was very clean. Staff were great. Breakfast buffet was very good"
Canada
Patti
The price is NZ$163
includes taxes & fees
30 Jan - 31 Jan 2026
Greet Hotel Lyon Confluence
City view from property
Novotel Lyon Gerland Musée des Confluences

Novotel Lyon Gerland Musée des Confluences

Novotel Lyon Gerland Musée des Confluences
4.0 star property
2.8 km from La Guillotière
8.2 out of 10, Very good, (1001)
"The hotel is ok, staff friendy and good options inside the hotel. However, it is not so close to the old town, it takes more than 15 minutes by car. Our room fridge was not working, we informed the reception, yet it was never fixed. The rooms are ok, but not sound proof. We heard everything from the corridor, and it was pretty noisy."
Ireland
Maria
The price is NZ$155
includes taxes & fees
16 Jan - 17 Jan 2026
Novotel Lyon Gerland Musée des Confluences
Front of property
Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

Hotel Silky by HappyCulture
4.0 star property
Les Cordeliers, 1.9 km from La Guillotière
8.8 out of 10, Excellent, (975)
"Amazing location and hotel. Perfect for seeing the sites and coming back and feeling welcomed by the staff. Great breakfast too!"
Canada
Cameron
The price is NZ$194
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Silky by HappyCulture
Lobby sitting area
The Ruck Hotel

The Ruck Hotel

The Ruck Hotel
4.0 star property
Gerland, 3.1 km from La Guillotière
9.0 out of 10, Wonderful, (209)
"Wasn’t a very good breakfast choice , staff were very helpful and efficient "
United Kingdom
yasmin
The Ruck Hotel
Front of property
ibis Styles Lyon Centre - Gare Part Dieu Hotel

ibis Styles Lyon Centre - Gare Part Dieu Hotel

ibis Styles Lyon Centre - Gare Part Dieu Hotel
3.0 star property
1.4 km from La Guillotière
8.8 out of 10, Excellent, (1001)
"Breakfast was great. The shower head was fantastic."
United States
Ian
The price is NZ$208
includes taxes & fees
16 Jan - 17 Jan 2026
ibis Styles Lyon Centre - Gare Part Dieu Hotel
Exterior
Le Phenix Hotel

Le Phenix Hotel

Le Phenix Hotel
4.0 star property
Old Lyon, 2.5 km from La Guillotière
9.2 out of 10, Wonderful, (1000)
"Fantastic location with excellent rooms"
United States
Hudson
The price is NZ$235
includes taxes & fees
4 Jan - 5 Jan 2026
Le Phenix Hotel
Exterior
ibis Lyon Centre Perrache

ibis Lyon Centre Perrache

ibis Lyon Centre Perrache
3.0 star property
Perrache, 1.7 km from La Guillotière
8.8 out of 10, Excellent, (935)
"Clean with comfortable bed and good shower. In walking distance of places to visit. Near station."
United Kingdom
alan
The price is NZ$161
includes taxes & fees
18 Jan - 19 Jan 2026
ibis Lyon Centre Perrache
Bar (on property)
Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette
4.0 star property
3rd Arrondissement, 1.3 km from La Guillotière
8.8 out of 10, Excellent, (1002)
"Nice workout facility with dipping pool. "
Canada
Sue
The price is NZ$218
includes taxes & fees
3 Jan - 4 Jan 2026
Mercure Lyon Centre Saxe Lafayette
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in La Guillotière

Find the best La Guillotière areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Place Carnot – discover Lyon City Centre, a destination also famous for its shopping.

Lyon featuring a city, a river or creek and a statue or sculpture

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Cinema and Miniature Museum. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour Square showing a river or creek, a statue or sculpture and a bridge

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

2nd Arrondissement

Travellers love 2nd Arrondissement for its popular shops, and you can see more of Lyon by jumping on the metro at Place des Archives or Sainte-Blandine Tram Stop. You might spend time checking out top sights like Place Carnot and Lyon Confluence Shopping Center.

Top La Guillotière Hotel Reviews

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

10/10 Excellent
"beautiful place, quiet rooms"
Julien 3-night trip
Posted 5 days ago
Fourvière Hôtel Lyon

Frequently asked questions

What is La Guillotière like?
La Guillotière is a neighbourhood that travellers like for its riverfront, shopping and restaurants.
Where is the best hotel for a stay in La Guillotière?
Based on Expedia customer reviews, Hotel de Noailles is a highly ranked property in La Guillotière. This hotel is a short 11-minute walk from Bellecour Square, and it offers free WiFi and parking. Another top choice in the area is Ho36 hostels.
How many hotels should I expect to find in the La Guillotière area?
If you're searching for places to stay in Lyon, Expedia has something to meet your needs with 41 La Guillotière hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in La Guillotière, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review top deals in La Guillotière.
What is there to do around this Lyon neighbourhood?
Carrousel du Pont de la Guillotière, Museum of the Resistance and Centre d'Histoire de la Resistance et de la Deportation are just a few of the places to visit in and around La Guillotière. La Part-Dieu Business District and Tour Part-Dieu are also worth a visit when you're out sightseeing in Lyon.
How can I get around La Guillotière and the greater Lyon area?
For a quick way to explore the city, catch a ride on metro transit at Garibaldi Station, Saxe-Gambetta Station or Saint-André Tram Stop.

Explore a world of travel with Expedia