Photo by Ryan Coleman

Search Sikeston hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sikeston hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
This centrally located hotel offers convenient access to restaurants and shopping. Take advantage of the indoor pool and fitness centre after exploring nearby Cape Splash Family Aquatic Centre. Free breakfast, WiFi, and parking enhance your stay with attentive staff ready to assist.

"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is NZ$177
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19)
Located just minutes from popular attractions like Show Me Centre and Isle Casino, this hotel offers free WiFi and parking. Relax in the garden after exploring Cape Girardeau's highlights, with convenient access to the municipal airport.

"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is NZ$296
includes taxes & fees
4 Jan - 5 Jan
Rockwood Inn

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (480)
Located near Riverfront Park and Isle Casino, this business-friendly hotel offers exciting gaming, 2 restaurants including Beacon 53 for American cuisine, plus free WiFi and parking for convenient exploration of Cape Girardeau.

" Excellent stay. Will come again"
United States
joydeep
The price is NZ$186
includes taxes & fees
2 Jan - 3 Jan
The Riverview

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (471)
Wake up to Mississippi River views at this city centre hotel, steps from Riverfront Park and Shawnee National Forest. After exploring, return to The Bistro for American cuisine or unwind at the bar. The 24-hour fitness centre and in-room refrigerators enhance your stay.

"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is NZ$224
includes taxes & fees
25 Jan - 26 Jan
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
Located near Shawnee National Forest and Mississippi River, this hotel offers complimentary breakfast, WiFi and parking. Unwind in the indoor pool, utilise the fitness centre or relax on the terrace. Clean rooms feature refrigerators and microwaves.

"Excellent stay"
United States
Christina
The price is NZ$206
includes taxes & fees
8 Jan - 9 Jan
Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (145)
Enjoy free continental breakfast and complimentary parking at this modern Cape Girardeau retreat. The indoor pool offers year-round swimming, while Fort D Historic Site and Cape Splash Family Aquatic Centre are just minutes away.

"Lovely staff clean hotel comfortable beds "
United States
Kastriot
The price is NZ$171
includes taxes & fees
8 Jan - 9 Jan
Fairfield Inn & Suites by Marriott Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1005)
Explore Shawnee National Forest from this Cape Girardeau hotel offering complimentary breakfast, WiFi, and parking. Enjoy the indoor pool and spa pool after a day out, or dine at The Southerner restaurant. Each room includes handy refrigerators and microwaves.

"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
United States
Michael
The price is NZ$175
includes taxes & fees
5 Jan - 6 Jan
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.

"Great place. Friendly staff clean"
United States
Jeff
The price is NZ$179
includes taxes & fees
5 Jan - 6 Jan
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
Wake up to complimentary breakfast at this quiet retreat near Shawnee National Forest. Guests love the peaceful atmosphere, helpful staff, and convenient location close to Cape Splash Family Aquatic Centre. Free WiFi and parking enhance the overall value.

"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is NZ$136
includes taxes & fees
6 Jan - 7 Jan
Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
Conveniently located near Shawnee National Forest, this Cape Girardeau hotel offers morning swims in the indoor pool and energising workouts at the fitness centre. Enjoy free breakfast before exploring nearby nature attractions.

"It was a nice stay"
United States
Douglas
The price is NZ$176
includes taxes & fees
11 Jan - 12 Jan
Tru By Hilton Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1005)
Walking distance to restaurants and shops, this peaceful hotel offers complimentary breakfast, WiFi, and parking. Swim year-round in the indoor pool or unwind in the spa pool after exploring nearby attractions like Cape Splash Family Aquatic Centre.

"Awesome stay!"
United States
Breckin
The price is NZ$175
includes taxes & fees
5 Jan - 6 Jan
Drury Inn & Suites Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (886)
"Room was clean and spacious."
United States
George
The price is NZ$146
includes taxes & fees
11 Jan - 12 Jan
Candlewood Suites Cape Girardeau by IHG

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (689)
Escape to this Cape Girardeau hotel with an outdoor pool, just minutes from Shawnee National Forest. Enjoy free breakfast, WiFi, and parking. The helpful staff ensures a pleasant stay while nature attractions and the Mississippi River await nearby.

"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is NZ$115
includes taxes & fees
22 Jan - 23 Jan
Quality Inn Cape Girardeau North

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (681)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is NZ$151
includes taxes & fees
4 Jan - 5 Jan
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (456)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness centre. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.

"Very clean and super friendly staff!"
United States
Katherine
The price is NZ$200
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1005)
Located in Sikeston, this hotel offers an indoor pool for relaxing swims after a day of exploring. Near Central Park and the Sikeston Depot Museum, guests praise the delicious free breakfast and attentive service.

"Great stay, everything was clean and comfortable. "
United States
Charles
The price is NZ$157
includes taxes & fees
25 Jan - 26 Jan
Best Western Plus Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
Discover comfort at this Sikeston hotel with an indoor pool and fitness centre. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.

"Stay was excellent "
United States
Kourtney
The price is NZ$182
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
This quiet retreat offers an indoor pool for morning swims and a relaxing spa pool to end your day. Clean rooms provide a peaceful atmosphere near Litz Park and Lazy L Safari Park, with free breakfast, WiFi, and parking to enhance your stay.

"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is NZ$152
includes taxes & fees
4 Jan - 5 Jan
Drury Inn & Suites Jackson MO

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
This peaceful hotel offers a quiet atmosphere just minutes from Shawnee National Forest and Cape Splash Family Aquatic Centre. Nearby restaurants and stores enhance convenience while helpful staff ensure a comfortable stay with free WiFi and daily housekeeping.

"Nice place for a stay at a reasonable price."
United States
Arthur
The price is NZ$136
includes taxes & fees
5 Jan - 6 Jan
Pear Tree Inn Cape Girardeau Near the Medical Center

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (5)
"Great stay "
United States
Ashley
The price is NZ$205
includes taxes & fees
9 Jan - 10 Jan
Hampton Inn By Hilton Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Sikeston attractions

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap accommodation in Sikeston

Frequently asked questions

Where is the best place to stay in Sikeston?
Fairfield Inn & Suites by Marriott Sikeston is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Other top choices based on reviews include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Sikeston.
What are some of the best holiday rentals that Sikeston has to offer?
Beautiful location in the secluded woods: This holiday home rental outside of Sikeston offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.
What's the best family accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your family trip. Find more child-friendly accommodations in Sikeston.
What's the best LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best dog-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Hampton Inn Sikeston and Pear Tree Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
What are some hotels with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. TownePlace Suites by Marriott Sikeston is another choice with an on-site pool. View all hotels with pools in Sikeston.
What is staying in Sikeston like?
Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.
What is there to see in Sikeston?
A couple of favourite places to visit are Sikeston Depot Museum and Central Park. You'll also find River Ridge Winery and Front Street Studio & Art Gallery in the area. Take a look at what more there is to see and do in Expedia's Sikeston guide.
What's the seasonal weather in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

Explore a world of travel with Expedia