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Top Adventure Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (2,228 reviews)

"Good"

Reviewed on 23 July 2026

Willow Inn Suites Rochester

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway Rochester MN

6 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the restaurant and the helpful ...

8.8/10 Excellent! (1,008 reviews)

"My experience at the Hotel Indigo was fantastic. Sandy was absolutely amazing:! She went above and beyond to made an already stressful trip so comfortable and truly made us feel at home. Larry was also amazing, making sure that my daughter and I got to all her appointments on time, and back to the ..."

Reviewed on 24 July 2026

See all 924 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.