A forested valley with autumn foliage, a rocky cliff, and a sunset.

Casino Hotels & Resorts in Southern Illinois from NZ$116

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Casino Hotels

Our top choices for Southern Illinois hotels with a casino

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

1. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,868 reviews)
"Nice comfortable stay"
United States
Mei
The price is NZ$225
includes taxes & fees
17 Nov - 18 Nov
Drury Plaza Hotel Mt. Vernon
A modern building with a covered entrance, large windows, and a clear sky.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,002 reviews)
"Clean room, the staff was great. The breakfast was good. The parking was convenient."
United States
Kevin
The price is NZ$218
includes taxes & fees
11 Dec - 12 Dec
Holiday Inn Express & Suites Mount Vernon by IHG
An outdoor patio with wicker furniture, a central table, and a view of a grassy field and trees.

3. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,088 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is NZ$241
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.

4. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (736 reviews)
"The room & lobby had a musty smell. Shower was small. Breakfast was ok"
United States
Paul
The price is NZ$223
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

5. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (725 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is NZ$146
includes taxes & fees
13 Dec - 14 Dec
Quality Inn Mount Vernon, IL
A breakfast buffet with various pastries, a bowl of oranges, and a waffle batter dispenser.

6. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
8.0 out of 10, Very good, (1,012 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is NZ$149
includes taxes & fees
23 Nov - 24 Nov
Super 8 by Wyndham Mt. Vernon IL
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

7. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (691 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is NZ$280
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus Centralia Hotel & Suites
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.

8. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (910 reviews)
"Loved the onsite bar and the location of the hotel"
United States
Tammi
The price is NZ$259
includes taxes & fees
26 Nov - 27 Nov
DoubleTree by Hilton Mt. Vernon
A spacious lobby with a stone fireplace, a sofa, and a coffee table.

9. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,000 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is NZ$153
includes taxes & fees
1 Dec - 2 Dec
SureStay Hotel by Best Western Whittington Rend Lake
A cozy living room with a stone fireplace, leather sofas, and a flat-screen TV.

10. Cobblestone Inn & Suites - Altamont

Cobblestone Inn & Suites - Altamont
2.5 star property
Altamont
9.6 out of 10, Exceptional, (966 reviews)
"Clean and quiet room. Very relaxing after a long day of driving. Highly recommend."
United States
Dee
The price is NZ$206
includes taxes & fees
14 Dec - 15 Dec
Cobblestone Inn & Suites - Altamont
A modern lobby with a stone accent wall, a flat-screen TV, orange armchairs, a dark sofa, and a colorful rug.

11. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.2 out of 10, Very good, (1,000 reviews)
"It is an older property but I thought it was very nice"
United States
Colleen
The price is NZ$142
includes taxes & fees
22 Nov - 23 Nov
Quality Inn & Suites Vandalia near I-70 and Hwy 51
A buffet with various food options, including omelets and other dishes.

12. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (811 reviews)
"Nice place"
United States
Kim
The price is NZ$211
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Salem by IHG
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

13. Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (461 reviews)
"Worked well for our short stay."
United States
Steven
The price is NZ$235
includes taxes & fees
15 Nov - 16 Nov
Best Western U. S. Inn
A brick building entrance with a glass door featuring a reflective pattern and a mat with the text "MAKING YOU HAPPY MAKES US HAPPY."

14. Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (804 reviews)
"The property was very clean even just staying a quick overnight traveling the room felt very comfortable."
United States
Scott
The price is NZ$253
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites Effingham
A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.

15. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,002 reviews)
"Very nice stay!!!"
United States
Steve
The price is NZ$209
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn & Suites by Wyndham Effingham
A spacious room with large windows, a fireplace, and a patterned carpet.

16. Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
2.0 star property
Mount Vernon
6.6 out of 10, (1,000 reviews)
"Checking in was very easy and quick. I have no complaints."
United States
Howard
The price is NZ$126
includes taxes & fees
22 Nov - 23 Nov
Days Inn by Wyndham Mount Vernon
An outdoor seating area with a fire pit, surrounded by wooden chairs and a view of a sunset over a landscaped garden.

17. Best Western Plus Parkside Inn & Suites

Best Western Plus Parkside Inn & Suites
2.5 star property
Olney
9.8 out of 10, Exceptional, (399 reviews)
"Very clean and friendly staff."
United States
Lynda
The price is NZ$253
includes taxes & fees
8 Dec - 9 Dec
Best Western Plus Parkside Inn & Suites
A hotel room with two beds, a desk, a chair, a TV, and a small plant.

18. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
2.0 star property
Mount Vernon
7.2 out of 10, Good, (1,002 reviews)
"Good place to stay, we were traveling and the price was great, clean room, great staff we were very comfortable"
United States
Karalee
The price is NZ$135
includes taxes & fees
6 Dec - 7 Dec
Rodeway Inn Mount Vernon, IL
An outdoor patio area with a fire pit, seating, and a covered section.

19. Home2 Suites By Hilton Effingham

Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (67 reviews)
"The hotel was clean and room was fantastic in every way."
United States
Steve
The price is NZ$256
includes taxes & fees
6 Dec - 7 Dec
Home2 Suites By Hilton Effingham
A hotel with a covered entrance, stone pillars, and a clear sky.

20. Cobblestone Hotel & Suites - Newton

Cobblestone Hotel & Suites - Newton
2.5 star property
Newton
9.2 out of 10, Wonderful, (365 reviews)
"Nice place"
United States
Suzanne
The price is NZ$233
includes taxes & fees
19 Nov - 20 Nov
Cobblestone Hotel & Suites - Newton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Explore a world of travel with Expedia