The Mississippi River near Hannibal, Missouri, USA

East Prairie Holiday Rentals

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Our top choices for East Prairie holiday rentals

Tranquil charming Tiny House in Clinton

Tranquil charming Tiny House in Clinton
Clinton
10.0 out of 10, Exceptional, (2 reviews)
"It is clean and comfortable. Would definitely stay again if ever in the area."
United States
Jennifer M.
The price is NZ$262
includes taxes & fees
28 June - 29 June
Tranquil charming Tiny House in Clinton

Tiny house on the lake with tv free internet walk shower

Tiny house on the lake with tv free internet walk shower
Tiptonville
10.0 out of 10, Exceptional, (1 review)
"Dave was very accommodating and the home was clean."
United States
Katherine P.
The price is NZ$403
includes taxes & fees
26 June - 27 June
Tiny house on the lake with tv free internet walk shower

Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak
9.6 out of 10, Exceptional, (33 reviews)
"Location was great. We were down for a few days fishing."
United States
Andrew
The price is NZ$421
includes taxes & fees
28 June - 29 June
Come and relax at the Refuge at beautiful Reelfoot Lake!

Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (5 reviews)
"Nice place. "
United States
Andrew E.
The price is NZ$284
includes taxes & fees
2 July - 3 July
Vacation rental attached to our house out in the country.

Charming 3-bedroom house with free wifi and coffee it is close to the lake

Charming 3-bedroom house with free wifi and coffee it is close to the lake
Hornbeak
10.0 out of 10, Exceptional, (10 reviews)
"If David isn't labeled as a super host, he definitely should be!!! We loved our stay & will returning often!!"
United States
Carla H.
The price is NZ$461
includes taxes & fees
25 June - 26 June
Charming 3-bedroom house with free wifi and coffee it is close to the lake

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
Hornbeak
9.8 out of 10, Exceptional, (57 reviews)
"Great place to stay! Clean and convenient location what more can you ask for! "
United States
Austin E.
The price is NZ$424
includes taxes & fees
25 June - 26 June
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

3-bedroom house in charming Tiptonville with cool AC and washer and dryer

3-bedroom house in charming Tiptonville with cool AC and washer and dryer
Tiptonville
10.0 out of 10, Exceptional, (1 review)
"Easy to get along with and great communication. "
United States
Shane W.
The price is NZ$414
includes taxes & fees
25 June - 26 June
3-bedroom house in charming Tiptonville with cool AC and washer and dryer

Sunkist beach house. Lake side house 3 bedroom house

Sunkist beach house. Lake side house 3 bedroom house
Tiptonville
10.0 out of 10, Exceptional, (5 reviews)
"Great experience!! A quality stay with great communication from Host. Will be back! "
United States
Steven L.
The price is NZ$533
includes taxes & fees
7 July - 8 July
Sunkist beach house. Lake side house 3 bedroom house

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak
10.0 out of 10, Exceptional, (10 reviews)
"As long time visitors to Reelfoot this is hands down the best place we have ever stayed! We rented for a family hunting trip and the property is amazing. "
United States
Paul M.
The price is NZ$622
includes taxes & fees
5 July - 6 July
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

The Hut II on Reelfoot Lake

The Hut II on Reelfoot Lake
Hornbeak
9.6 out of 10, Exceptional, (10 reviews)
"It’s one of our favorite places to stay. "
United States
Laura W.
The price is NZ$450
includes taxes & fees
7 July - 8 July
The Hut II on Reelfoot Lake

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Hornbeak
9.8 out of 10, Exceptional, (61 reviews)
The price is NZ$452
includes taxes & fees
6 July - 7 July
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is NZ$639
includes taxes & fees
29 June - 30 June
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Union City
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful place to relax. Home has everything you need. The additional party barn is an added bonus!!"
United States
william P.
The price is NZ$670
includes taxes & fees
30 June - 1 July
Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Prairie Hotel Reviews

Find out more about East Prairie

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our East Prairie holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up East Prairie. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in East Prairie. Seeing all the best attractions is bound to make you fall in love with East Prairie. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in East Prairie short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a holiday rental in East Prairie?

Yes, there are holiday rentals close to the most popular sights in East Prairie, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that East Prairie has to offer?

The Tackle Box at Reelfoot: This holiday home rental outside of East Prairie has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave.

What can I see and do in East Prairie?

Big Oak Tree State Park and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the wider area, you’ll find Central Park and Sikeston Depot Museum.

What are holiday rentals like in East Prairie?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in East Prairie. Holiday rentals offer amenities like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitised environment, holiday rentals can provide a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for family trips or small group gatherings.