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Check prices for these dates

Tonight
7 Feb - 8 Feb
Tomorrow
8 Feb - 9 Feb
Next weekend
13 Feb - 15 Feb
In two weeks
20 Feb - 22 Feb

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Our top choices for East Prairie hotels

Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,002 reviews)
"As always it was a perfect visit"
United States
John
The price is NZ$172
includes taxes & fees
12 Feb - 13 Feb
Drury Inn & Suites Sikeston, MO
Lobby

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (552 reviews)
"Very clean nice staff and well run "
United States
zach
The price is NZ$142
includes taxes & fees
9 Feb - 10 Feb
Country Hearth Inn & Suites Union City
Room, 1 Queen Bed, Non Smoking

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (45 reviews)
"Great hotel, great staff"
United States
Dmitry
The price is NZ$123
includes taxes & fees
9 Feb - 10 Feb
Super 8 By Wyndham Marston
Lobby

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (341 reviews)
"The rooms are big and the property is spotless!"
United States
debbie
The price is NZ$149
includes taxes & fees
1 Mar - 2 Mar
Sleep Inn at Discovery Park of America
Free daily continental breakfast

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
"Stay was excellent "
United States
Kourtney
The price is NZ$188
includes taxes & fees
13 Feb - 14 Feb
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (477 reviews)
"Great place for an overnight stay. I will be back!"
United States
Jenny
The price is NZ$184
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn Sikeston
Individually decorated, individually furnished, desk, blackout curtains

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (735 reviews)
"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."
United States
Becky
The price is NZ$111
includes taxes & fees
9 Feb - 10 Feb
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (56 reviews)
"Clean rooms great staff"
United States
IRA
The price is NZ$190
includes taxes & fees
19 Feb - 20 Feb
Fairfield Inn & Suites by Marriott Sikeston
Front of property

The Riverstone Hotel

The Riverstone Hotel
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is NZ$129
includes taxes & fees
9 Feb - 10 Feb
The Riverstone Hotel
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (739 reviews)
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (622 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is NZ$115
includes taxes & fees
9 Feb - 10 Feb
Super 8 by Wyndham Charleston/Sikeston East MO
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,004 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is NZ$161
includes taxes & fees
22 Feb - 23 Feb
Best Western Plus Sikeston I-55
Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (276 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is NZ$129
includes taxes & fees
2 Mar - 3 Mar
Quality Inn Cairo I-57
Iron/ironing board, free WiFi, bed sheets

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.6 out of 10, (122 reviews)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is NZ$102
includes taxes & fees
9 Feb - 10 Feb
Country Yard Inn and Suite
Exterior

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (313 reviews)
"The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction."
United States
Angela
The price is NZ$217
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Express & Suites Union City by IHG
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,001 reviews)
"Everything was excellent"
United States
James
The price is NZ$129
includes taxes & fees
10 Feb - 11 Feb
Days Inn and Suites by Wyndham Sikeston
Free buffet breakfast

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (493 reviews)
"Nice room"
Mexico
José Ricardo
The price is NZ$133
includes taxes & fees
22 Feb - 23 Feb
Quality Inn Union City US 51
Terrace/patio

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (170 reviews)
"Spotless , friendly staff."
United States
Gail
The price is NZ$219
includes taxes & fees
14 Feb - 15 Feb
Hampton Inn Union City
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
"Middle of nowhere hotel was ok"
United States
David
The price is NZ$118
includes taxes & fees
11 Feb - 12 Feb
Eagle Inn Charleston
Desk, free WiFi, bed sheets, alarm clocks

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (286 reviews)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is NZ$164
includes taxes & fees
22 Feb - 23 Feb
Comfort Inn & Suites Sikeston I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

3.8/5 (8 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Clean comfy stay ! Thanks"
James 1-night trip
Posted 6 days ago
Days Inn and Suites by Wyndham Sikeston

More cheap accommodation in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO
The price is NZ$111 per night from 9 Feb to 10 Feb
NZ$111
9 Feb - 10 Feb
includes taxes & fees
8.4/10 Very Good! (733 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best holiday rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: This holiday home rental outside of East Prairie is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 33 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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