Santa Cruz Island Luxury Holidays 2026

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Top Luxury Santa Cruz Island Hotels

Hotel Ninfa

Settlers and Thomas de Berlanga Puerto Ayora Galapagos

13 min walk from Charles Darwin Research Station

Stay at this hotel in Puerto Ayora. Enjoy free breakfast, room service and a 24-hour front desk. Popular attractions Malecon and Gus Angermeyer Ferry Terminal ...

Blu Galapagos Sustainable Waterfront Lodge

Ave. Charles Darwin S/n Y Piquero Puerto Ayora Galapagos

6 min walk from Charles Darwin Research Station

Stay at this business-friendly hotel in Puerto Ayora. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their ...

Finch Bay Galapagos Hotel

Barrio Punta Estrada Puerto Ayora Galapagos

16 min walk from Charles Darwin Research Station

Stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free Wi-Fi and a full-service spa. Popular attractions Playa de los Alemanes and Malecon are ...

See all 224 properties in Santa Cruz Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.