Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the lively festivals and great live music in this vibrant area.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed theatre scene and great live music in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theatre scene and entertainment choices in this vibrant area.
Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's fascinating museums and acclaimed art galleries.
University of Houston
Walk around the campus of University of Houston, a top university in Houston. Experience the fascinating museums and acclaimed theatre scene in this vibrant area.
Activities
Houston Museum of Natural Sciences: Planetarium Ticket
Houston: Houston Botanic Garden Entry Ticket
Houston City Tour and Downtown Aquarium All Rides Pass
Our pick of the best South Main Hotel Deals
Wyndham Houston near NRG Park/Medical Center
Reviewed on 16 Jul. 2025
The Whitehall Houston
Reviewed on 18 Jul. 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Reviewed on 19 Jul. 2025
Club Quarters Hotel Downtown, Houston
Reviewed on 18 Jul. 2025
Hilton Americas-Houston
Reviewed on 14 Jul. 2025
Cambria Hotel Houston Downtown Convention Center
Reviewed on 17 Jul. 2025
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Houston Museum District. Top attractions like Houston Zoo and Children's Museum of Houston are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Children's Museum of Houston and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.