A tree-lined landscape with a river and fields.

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Check prices for these dates

Tonight
11 Sept - 12 Sept
Tomorrow
12 Sept - 13 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"Clean room. The front desk was very kind and helpful."
Mercedes 3-night trip
Posted 2 hours ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent
"A"
Barbara 1-night trip
Posted 12 hours ago
Fairfield Inn & Suites by Marriott Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"All good, staff friendly and helpful! Breakfast was great and kick back dinner was good!"
Randy 1-night trip
Posted 19 hours ago
Drury Inn & Suites Sikeston, MO
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"We had no problem checking in. The room was nice and clean. The staff were courteous and helpful. Parking was acceptable. Close to our room. No complaints."
Carol 2-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area
Quality Inn Union City US 51

Quality Inn Union City US 51

8/10 Good
"The staff was fantastic! Super friendly and helpful. The bed was so comfortable!! It made me realize how badly I need a new mattress!!"
kara 1-night trip
Posted 3 days ago
Quality Inn Union City US 51
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Really quiet place close to good restaurants and stores."
james 1-night trip
Posted 3 days ago
Hampton Inn Sikeston
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

10/10 Excellent
"This was a great location. The staff were friendly, the facility clean, and all the amenities were up to date and working properly. The gym is open 24 hours!"
Randal 2-night trip
Posted 4 days ago
Holiday Inn Express & Suites Union City by IHG
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 4 days ago
The Riverstone Hotel Charleston-Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

8/10 Good
"Great location, nice, clean and well maintained, Hotel employees were very helpful great customer service,"
Bernice 2-night trip
Posted 4 days ago
Best Western Plus Sikeston I-55

More cheap accommodation in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
NZ$111
20 Sept - 21 Sept
includes taxes & fees
7/10 Good! (673 reviews)
Super 8 by Wyndham Sikeston/Miner Area
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO
NZ$123
16 Sept - 17 Sept
includes taxes & fees
8.4/10 Very good! (821 reviews)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
NZ$129
13 Sept - 14 Sept
includes taxes & fees
Days Inn and Suites by Wyndham Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

1111 BLue Heron Lane Union City TN
NZ$147
11 Oct - 12 Oct
includes taxes & fees
Sleep Inn at Discovery Park of America
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
NZ$170
20 Sept - 21 Sept
includes taxes & fees
8.4/10 Very good! (1,009 reviews)
Best Western Plus Sikeston I-55
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
NZ$198
11 Oct - 12 Oct
includes taxes & fees
9/10 Wonderful! (621 reviews)
Hampton Inn Sikeston

Frequently asked questions

What is the best area to stay in East Prairie?
The best area to stay in East Prairie is near Main Street, particularly around the intersection with Washington Street.This central part of East Prairie offers the most convenience for visitors. It's where you'll find the majority of local businesses, including eateries and shops. The area is quite walkable, allowing you to easily explore the town's core.For travellers looking for a straightforward and practical base, staying near Main Street is ideal.
When is the best time to go to East Prairie?
The best time to visit East Prairie, Missouri, is typically during the spring (April to May) and autumn (September to October) months.These seasons offer the most pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the town and its surrounding natural areas. Spring brings blooming flowers and lush greenery, while autumn showcases beautiful fall foliage, particularly along the nearby Mississippi River.For those interested in local festivities, visiting in September allows you to experience the annual Sweet Corn Festival, a significant event for the town.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in East Prairie.
How can I save on a hotel booking in East Prairie with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on East Prairie hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in East Prairie?
Prices for hotels in East Prairie often vary, but you can find a great deal from NZ$99 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

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