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Top Mountain Southeast Minnesota Hotels

The Plaza Hotel & Suites Winona

1025 Highway 61 E Winona MN

2 hours drive from Mayo Clinic

Stay at this hotel in Winona. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. Popular attractions ...

8.6/10 Excellent! (1,000 reviews)

This motel is very well maintained, very clean. Staff was always very friendly and polite. Warm and comfortable rooms

Reviewed on 5 Jan 2026

Holiday Inn Express & Suites Winona by IHG

1128 Homer Rd Winona MN

2 hours drive from Mayo Clinic

Stay at this family-friendly hotel in Winona. Enjoy free breakfast, free parking and a 24-hour fitness centre. Our guests praise the helpful staff in their reviews. ...

9/10 Wonderful! (903 reviews)

Breakfast was amazing! Hot tub, pool and sauna were incredible!

Reviewed on 4 Jan 2026

See all 940 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.