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Downtown South San Francisco Hotels, San Francisco

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Our top choices for Downtown South San Francisco hotels

1. La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very good, (2,137 reviews)
"Satisfying stay!"
United States
Andree
The price is NZ$232
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn & Suites by Wyndham San Francisco Airport N

2. Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"One of the best places I’ve stayed in SF area"
United States
Saikiran
The price is NZ$243
includes taxes & fees
15 Nov - 16 Nov
Airport Inn

3. Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.2 out of 10, Good, (26 reviews)
"Nice place to stay"
United States
Tora
The price is NZ$230
includes taxes & fees
27 Nov - 28 Nov
Miller Apartments

4. Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.6 out of 10, Good, (1,001 reviews)
"Awesome place staff was very helpful and friendly room was clean and well organized 10 out of 10"
United States
desmon
Inn By The SFO

5. Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side, 1.1 km from Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"The only negative thing I have to say is that we had to pay parking per night we stayed 😔 Everything else was perfect! Staff was super friendly and place was awesome to stay."
United States
Mary
The price is NZ$219
includes taxes & fees
5 Dec - 6 Dec
Comfort Inn and Suites San Francisco Airport North

6. Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side, 1.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,853 reviews)
"Great breakfast people were very friendly."
Canada
Florence
The price is NZ$311
includes taxes & fees
4 Dec - 5 Dec
Embassy Suites by Hilton San Francisco Airport Oyster Point

7. Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side, 1.5 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,292 reviews)
"Very nice hotel"
United States
John
The price is NZ$259
includes taxes & fees
13 Dec - 14 Dec
Home2 Suites by Hilton San Francisco Airport North

8. Hotel Nova SFO

Hotel Nova SFO
2.5 star property
1.9 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,004 reviews)
"Nice breakfast, clean rooms"
United States
Noel
The price is NZ$207
includes taxes & fees
4 Dec - 5 Dec
Hotel Nova SFO

9. Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side, 1.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,003 reviews)
"The staff was very helpful and friendly"
Canada
Emily
The price is NZ$190
includes taxes & fees
25 Nov - 26 Nov
Hilton Garden Inn San Francisco Arpt North

10. Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
1.8 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,907 reviews)
"We enjoyed the hospitality of staff and the breakfast was great & always stocked !"
United States
Mechelle
The price is NZ$230
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Grosvenor Airport Hotel

11. Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side, 1.3 km from Downtown South San Francisco
7.6 out of 10, Good, (1,684 reviews)
"Everything was super easy from check in to breakfast to airport bus."
United States
Laurel
The price is NZ$168
includes taxes & fees
6 Dec - 7 Dec
Hotel Focus SFO

12. Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point, 2.2 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2,402 reviews)
"Hotel staff was very friendly and the rooms were clean."
United States
Alyssa
The price is NZ$213
includes taxes & fees
23 Nov - 24 Nov
Sonesta Select San Francisco Airport Oyster Point Waterfront

13. The Atrium Hotel at SFO

The Atrium Hotel at SFO
2.5 star property
3 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,037 reviews)
"It was a very nice property, would stay again!"
United States
Jeremy
The price is NZ$220
includes taxes & fees
22 Nov - 23 Nov
The Atrium Hotel at SFO

14. Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
3.7 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,997 reviews)
"Great stay for great price"
United States
Adrian
The price is NZ$210
includes taxes & fees
20 Nov - 21 Nov
Hotel Aluxor SFO

15. DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront
4.0 star property
3.1 km from Downtown South San Francisco
8.2 out of 10, Very good, (1,814 reviews)
"Convenient location"
United States
Alejandro
The price is NZ$191
includes taxes & fees
25 Nov - 26 Nov
DoubleTree by Hilton San Francisco Airport North Bayfront

16. Hotel Skye SFO

Hotel Skye SFO
3.0 star property
3.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,123 reviews)
"We enjoyed our stay"
United States
Yelizaveta
The price is NZ$220
includes taxes & fees
25 Nov - 26 Nov
Hotel Skye SFO

17. The Millwood - A Boutique Hotel

The Millwood - A Boutique Hotel
3.0 star property
5.4 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,047 reviews)
"best stay"
United States
Chitla
The price is NZ$279
includes taxes & fees
11 Dec - 12 Dec
The Millwood - A Boutique Hotel

18. Hotel 1550 - SFO Airport

Hotel 1550 - SFO Airport
3.5 star property
5.1 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,024 reviews)
"clean room helpful staff and airport shuttle was great"
United States
HomerH
The price is NZ$217
includes taxes & fees
21 Nov - 22 Nov
Hotel 1550 - SFO Airport

19. Hotel Aura SFO

Hotel Aura SFO
3.0 star property
4.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,637 reviews)
"Comfortable rooms, nice breakfast, helpful staff."
United States
Pam
The price is NZ$207
includes taxes & fees
3 Dec - 4 Dec
Hotel Aura SFO

20. Aloft by Marriott San Francisco Airport

Aloft by Marriott San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,279 reviews)
"Great hotel overall."
United States
dezzirae
The price is NZ$209
includes taxes & fees
25 Nov - 26 Nov
Aloft by Marriott San Francisco Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Downtown South San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An indoor courtyard with a stone floor, a round table with chairs, and potted plants.
Airport Inn
2.0 star property
9.0
Wonderful
1,000 reviews
View
A La Quinta hotel with a modern facade, a covered entrance, and a parking lot.
La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
8.2
Very good
2,137 reviews
View
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker on the countertop.
Miller Apartments
2.0 star property
7.2
Good
26 reviews
View
A hotel room with two beds, a desk, a chair, a television, and a refrigerator.
Inn By The SFO
2.0 star property
7.6
Good
1,001 reviews
View
A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.
LUMA Hotel San Francisco
4.0 star property
9.6
Exceptional
2,673 reviews
View

Our guide on where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Fashion puts its best foot forward in one of America’s largest shopping plazas.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Taste some of the city’s freshest sea food and catch some fabulous views in this waterfront neighbourhood dating back to the time of the gold rush.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Recent Reviews in Downtown South San Francisco

Frequently asked questions

What other neighbourhoods are similar to Downtown South San Francisco?
While Downtown South San Francisco has its own distinct character, the most similar neighbourhoods in the Bay Area are Burlingame and San Mateo.

Burlingame, located just south of Downtown South San Francisco, offers a comparable experience with its vibrant high street, Burlingame Avenue. This area is known for its upmarket boutiques, diverse restaurants, and independent coffee shops. It's a very walkable neighbourhood, making it convenient for those who enjoy strolling and discovering local businesses.

San Mateo, further south from Burlingame, also shares many characteristics with Downtown South San Francisco. Its downtown area, particularly around 3rd and 4th Avenues, features a variety of dining options, from casual eateries to fine dining establishments, as well as a selection of shops. It's a slightly larger city centre but maintains a similar approachable feel.

Both Burlingame and San Mateo are excellent choices for business travellers or those seeking a convenient base with good transport links to San Francisco and Silicon Valley, much like Downtown South San Francisco.
What are the best hotels in Downtown South San Francisco that travellers recommend?
Two of the best hotels in Downtown South San Francisco that receive consistently high recommendations from travellers are the Airport Inn and the La Quinta Inn & Suites by Wyndham San Francisco Airport N.

The Airport Inn, with an 8.8 rating, is praised for its clean and spacious rooms and comfortable beds. Guests also frequently mention the great location and the friendly staff. It offers convenient amenities like free covered self-parking and a terrace.

Another highly recommended option is the La Quinta Inn & Suites by Wyndham San Francisco Airport N, which has an 8.0 rating. Guests often highlight the comfortable and clean rooms, the great complimentary breakfast, and the friendly and helpful staff. This hotel also provides a free scheduled airport shuttle and 24-hour fitness facilities, making it very convenient for travellers. It is located near points of interest such as the SFO Museum and The Shops at Tanforan.
What are the best family hotels in Downtown South San Francisco?
For family-friendly accommodation in Downtown South San Francisco, you might consider the La Quinta Inn & Suites by Wyndham San Francisco Airport N or the Inn By The SFO.

The La Quinta Inn & Suites by Wyndham San Francisco Airport N, with a rating of 8.0, is a great choice for families. Guests often mention the comfortable and clean rooms, along with the great breakfast, which is complimentary. The hotel also offers a free continental breakfast, a pool, and both cots and sofa beds are available for families. It is conveniently located near the SFO Museum and The Shops at Tanforan, both within 1.8 km.

Another good option is the Inn By The SFO, which has a rating of 7.8. This hotel is praised for its quiet neighbourhood and clean rooms. It provides cots and rollaway extra beds, suiting families. Guests also appreciate the free parking and excellent customer service.
What hotels in Downtown South San Francisco offer free breakfast?
For hotels in Downtown South San Francisco that offer complimentary breakfast, consider the La Quinta Inn & Suites by Wyndham San Francisco Airport N.

The La Quinta Inn & Suites by Wyndham San Francisco Airport N, with a solid 8.0 rating, provides a free continental breakfast to start your day. Guests frequently mention the comfortable and clean rooms, as well as the friendly and helpful staff. This hotel also offers free WiFi and complimentary airport transportation. It is conveniently located near the SFO Museum, which is just 1.8 kilometres away.
What are the top pet-friendly hotels in Downtown South San Francisco?
For a highly-rated pet-friendly hotel in Downtown South San Francisco, consider the La Quinta Inn & Suites by Wyndham San Francisco Airport N.

This hotel boasts an 8.0 rating and is popular for its comfortable and clean rooms, as well as its friendly and helpful staff. Guests frequently praise the great breakfast and convenient location. The hotel permits both dogs and cats, making it an excellent choice for travellers with pets. It is also conveniently located near attractions such as the SFO Museum and The Shops at Tanforan.
What are the best budget hotels in Downtown South San Francisco?
For highly-rated budget hotels in Downtown South San Francisco, consider the La Quinta Inn & Suites by Wyndham San Francisco Airport N, the Inn By The SFO, and Airport Inn.

The La Quinta Inn & Suites by Wyndham San Francisco Airport N, with an 8.0 rating, offers guests comfortable and clean rooms along with a great complimentary breakfast. Its convenient location is often praised, and it provides free WiFi, free toiletries, and free airport transportation. It is also just 1.8 km from the SFO Museum.

Another excellent option is the Inn By The SFO, rated 7.8. Guests appreciate the comfortable beds, clean rooms, and the quiet neighbourhood. It offers free WiFi, free toiletries, and free self-parking. San Bruno Point Park is just 1.8 km away.

Airport Inn, with an 8.8 rating, is top for its clean and spacious rooms, friendly staff, and great location. This hotel provides free WiFi, free toiletries, and free self-parking, including accessible and covered options. It is also close to San Bruno Point Park, which is 1.7 km away.
What are the best hotels in Downtown South San Francisco near San Francisco Bay?
For a hotel in Downtown South San Francisco near San Francisco Bay, consider the Inn By The SFO.

The Inn By The SFO, with a 7.8 rating, is a good option for families travelling with children. Guests appreciate the availability of rollaway extra beds and cribs. The hotel also offers early check-in for an additional charge, which can be useful after a long journey. Guests have frequently commented on the free parking, comfortable beds, and clean rooms. San Bruno Point Park is a short 1.8 km away, and San Francisco Bay is 11.1 km from the hotel. The hotel is situated in a quiet neighbourhood.
When is the best time to go to Downtown South San Francisco?
Downtown South San Francisco is a year-round destination, but the best time to visit is during the late spring and early autumn months, specifically from May to June and September to October.

These periods offer the most pleasant weather conditions, with less fog and generally warmer temperatures compared to the summer. You'll find it comfortable for exploring the local shops and eateries along Grand Avenue or enjoying a stroll in one of the city's parks.

For travellers looking to avoid the busiest tourist seasons and potentially find better value on accommodation, visiting in May or October is ideal. The crowds are typically thinner, and the weather remains agreeable for outdoor activities and day trips to nearby San Francisco or the wine country.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Downtown South San Francisco hotel for you.
How can I save on a hotel booking in Downtown South San Francisco with Expedia?
One Key™—Expedia's free travel rewards programme—gives you instant access to discounts with Member Prices on Downtown South San Francisco hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Downtown South San Francisco?
Hotel prices in Downtown South San Francisco often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.

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