Photo by Southernmost Illinois Tourism Bureau
Luxury Hotels & Resorts in Southern Illinois from NZ$194
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois Luxury Hotels
Our top choices for Southern Illinois luxury hotels
8.4 out of 10, Very good, (833 reviews)
- Plush beds and serene pool define luxury at Mt. Vernon retreat where spa awaits after exploration.
The price is NZ$248
includes taxes & fees
30 May - 31 May
9.4 out of 10, Exceptional, (455 reviews)
- Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
The price is NZ$223
includes taxes & fees
25 May - 26 May
8.2 out of 10, Very good, (1,001 reviews)
- Upscale St. Louis hotel offers steakhouse, indoor pool, and 24-hour fitness centre.
The price is NZ$231
includes taxes & fees
14 June - 15 June
10.0 out of 10, Exceptional, (9 reviews)
The price is NZ$187
includes taxes & fees
2 June - 3 June
9.4 out of 10, Exceptional, (1,001 reviews)
- Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is NZ$706
includes taxes & fees
24 May - 25 May
9.2 out of 10, Wonderful, (568 reviews)
- Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
The price is NZ$991
includes taxes & fees
24 May - 25 May
8.6 out of 10, Excellent, (1,005 reviews)
- Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is NZ$377
includes taxes & fees
18 June - 19 June
9.2 out of 10, Wonderful, (918 reviews)
The price is NZ$236
includes taxes & fees
25 May - 26 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
Explore a world of travel with Expedia
- Dix Hotels
- Marion County Hotels
- Christopher Hotels
- Flora Hotels
- Albion Hotels
- Sims Hotels
- Odin Hotels
- Farina Hotels
- Percy Hotels
- Aviston Hotels
- Cisne Hotels
- Tamaroa Hotels
- Centralia Hotels
- Noble Hotels
- Bonnie Hotels
- Elkville Hotels
- Carlyle Hotels
- Harrisburg Hotels
- Ina Hotels
- Johnston City Hotels
- Belle Rive Hotels
- Creal Springs Hotels
- Hotels near Rainbow Ranch Petting Zoo
- Nashville Hotels
- Equality Hotels
- Enfield Hotels
- Carbondale Hotels
- Benton Hotels
- Marion Hotels
- Carterville Hotels
- Galatia Hotels
- Buckner Hotels
- Hotels near Bell Tower Park
- Whittington Hotels
- Wolf Creek Hotels
- Hotels near Lake of Egypt
- Sesser Hotels
- Mount Vernon Hotels
- Fairfield Hotels
- West Frankfort Hotels
- Okawville Hotels
- Patoka Hotels
- Ava Hotels
- New Haven Hotels
- Herrin Hotels
- Sparta Hotels
- Du Quoin Hotels
- Hoyleton Hotels
- Caravan Parks in Du Quoin
- Resort in Southern Illinois
- Cabin Rentals in Southern Illinois
- Motels in Southern Illinois
- Motels in Sparta
- Apartments in Ava
- Motels in Dix
- Cabin Rentals in Wolf Creek
- Motels in Marion
- Cabin Rentals in Benton
- Cheap Hotels in Grayville
- Spa Hotels in Carbondale
- Luxury Hotels in Marion
- Pet Friendly Hotels in Mount Vernon
- Hilton Hotels in Whittington
- Marriott Hotels & Resorts in Carterville
- Herald Holidays
- William Jennings Bryan Boyhood Home and Museum
- Herrin Holidays
- Carmi Holidays
- Sih Medical Group
- Heartland Regional Medical Center
- Lake of Egypt
- Christopher Holidays
- Du Quoin Holidays
- Sparta Country Club
- King City Square Shopping Center
- Ken Gray Presidential Hall of Fame
- Salem Fairgrounds
- Opdyke Holidays
- Visit West Frankfort
- Visit Johnston City
- Visit Mount Vernon
- Visit Maunie
- Visit Sesser
- Visit Cisne
- Visit Herrin
- Visit Wertenberg
- Visit Wamac
- Car hire in Avis Fort Lauderdale Cruiseport Shuttle-2520 Miami Rd
- Dollar Rental Cars in Southern Illinois
- Global Rent a Car Rental Cars in Southern Illinois
- Hertz Rental Cars in Southern Illinois
- Enterprise Rental Cars in Benton
- Hertz Rental Cars in Southwest Illinois
- Car hire Mount Vernon
- Car hire Carmi