East Prairie Hotel & Accommodation Deals 2026 from NZ$94 - Fully Refundable Options

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for East Prairie hotels

A building with a fountain and flower beds in front.

1. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

2. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

includes taxes & fees

18 Nov - 19 Nov

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

3. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

4. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

zandra

includes taxes & fees

29 Oct - 30 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

5. Hampton Inn Sikeston

Sikeston

Deborah

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

6. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

includes taxes & fees

1 Nov - 2 Nov

A conference room with a long table, multiple chairs, and a television screen on the wall.

7. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

8. Best Western Plus Sikeston I-55

Sikeston

Shelley

includes taxes & fees

8 Nov - 9 Nov

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

9. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Roslyn

includes taxes & fees

8 Nov - 9 Nov

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

10. Country Yard Inn and Suite

Sikeston

Marianne

includes taxes & fees

29 Oct - 30 Oct

11. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

includes taxes & fees

8 Nov - 9 Nov

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

12. Comfort Inn & Suites Sikeston I-55

Sikeston

Fred

includes taxes & fees

18 Nov - 19 Nov

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

13. Eagle Inn Charleston

Charleston

Jackson

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

14. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Laura

includes taxes & fees

5 Nov - 6 Nov

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

15. Super 8 By Wyndham Marston

Marston

Wendy

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a glass table and checkered chairs, an exit door, and a vending machine.

16. Travel Inn Marston I-55 by Hotel O

Marston

Frank

includes taxes & fees

29 Oct - 30 Oct

A reception area with a reception desk, two blue armchairs, a round table, and a glass door leading outside.

17. Sleep Inn at Discovery Park of America

Union City

Ben

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a reception desk, seating area, and a large window.

18. Quality Inn Cairo I-57

Cairo

Santiago

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a reception desk, seating areas, and a large abstract art piece on the wall.

19. Holiday Inn Express & Suites Union City by IHG

Union City

Kevin

includes taxes & fees

26 Nov - 27 Nov

A hotel dining area with a long counter, multiple tables, and chairs. There are curtains on the windows, a lamp, and a view of the outdoors.

20. Quality Inn Union City US 51

Union City

Logan

includes taxes & fees

17 Nov - 18 Nov

View all properties

Compare top hotels in East Prairie

The Riverstone Hotel Charleston-Sikeston 2.5 star property Charleston View	Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 2.5 star property Sikeston View	Drury Inn & Suites Sikeston, MO 3.0 star property Sikeston View	Super 8 by Wyndham Charleston/Sikeston East MO 2.0 star property Charleston View	Hampton Inn Sikeston 2.5 star property Sikeston View
6.8 443 reviews	8.4 Very good 829 reviews	9.6 Exceptional 1,004 reviews	6.8 681 reviews	9.0 Wonderful 649 reviews
The price is NZ$131 includes taxes & fees 29 Oct - 30 Oct	The price is NZ$125 includes taxes & fees 18 Nov - 19 Nov	The price is NZ$190 includes taxes & fees 1 Nov - 2 Nov	The price is NZ$117 includes taxes & fees 29 Oct - 30 Oct	The price is NZ$191 includes taxes & fees 22 Nov - 23 Nov
Yes, Breakfast included Yes, Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie

A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

Super 8 by Wyndham Charleston/Sikeston East MO

8/10 Good

"Ice machine was not working, it just out of ice. Everything else was good."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"We had a nice overnight stay here. The sleeper/sofa was not comfortable, but very few are. It was a good selection of foods for the breakfast. We especially enjoyed the coffee machine that freshly grinds the coffee beans and brews it immediately. We also liked the style of the luggage carts. They were less bulky and easier to handle."

The Dragonfly - Sleeps up to 8, Lake views.

10/10 Excellent

"This was the perfect place for us to stay when we were in town for the real foot art and craft show the house was clean. Nice size. We loved the views we had. A a fire that we sat around with and did some mores. It was just wonderful Kristi the host was awesome, very responsive and helpful. Hope to stay there again in the future!"

More cheap accommodation in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

NZ$116

5 Nov - 6 Nov

includes taxes & fees

Frequently asked questions

What is the best area to stay in East Prairie?

The best area to stay in East Prairie is near Main Street, particularly around the intersection with Washington Street.

This central part of East Prairie offers the most convenience for visitors. It's where you'll find the majority of local businesses, including eateries and shops. The area is quite walkable, allowing you to easily explore the town's core.

For travellers looking for a straightforward and practical base, staying near Main Street is ideal.

When is the best time to go to East Prairie?

The best time to visit East Prairie, Missouri, is typically during the spring (April to May) and autumn (September to October) months.

These seasons offer the most pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the town and its surrounding natural areas. Spring brings blooming flowers and lush greenery, while autumn showcases beautiful fall foliage, particularly along the nearby Mississippi River.

For those interested in local festivities, visiting in September allows you to experience the annual Sweet Corn Festival, a significant event for the town.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to 'My Trips' and selecting your reservation. To find flexible deals, filter your search by 'Fully refundable property' for hotels in East Prairie.

How can I save on a hotel booking in East Prairie with Expedia?

One Key™—Expedia's free travel rewards programme—gives you instant access to discounts with Member Prices on East Prairie hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

How much is the nightly rate for a hotel in East Prairie?

Prices for hotels in East Prairie often vary, but you can find a great deal from NZ$94 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by 'Price: low to high' for our cheapest rates.

Explore a world of travel with Expedia

Book Hotels in East Prairie on Expedia.com

Search East Prairie hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in East Prairie

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for East Prairie hotels

1. The Riverstone Hotel Charleston-Sikeston

2. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

3. Drury Inn & Suites Sikeston, MO

4. Super 8 by Wyndham Charleston/Sikeston East MO

5. Hampton Inn Sikeston

6. Days Inn and Suites by Wyndham Sikeston

7. Holiday Inn Express & Suites Sikeston Southwest by IHG

8. Best Western Plus Sikeston I-55

9. Fairfield Inn & Suites by Marriott Sikeston

10. Country Yard Inn and Suite

11. TownePlace Suites by Marriott Sikeston

12. Comfort Inn & Suites Sikeston I-55

13. Eagle Inn Charleston

14. Super 8 by Wyndham Sikeston/Miner Area

15. Super 8 By Wyndham Marston

16. Travel Inn Marston I-55 by Hotel O

17. Sleep Inn at Discovery Park of America

18. Quality Inn Cairo I-57

19. Holiday Inn Express & Suites Union City by IHG

20. Quality Inn Union City US 51

Compare top hotels in East Prairie

The Riverstone Hotel Charleston-Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Drury Inn & Suites Sikeston, MO

Super 8 by Wyndham Charleston/Sikeston East MO

Hampton Inn Sikeston

Stay near popular East Prairie attractions

Big Oak Tree State Park

Learn more about East Prairie

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

Super 8 by Wyndham Charleston/Sikeston East MO

More cheap accommodation in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app