Downtown South San Francisco Hotels, San Francisco

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4599 Cheap Hotels in Downtown South San Francisco - Specials, Reviews, & Last Minute Deals

Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very good, (2035)
"Great place to stay "
The price is NZ$229
includes taxes & fees
2 Oct - 3 Oct
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (958)
"The inside is super nice and clean. Very pleasant"
The price is NZ$188
includes taxes & fees
28 Sept - 29 Sept
Airport Inn

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
Inn By The SFO

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is NZ$254
includes taxes & fees
24 Sept - 25 Sept
Miller Apartments

Galleria Park Hotel

4.0 star property
9.6 out of 10, Exceptional, (1017)
"Great boutique style hotel. Staff was excellent!"
The price is NZ$385
includes taxes & fees
5 Oct - 6 Oct
Galleria Park Hotel

citizenM San Francisco Union Square

4.0 star property
9.6 out of 10, Exceptional, (1382)
"Great stay"
The price is NZ$349
includes taxes & fees
17 Oct - 18 Oct
citizenM San Francisco Union Square

Chancellor Hotel on Union Square

3.5 star property
9.4 out of 10, Exceptional, (2949)
"Great hotel!"
The price is NZ$203
includes taxes & fees
30 Sept - 1 Oct
Chancellor Hotel on Union Square

citizenM Menlo Park

4.0 star property
9.4 out of 10, Exceptional, (150)
"nice place to stay in the area"
The price is NZ$263
includes taxes & fees
27 Sept - 28 Sept
citizenM Menlo Park

Hotel Emblem San Francisco

4.0 star property
9.4 out of 10, Exceptional, (1006)
"It was simply perfect, very close to everything and a variety of dining options that are always a plus."
The price is NZ$371
includes taxes & fees
17 Oct - 18 Oct
Hotel Emblem San Francisco

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2576)
"Everything from the staff to the location was excellent. Will definitely stay here again."
The price is NZ$503
includes taxes & fees
17 Oct - 18 Oct
Hotel Nikko San Francisco

The Clift Royal Sonesta San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1308)
"Amazing room and great location"
The price is NZ$427
includes taxes & fees
5 Oct - 6 Oct
The Clift Royal Sonesta San Francisco

Hotel Zoe Fisherman's Wharf

4.0 star property
9.2 out of 10, Wonderful, (1492)
"Great place to stay "
The price is NZ$700
includes taxes & fees
12 Oct - 13 Oct
Hotel Zoe Fisherman's Wharf

Beacon Grand, A Union Square Hotel

4.0 star property
9.2 out of 10, Wonderful, (1767)
"Very nice hotel. "
The price is NZ$448
includes taxes & fees
19 Oct - 20 Oct
Beacon Grand, A Union Square Hotel

Hyatt Regency San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1906)
"Hotel was beautiful! "
The price is NZ$457
includes taxes & fees
25 Sept - 26 Sept
Hyatt Regency San Francisco

Inn At Union Square

3.5 star property
9.2 out of 10, Wonderful, (1020)
"Such a quaint hotel loved the atmosphere "
The price is NZ$312
includes taxes & fees
25 Sept - 26 Sept
Inn At Union Square

White Swan Inn

3.5 star property
9.2 out of 10, Wonderful, (1004)
"Great room and breakfast "
The price is NZ$350
includes taxes & fees
25 Sept - 26 Sept
White Swan Inn

Hotel Majestic

3.5 star property
9.2 out of 10, Wonderful, (1024)
"Nice, nostalgic hotel. Would definitely stay there again. "
The price is NZ$277
includes taxes & fees
1 Oct - 2 Oct
Hotel Majestic

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6876)
"It was very close to tourist points, breakfast was superb!"
The price is NZ$354
includes taxes & fees
21 Oct - 22 Oct
Hotel Riu Plaza Fisherman's Wharf

Stanford Court San Francisco

4.0 star property
9.0 out of 10, Wonderful, (1328)
"Love this Hotel!"
The price is NZ$366
includes taxes & fees
22 Oct - 23 Oct
Stanford Court San Francisco

Hotel Zelos San Francisco

4.0 star property
9.0 out of 10, Wonderful, (1030)
"Great place! "
The price is NZ$379
includes taxes & fees
5 Oct - 6 Oct
Hotel Zelos San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Fashion puts its best foot forward in one of America’s largest shopping plazas.

Fisherman's Wharf

Taste some of the city’s freshest sea food and catch some fabulous views in this waterfront neighbourhood dating back to the time of the gold rush.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.

What's a favourite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.

How many hotels should I expect to find in the Downtown South San Francisco area?

When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.

What can I see and do in this South San Francisco neighbourhood?

See's Candies, Cinemark Century at Tanforan and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.