Photo by Southernmost Illinois Tourism Bureau

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Top Luxury Southwest Illinois Hotels

Super 8 by Wyndham Troy IL/St. Louis Area

910 Edwardsville Rd Troy IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their ...

8/10 Very Good! (1,006 reviews)

"Nice clean rooms."

Reviewed on 22 June 2026

Super 8 by Wyndham Mt. Vernon IL

401 S 44th St Mount Vernon IL

2 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.8/10 Good! (1,003 reviews)

"Bed was comfy, pillows were above average from most hotels. Bathroom seemed recently updated and clean. However… carpet was HORRID!! Very old and shoes stuck to it slightly when walking on it… Also, the sheets on one of the beds had a couple stains on them that looked like blood, and it looked like ..."

Reviewed on 21 June 2026

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL

5 min drive from Southern Illinois University

Stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.4/10 Good! (1,003 reviews)

"Property was good for a one night stay while we were traveling through. All was good but the breakfast was a little sparse. Not much to choose from."

Reviewed on 20 June 2026

See all 758 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.