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Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
"The web site said smoking rooms, this is untrue. I was fine with that, but my room smelled like a smoking room. There where cobwebs on the lamps and the tables where dirty. The shower was dirty and had a whole in the ceiling. The outside was very dirty. I would never stay at this hotel aging. I would tell everyone to stay far away from it as they can."
United States
Cyndy
The price is NZ$131
includes taxes & fees
25 July - 26 July
Quality Inn Cairo I-57

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (646 reviews)
"Clean rooms,"
United States
Karl
The price is NZ$116
includes taxes & fees
12 July - 13 July
Super 8 by Wyndham Charleston/Sikeston East MO

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (418 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
United States
Soheila
The price is NZ$146
includes taxes & fees
6 July - 7 July
The Riverstone Hotel Charleston-Sikeston

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
The price is NZ$111
includes taxes & fees
6 July - 7 July
La Center Motel

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is NZ$509
includes taxes & fees
2 Aug - 3 Aug
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

A steel bridge with a sunset in the background.

Top Cairo Hotel Reviews

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More cheap accommodation in Cairo

Find out more about Cairo

Top reasons to visit Cairo

  • Outdoor Adventures: Cairo, Illinois, offers a wealth of outdoor activities, including hiking, camping, and riverboat tours, perfect for nature enthusiasts.
  • Scenic Beauty: Enjoy picturesque landscapes and stunning views that make Cairo an inviting escape for relaxation and exploration.
  • Rich History: Explore the charming streets and historic sites, immersing yourself in the local culture and heritage.
  • Family-Friendly Activities: Engage in various recreational activities suitable for the whole family at local campgrounds.
  • Diverse Accommodations: Choose from a range of welcoming lodgings, including pet-friendly and LGBTQIA-friendly options.

Find great hotels in and around Cairo

Discover a range of welcoming accommodations in Cairo, Illinois, perfect for every traveller. From charming agritourism properties to convenient motels, you'll find pet-friendly options and family-oriented services. Whether you're seeking an LGBTQIA-friendly stay or simply a comfortable place to rest, Cairo's hotels and inns cater to diverse needs, ensuring a memorable visit to this unique destination.

  • Super 8 by Wyndham Charleston/Sikeston East MO: Located a mere 16.1km from Cairo, the Super 8 by Wyndham Charleston/Sikeston East MO offers a budget-friendly motel experience that caters to families and pet owners alike. This establishment prides itself on being family-oriented, providing essential amenities such as free cribs and specific arrangements for younger guests. Additionally, it welcomes pets, ensuring your furry companions can join in on your travels. With a focus on comfort and convenience, this motel is an excellent choice for those seeking a relaxed stay without breaking the bank.
  • The Riverstone Hotel Charleston-Sikeston: Situated 19.3km from Cairo, The Riverstone Hotel Charleston-Sikeston combines budget-friendly pricing with a professional atmosphere ideal for business travellers. This hotel embraces a pet-friendly policy, making it accommodating for those travelling with pets, while also providing a suitable environment for work-related stays. Guests can enjoy essential amenities tailored for comfort and productivity, making it a solid choice for both leisure and business visits in the region.
  • Quality Inn Cairo I-57: Nestled in the heart of Cairo, the Quality Inn Cairo I-57 is a budget-friendly hotel that welcomes families and pet lovers. The property is equipped with thoughtful amenities for children such as free cribs and a first aid kit, ensuring a safe and comfortable environment for all guests. With a pet policy that permits dogs and accommodates service animals, this hotel is an excellent option for those looking for a blend of comfort and convenience in their stay.

Where to stay near Cairo

For an unforgettable vacation experience, Cairo, Illinois offers a delightful mix of outdoor adventures and rich history. Stroll through the charming streets of Cairo, exploring its unique neighbourhoods, or enjoy family-friendly activities at local campgrounds. Just a stone’s throw away, discover the vibrant atmosphere of nearby cities, perfect for both relaxation and exploration. Whether you're soaking in the local culture or adventuring in nature, Cairo promises a memorable getaway.

  • Wickliffe: Located a mere 9.7km from Cairo, Wickliffe is a charming city that beckons travellers with its stunning outdoor scenery and romantic experiences. With visitor numbers peaking from March to April and August, this inviting locale offers a variety of recreational activities. Golf enthusiasts can enjoy local courses, while nature lovers can explore nearby lakes and the national state park. The serene forests surrounding Wickliffe provide the perfect backdrop for hiking and picnicking, making it an ideal spot for those seeking relaxation amidst nature.
  • Mound City: Also situated 9.7km from Cairo, Mound City is another appealing destination for outdoor adventurers and couples looking for a romantic getaway. With peak visitor seasons in March, July, and October, this city offers a plethora of activities including access to recreational parks and golf courses. Nature enthusiasts will appreciate the nearby forests, lakes, and urban parks, all waiting to be explored. Mound City’s blend of adventure and scenic beauty ensures a memorable experience for all who visit.
  • Wyatt: Just 11.3km from Cairo, Wyatt is a family-friendly city that offers a delightful mix of outdoor activities and urban charm. With peak travel periods from June to August, families can enjoy the local golf courses, dog parks, and urban parks that create a vibrant community atmosphere. Wyatt's event and conference venues make it an ideal spot for gatherings, while the accessible parks provide a great space for relaxation and fun. This city promises a well-rounded experience for visitors of all ages.

Things to do in Cairo

Shopping

Cairo offers a quaint shopping experience with local boutiques and souvenir shops. For a wider selection, if you're up for a drive, head to the nearby Town Square in Paducah or the Mall at 270 in Cape Girardeau, both offering a variety of retail options.

Recreation

In Cairo, the Riverfront Park offers a tranquil setting along the Mississippi River, ideal for leisurely strolls and picnics. For relaxation, visit a local spa that provides rejuvenating treatments and massages, ensuring a refreshing experience amid the charming surroundings.

Adventure

Cairo offers a unique blend of history and adventure. Explore the scenic Mississippi River by kayaking or fishing. Visit the nearby Trail of Tears State Park for hiking amidst stunning landscapes, or enjoy birdwatching at the confluence of the Ohio and Mississippi rivers, where nature thrives.

Nightlife

Explore the atmosphere at The Hangout, where you can enjoy live music and a vibrant crowd. For a relaxed evening, visit The Cairo CafƩ, serving up tasty bites and a selection of local brews. Don't miss the chance to mingle with friendly locals and discover the area's charm.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in and around Cairo

Cairo, Illinois, is an ideal destination for those seeking outdoor adventures and stunning scenery. Visitors can explore a variety of attractions, including national parks, nature reserves, and historic forts. Whether you're after cultural experiences or simply want to soak up the beautiful landscapes, Cairo offers plenty of opportunities to enjoy the great outdoors and discover its rich history.

  • Columbus-Belmont State Park: Located 27.4km from Cairo, this national park offers stunning outdoor scenery and adventure opportunities. Visitors can enjoy hiking trails, picnic areas, and breathtaking views of the Mississippi River, making it a great spot for nature lovers.
  • Ballard Wildlife Management Area: Just 8.0km away from Cairo, this wildlife preserve is rich in history and is an affordable option for those keen on birdwatching and exploring natural habitats. The area is ideal for quiet reflection and observing wildlife in their natural setting.
  • Fort Defiance State Park: Situated within Cairo, this historic fort showcases local culture and history. The park features walking trails and informative displays, providing insight into the region’s past while offering lovely views of the confluence of the Mississippi and Ohio Rivers.

Best time to go to Cairo

The best time to visit Cairo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Cairo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Cairo falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighSlightly High
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

Flying into Cairo, Illinois, is convenient with several nearby airports. Paducah, KY (PAH-Barkley Regional) is 37.0km away, where you can find quality accommodation such as The Respite Bed and Breakfast, 14.5km from the airport, and Harrah's Metropolis Hotel & Casino, 9.7km away. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 41.8km from Cairo, with options like Drury Plaza Hotel, 9.7km from the airport. Additionally, Veterans Airport of Southern Illinois (MWA) is 83.7km away, featuring hotels like Drury Inn & Suites Marion, just 3.2km from the airport. Each location offers various transport services to facilitate your travel to Cairo.

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveller data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Two other choices for your stay in the area are Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston. See all available top hotels, or vacation rentals in Cairo.
What are some of the best holiday rentals that Cairo has to offer?
Wandering the wineries or hitting the hills? We got you! Come stay!: This holiday home rental outside of Cairo is located in a rural location, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer, including the restaurants, entertainment choices and riverfront. This city also attracts tourists with its small-town vibe. There are 28 hotels and other accommodation options in the surrounding area. Find out more about Cairo.
What should I do while I'm visiting Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Take a look at what more there is to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.

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