Photo by Southernmost Illinois Tourism Bureau

Search Guest Houses in Southern Illinois

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Check prices for these dates

Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec
In one month
9 Jan - 11 Jan
In two months
6 Feb - 8 Feb

Our top choices for Southern Illinois guest houses

Exterior
Riverview Mansion Hotel

Riverview Mansion Hotel

Riverview Mansion Hotel
3.0 star property
Golconda
8.6 out of 10, Excellent, (26)
"Historic also needs to be cleaned"
United States
jolanta
Riverview Mansion Hotel
Outdoor dining
Modern 2BR Lake Suite • Dock & Firepit

Modern 2BR Lake Suite • Dock & Firepit

Modern 2BR Lake Suite • Dock & Firepit
Marion
10.0 out of 10, Exceptional, (16)
"This was a cozy and convenient place to stay for our Garden of the Gods day trip."
United States
Joshua R.
The price is NZ$470
includes taxes & fees
14 Dec - 15 Dec
Modern 2BR Lake Suite • Dock & Firepit
Fridge, microwave, oven, stovetop
Thanksgiving Dates Available for the First Time in Years!

Thanksgiving Dates Available for the First Time in Years!

Thanksgiving Dates Available for the First Time in Years!
Carbondale
9.6 out of 10, Exceptional, (51)
"Very clean and beautifully decorated house. Well maintained property! "
United States
Alla H.
The price is NZ$1,312
includes taxes & fees
5 Jan - 6 Jan 2026
Thanksgiving Dates Available for the First Time in Years!
Fridge, microwave, coffee/tea maker, cookware/dishes/utensils
Cozy, Fun, and One-Of-A-Kind!

Cozy, Fun, and One-Of-A-Kind!

Cozy, Fun, and One-Of-A-Kind!
Shaw
9.4 out of 10, Exceptional, (118)
"Cute place - exactly what we needed for this trip to St. Louis. "
United States
Angela L.
The price is NZ$245
includes taxes & fees
18 Dec - 19 Dec
Cozy, Fun, and One-Of-A-Kind!
Front of property
Grand Center Inn

Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (70)
"Great! "
United States
mike
The price is NZ$321
includes taxes & fees
15 Dec - 16 Dec
Grand Center Inn
Interior
Charming Home with Country Views

Charming Home with Country Views

Charming Home with Country Views
Grafton
10.0 out of 10, Exceptional, (39)
"Friends weekend trip. Great location, as advertised, smooth check in/out process. "
United States
deb r.
The price is NZ$543
includes taxes & fees
23 Dec - 24 Dec
Charming Home with Country Views
TV, video games
In the center of all Historic Main Street has to offer

In the center of all Historic Main Street has to offer

In the center of all Historic Main Street has to offer
Grafton
7.0 out of 10, Good, (2)
"Such a great location! Very clean & cute house!"
United States
Janelle C.
The price is NZ$1,075
includes taxes & fees
21 Dec - 22 Dec
In the center of all Historic Main Street has to offer
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

10/10 Excellent
"The room was spacious and clean. Bed was pretty comfortable. Hot breakfast food was welcomed."
Brandon 2-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Effingham

Find out more about Southern Illinois

Southern Illinois Guest Houses information

Number of reviews
317
Accommodation
4 Guest Houses
Lowest Price
NZ$245
Highest Price
NZ$1,312

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