South Main Travel Guide
Tourist Guide
Visit South Main
Popular places to visit
NRG Stadium
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the great live music and lively festivals in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and great live music in this vibrant area.
Space Center Houston
The Johnson Space Centre played a key role in twentieth century history and has become synonymous with the dream of space exploration.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed art galleries and entertainment choices in this vibrant area.
Activities
Space Center Houston Admission Ticket
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston: Houston Botanic Garden Entry Ticket
From Houston: Crocodile Encounter Entry Ticket
Our pick of the best South Main Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
Staff was pleasant and helpful. Room was clean comfortable and spacious
Reviewed on 31 Jan 2026
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Room was very clean and spacious! They promptly brought us linens for the couch bed and extra towels when we called!
Reviewed on 26 Jan 2026
Club Quarters Hotel Downtown, Houston
Very helpful, however they need more heat in the lobby for their workers and need to fix the second elevator because it took to long to get to your room
Reviewed on 27 Jan 2026
The Royal Sonesta Houston Galleria
My welcome was the best part: I was told, “welcome home! You’re going to be with us for a while!” It was so genuine and sweet. My room was comfortable, quiet and the location was ideal.
Reviewed on 26 Jan 2026
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
The room was nice but
Reviewed on 25 Jan 2026
The Whitehall Houston
Great hotel and staff.
Reviewed on 24 Jan 2026
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Astrodome, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
