Photo by Jen - Nealys On Wheels

Book Alexander County Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Alexander County hotels

Dining
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is NZ$241
includes taxes & fees
29 Dec - 30 Dec
Cozy cabins on beautiful Horseshoe Lake
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (274)
"Break fast was excellent "
United States
Uma
The price is NZ$135
includes taxes & fees
17 Jan - 18 Jan 2026
Quality Inn Cairo I-57
Exterior
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (20)
"cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation. "
United States
Jason M.
The price is NZ$365
includes taxes & fees
27 Jan - 28 Jan 2026
Peaceful secluded cabin located near Horseshoe Lake
Interior
The Rested Duck Mallard Room

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is NZ$241
includes taxes & fees
1 Jan - 2 Jan 2026
The Rested Duck Mallard Room
Property grounds
Ducks and geese are here! Booking for turkey season too. We're ready for you!

Ducks and geese are here! Booking for turkey season too. We're ready for you!

Ducks and geese are here! Booking for turkey season too. We're ready for you!
2.0 star property
Tamms
10.0 out of 10, Exceptional, (23)
"Great place to stay, nice people"
United States
Jack W.
Ducks and geese are here! Booking for turkey season too. We're ready for you!
Interior
Beautiful Cabin Retreat

Beautiful Cabin Retreat

Beautiful Cabin Retreat
tamms
8.2 out of 10, Very good, (41)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
United States
Randy V.
The price is NZ$405
includes taxes & fees
29 Dec - 30 Dec
Beautiful Cabin Retreat
Outdoor spa tub
NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest

NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest

NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest
Jonesboro
10.0 out of 10, Exceptional, (44)
"Such a fun stay! The lodge is adorable and it’s the perfect little getaway!!"
United States
Summar B.
NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest
Interior
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (4)
"great place. wonderful host."
United States
Carla m.
The price is NZ$431
includes taxes & fees
3 Jan - 4 Jan 2026
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Outdoor spa tub
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (269)
"Had an amazing stay!"
United States
Shauna W.
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Private kitchen
Fabulous cabin with AC in charming Tamms

Fabulous cabin with AC in charming Tamms

Fabulous cabin with AC in charming Tamms
Tamms
Fabulous cabin with AC in charming Tamms
Property grounds
Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks
Jonesboro
10.0 out of 10, Exceptional, (3)
"Very friendly hosts. Met them and they were a pleasure to interact with. They had one of the most complete array of amenities that we have ever encountered in our trips! We did have some issues with losing TV service on our last night, but I imagine that it was not their fault.All in all a pleasant experience."
United States
Timothy S.
Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks
Fridge, microwave, oven, stovetop
Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks
2.0 star property
Jonesboro
10.0 out of 10, Exceptional, (1)
"Property is super cute. Check in was easy. Host communicated very quickly. Had everything you would need to stay for an extended period of time. Delicious zucchini bread provided for breakfast. Easy to find. Would definitely stay here again if we are ever back in Southern Illinois."
United States
Mandy H.
Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks
Front of property – evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (614)
"Staff was great! Room was nice. "
United States
Lana
The price is NZ$118
includes taxes & fees
29 Dec - 30 Dec
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston
2.5 star property
Charleston
6.8 out of 10, (407)
"The staff was very friendly and accommodating "
United States
Arturo
Quality Inn Charleston - Sikeston
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is NZ$115
includes taxes & fees
29 Dec - 30 Dec
Eagle Inn Charleston
Fridge, microwave, oven, stovetop
Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood
Bardwell
10.0 out of 10, Exceptional, (12)
"Quaint stay to see Grand and kids. "
United States
Sheila C.
The price is NZ$275
includes taxes & fees
3 Jan - 4 Jan 2026
Charming 3-bedroom house near ball park in quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Alexander County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Always a pleasant stay. Friendly staff, clean rooms, accessible pool and great food."
Chad 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

Explore a world of travel with Expedia