A forested valley with autumn foliage, a rocky cliff, and a sunset.

Luxury Hotels & Resorts in Southern Illinois from NZ$134

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Luxury Hotels

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sept - 6 Sept

Our top choices for Southern Illinois luxury hotels

1. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
  • Plush beds and serene pool define luxury at Mt. Vernon retreat where spa awaits after exploration.
NZ$258
includes taxes & fees
30 Aug - 31 Aug
DoubleTree by Hilton Mt. Vernon

2. DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
Eastport
  • Upscale St. Louis hotel offers steakhouse, indoor pool, and 24-hour fitness centre.
NZ$249
includes taxes & fees
21 Sept - 22 Sept
DoubleTree by Hilton Collinsville - St. Louis

3. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
NZ$214
includes taxes & fees
25 Aug - 26 Aug
Walker's Bluff Casino Resort

4. Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
Charleston
NZ$218
includes taxes & fees
1 Sept - 2 Sept
Charleston House Bed & Breakfast Inn

5. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
NZ$733
includes taxes & fees
24 Aug - 25 Aug
Four Seasons Hotel St Louis

6. Moonrise Hotel

Moonrise Hotel
Delmar Loop
  • Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
NZ$316
includes taxes & fees
3 Sept - 4 Sept
Moonrise Hotel

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
NZ$1,072
includes taxes & fees
20 Sept - 21 Sept
The Ritz-Carlton, St. Louis

8. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
NZ$412
includes taxes & fees
31 Aug - 1 Sept
The Royal Sonesta Chase Park Plaza St. Louis

9. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
  • Experience grandeur in a historic hotel with 7 restaurants, seasonal pool, and concierge services in city centre St. Louis.
NZ$290
includes taxes & fees
20 Sept - 21 Sept
St. Louis Union Station Hotel, Curio Collection by Hilton

10. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
NZ$316
includes taxes & fees
30 Aug - 31 Aug
Live by Loews - St.Louis
View all properties

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Easy parking, dinner and breakfast great"
Fiona 1-night trip
Posted 1 day ago
Drury Inn & Suites St. Louis Fairview Heights

Explore a world of travel with Expedia