The Mississippi River near Hannibal, Missouri, USA

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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place!"
United States
Jennifer
The price is NZ$223
includes taxes & fees
6 July - 7 July
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (580 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is NZ$221
includes taxes & fees
2 July - 3 July
Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (470 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is NZ$214
includes taxes & fees
12 July - 13 July
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (93 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is NZ$220
includes taxes & fees
2 July - 3 July
Fairfield Inn & Suites by Marriott Sikeston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (400 reviews)
"The room was clean, the breakfast was good. We enjoyed our stay."
United States
David
The price is NZ$183
includes taxes & fees
22 July - 23 July
Sleep Inn at Discovery Park of America

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (418 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
United States
Soheila
The price is NZ$146
includes taxes & fees
28 June - 29 June
The Riverstone Hotel Charleston-Sikeston

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (571 reviews)
"Ok place to say the night if you are looking for a place to sleep. "
United States
Paul
The price is NZ$109
includes taxes & fees
7 July - 8 July
Country Hearth Inn & Suites Union City

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,003 reviews)
"Very convenient and staff was great."
United States
jeanne
The price is NZ$167
includes taxes & fees
19 July - 20 July
Best Western Plus Sikeston I-55

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (776 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is NZ$92
includes taxes & fees
28 June - 29 June
New Orleans Inn Portageville

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very good, (65 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
United States
Amy
The price is NZ$166
includes taxes & fees
29 June - 30 June
Super 8 By Wyndham Marston

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.2 out of 10, Very good, (526 reviews)
"Breakfast was filling and fresh. Short overnight stay which completely met our needs First level room with convenient vehicle parking right outside the door which made moving luggage painless. "
United States
Lisa
The price is NZ$138
includes taxes & fees
30 June - 1 July
Quality Inn Union City US 51

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (186 reviews)
"Friendly staff, comfortable bed."
United States
James
The price is NZ$249
includes taxes & fees
28 June - 29 June
Hampton Inn Union City

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (330 reviews)
"I enjoy myself and I will recommend anybody to stay.."
United States
Faye
The price is NZ$226
includes taxes & fees
11 July - 12 July
Holiday Inn Express & Suites Union City by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (792 reviews)
"I love it there."
United States
Sharika West
The price is NZ$132
includes taxes & fees
6 July - 7 July
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again"
United States
Joseph
The price is NZ$252
includes taxes & fees
9 July - 10 July
TownePlace Suites by Marriott Sikeston

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (499 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is NZ$140
includes taxes & fees
28 June - 29 June
Reelfoot Lake Inn

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (641 reviews)
"Clean rooms,"
United States
Karl
The price is NZ$116
includes taxes & fees
19 July - 20 July
Super 8 by Wyndham Charleston/Sikeston East MO

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (139 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
United States
Sheryl
The price is NZ$113
includes taxes & fees
10 July - 11 July
Country Yard Inn and Suite

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (393 reviews)
"Traveling through the area. It met our needs."
United States
Pamela
The price is NZ$125
includes taxes & fees
28 June - 29 June
Hospitality House Union City I 69 / US 51

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,000 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is NZ$137
includes taxes & fees
14 July - 15 July
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

The Mississippi River near Hannibal, Missouri, USA

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