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Top hotels and accommodation in Cairo

Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is NZ$130
includes taxes & fees
8 Sept - 9 Sept
Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (582)
"Rooms was clean "
The price is NZ$110
includes taxes & fees
8 Sept - 9 Sept
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (397)
"I consistently choose to stay there due to positive past encounters."
The price is NZ$126
includes taxes & fees
8 Sept - 9 Sept
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is NZ$120
includes taxes & fees
1 Sept - 2 Sept
Eagle Inn Charleston
La Center Motel
Basic Double Room

La Center Motel

2.0 star property
7.8 out of 10, Good, (14)
"Front desk staff was amazing. Room was comfy and quiet! Clean! Husband and I needed a place to crash on our long ride home and this motel did not disappoint!"
La Center Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

See all hotels in Cairo

Top Cairo Hotel Reviews

Quality Inn Cairo I-57

Quality Inn Cairo I-57

10/10 Excellent
"The checkin was fast and easy. The room is big and comfortable."
Karen 1-night trip
Posted 11 days ago
Quality Inn Cairo I-57

Frequently asked questions

Where is the best place for a stay in Cairo?

Based on our traveller data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Two other choices for your stay in the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.

What are some of the best holiday rentals that Cairo has to offer?

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!: This holiday home rental outside of Cairo is located in a rural location, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Cairo.

If I need to cancel my hotel reservation in Cairo, will I receive a refund?

Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.

What are some hotels with pools in Cairo?

Quality Inn Cairo I-57 is a top hotel with a seasonal outdoor pool, free full breakfast and free WiFi.

What is staying in Cairo like?

Visitors can enjoy all that Cairo has to offer, including the restaurants, entertainment choices and riverfront. This city also attracts tourists with its small-town vibe. There are 24 hotels and other accommodation options in the surrounding area. Find out more about Cairo.

What should I do while I'm visiting Cairo?

A couple of favourite places to visit are Mississippi River and Fort Defiance State Park. You'll also find Mound City National Cemetery and Columbus-Belmont State Park in the area. Take a look at what more there is to see and do in Expedia's Cairo guide.

What's the seasonal weather like in Cairo?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.