All hotels in Southeast Missouri, Missouri
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
All hotels in Southeast Missouri, Missouri
We have found 582 Southeast Missouri Hotels
- Baymont Inn and Suites by Wyndham Farmington, MO
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Motel 6 Poplar Bluff, MO
- The Farmstead Hotel
- Best Western Plus Sikeston
- Tru By Hilton Cape Girardeau
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Drury Inn & Suites Sikeston, MO
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Hampton Inn Cape Girardeau I 55 East
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Poplar Bluff
- Super 8 by Wyndham Farmington
- Pear Tree Inn Sikeston
- Drury Inn & Suites Hayti Caruthersville
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Super 8 by Wyndham Bonne Terre
- Hampton Inn Poplar Bluff
- Days Inn and Suites by Wyndham Sikeston
- Fairfield by Marriott Inn & Suites Sikeston
- Dexter Inn
- Crown Pointe Lodge, BW Signature Collection
- Quality Inn Charleston - Sikeston
- Black River Motel and Restaurant
- Century Casino & Hotel Caruthersville
- Super 8 by Wyndham Charleston/Sikeston East MO
- Econo Lodge
- Country Yard Inn and Suite
- Silo Farm Haus- located in the heart of wine country!
- New Orleans Inn Portageville
- Super 8 by Wyndham Kennett
- Madison Inn Lodge
- OYO Malden Airport Inn
- Shepherd Mountain Inn
- Econo Lodge Dexter
- Super 8 By Wyndham Marston
- OYO Hickory House Inn
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Travel Inn
- Wilderness Lodge
- Echo Bluff State Park
- EC Reed's Mercantile and Hotel
- Fort Davidson Hotel
- Rockwood Inn
- La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau
- The Queen Bee Farm Stay/Hot tub
- TownePlace Suites by Marriott Sikeston
- The Lodge @ Stormy Mountain Ranch Close drive to Emience and surrounding springs
- Arcadia Academy
- Eagle Inn Charleston
- Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Let Expedia take you to the best Hotels in Southeast Missouri. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.