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Top Adventure Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.4/10 Very Good! (2,138 reviews)

"1"

Reviewed on 3 June 2026

Willow Inn Suites Rochester

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...

7.4/10 Good! (1,000 reviews)

"Safe, clean, friendly and great price."

Reviewed on 17 Apr 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway Rochester MN

6 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the restaurant and the helpful ...

8.8/10 Excellent! (1,010 reviews)

"Very clean & comfortable and the staff were super helpful in shipping my lost items!"

Reviewed on 7 June 2026

See all 932 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.