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The best area to stay in Santa Cruz is Equipetrol, known for its modern amenities and convenience.


Equipetrol is the city's most upscale district, characterised by wide avenues, contemporary architecture, and a well-maintained appearance. It's home to many of Santa Cruz's best hotels, restaurants, and shopping centres. The area is largely centred around Avenida San Martín and its intersecting streets, offering a straightforward layout that's easy to navigate.


Couples looking for a sophisticated and comfortable stay will find Equipetrol ideal. The neighbourhood offers a wide array of high-quality dining experiences, from international cuisine to local gourmet options. You'll also find plenty of stylish bars and cafes for evening enjoyment, all within a pleasant walking distance from most accommodations.


For business travellers, Equipetrol is exceptionally convenient. Many corporate offices and convention centres are located here, making commutes short and simple.

Two of the best hotels in Santa Cruz that receive consistently high recommendations from travellers are the Novotel Santa Cruz De La Sierra and the Swissôtel Santa Cruz De La Sierra.


The Novotel Santa Cruz De La Sierra, with a 9.2 rating, is a luxury option known for its excellent restaurant and comfortable pillows. It also offers 24-hour room service, rainfall showerheads, and premium bedding.


Another highly recommended option is the Swissôtel Santa Cruz De La Sierra, which also has a 9.2 rating. Guests frequently praise its excellent facilities, good beds and showers, and great location. The hotel provides premium bedding, a poolside bar, and 24-hour room service. It is conveniently located near Ventura Mall, just 1.1 km away.

For families seeking excellent accommodation in Santa Cruz, the Novotel Santa Cruz De La Sierra, Camino Real Hotel, and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel are highly recommended.


The Novotel Santa Cruz De La Sierra, with an impressive 9.2 rating, caters to families. It provides a variety of children's amenities such as a dedicated children's club, a playground, and a children's pool. Families will also appreciate the connecting rooms and sofa beds available, alongside toys and cribs. Guests frequently mention the comfortable pillows and the excellent on-site restaurant.


Another superb choice is the Camino Real Hotel, rated 8.8. This hotel is particularly convenient, located just 0.2 km from Ventura Mall. It offers a children's pool, babysitting services, and a playground, along with child-friendly window designs for added safety. Customers consistently praise its excellent location and super helpful and kind staff.


The Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, with a 9.0 rating, is another fantastic option for families. It provides connecting rooms, free cribs, and a children's pool. Families can also benefit from free breakfast, including a buffet, and kids' meals. It is conveniently located 1.1 km from Ventura Mall, and guests often highlight its excellent location and friendly staff. Find more child-friendly accommodations in Santa Cruz

For highly-rated hotels in Santa Cruz, consider the Novotel Santa Cruz De La Sierra or the Marriott Santa Cruz de la Sierra Hotel.


The Novotel Santa Cruz De La Sierra, with an impressive 9.2 rating, offers a luxurious experience with features such as 24-hour room service, premium bedding, and rainfall showerheads. Guests often highlight the comfortable pillows and excellent restaurant. The hotel's Art Deco design adds a touch of elegance, and it is conveniently located within a shopping district.


Another excellent choice is the Marriott Santa Cruz de la Sierra Hotel, rated 9.0. This hotel provides spacious suites, executive rooms with lounge access, and rainfall showerheads. Guests frequently mention the great service. For those looking to enjoy some retail therapy, the Ventura Mall is just 0.8 km away. Find more luxury hotels in Santa Cruz

For an excellent spa experience in Santa Cruz, consider the Hotel Cortez or Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel.


The Hotel Cortez, with an impressive 9.2 rating, provides a full-service spa where guests can enjoy a variety of treatments, including massages. The spa also features a hot tub, steam room, and sauna, great for relaxation. Guests frequently highlight the kind staff.


Another highly-rated option is the Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, which has a 9.0 rating. This hotel offers extensive spa facilities, including hydrotherapy treatments, a steam room, and various treatment rooms for massages, facials, body scrubs, and manicures. Couples treatment rooms are also available. Guests consistently praise its excellent location and friendly staff.


The Marriott Santa Cruz de la Sierra Hotel, rated 9.0, also offers a full-service spa with massage treatments available daily. Guests often comment on the great service at this hotel.


Additionally, the Camino Real Hotel, with an 8.8 rating, includes a spa with massage treatment rooms, a steam room, and couples treatment rooms. Its location is often described as excellent, and the staff are noted for being super helpful and kind.


Finally, the Sun Hotel, rated 8.4, offers a range of spa services including steam room access, massages, facial treatments, reflexology, hot stone massages, and body treatments such as scrubs. Guests appreciate the good breakfast and helpful staff. See all spa hotels in Santa Cruz

For hotels in Santa Cruz offering complimentary breakfast, consider the Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, TRYP by Wyndham Santa Cruz, Cosmopolitano Hotel Boutique, and Hotel Cortez.


The Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, with a 9.2 rating, provides a free buffet breakfast that guests frequently describe as good. It also offers free Wi-Fi, free self-parking, and a 24-hour airport shuttle for added convenience.


Another excellent option is the Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, rated 9.0. This hotel provides a free buffet breakfast and boasts an onsite full-service spa with various treatments, including hydrotherapy, massages, and a steam room. It is also conveniently located approximately 1.9 km from the Municipal Library.


The TRYP by Wyndham Santa Cruz, with a 9.2 rating, also includes a free buffet breakfast. Guests appreciate the comfy beds and the nice pool. The hotel offers free Wi-Fi and free self-parking, and it is around 1.7 km from the Municipal Library.


The Cosmopolitano Hotel Boutique, rated 9.2, offers a free full breakfast and is praised for its convenient location. It is just 0.4 km from Plaza 24 de Septiembre and San Lorenzo Cathedral, and 0.5 km from La Recova Artisan Walk. Free Wi-Fi, free self-parking, and a 24-hour airport shuttle are also provided.


Finally, the Hotel Cortez, with a 9.2 rating, also includes a free buffet breakfast. Guests often praise the kind staff. The hotel offers free self-parking and free Wi-Fi, and it is located approximately 0.4 km from the Municipal Library.

For top pet-friendly hotels in Santa Cruz, consider the HOTEL OSHO, Ibis Santa Cruz DE LA Sierra, and Swissôtel Santa Cruz De La Sierra.


The HOTEL OSHO, with a 9.0 rating, welcomes both dogs and cats, providing food and water bowls for your convenience. Guests can also enjoy a complimentary continental breakfast during their stay. It is located approximately 1.6 km from Arenal Park.


Another excellent choice is the Ibis Santa Cruz DE LA Sierra, which boasts an impressive 9.6 rating. This hotel is also pet-friendly, allowing both dogs and cats. It is situated about 1.2 km from Arenal Park.


The Swissôtel Santa Cruz De La Sierra, rated 9.2, is another fantastic option for travellers with pets, accommodating both dogs and cats. This hotel also offers a 24-hour airport shuttle service, and guests frequently praise its excellent facilities and great location. It is conveniently located about 1.1 km from Ventura Mall. See more pet-friendly hotels in Santa Cruz

For top boutique hotels in Santa Cruz, consider the Novotel Santa Cruz De La Sierra or the TRYP by Wyndham Santa Cruz.


The Novotel Santa Cruz De La Sierra, with an impressive 9.2 rating, offers complimentary breakfast and free WiFi. Guests frequently comment on the comfortable pillows and the excellent on-site restaurant. It also provides a 24-hour airport shuttle service and free self-parking.


Another excellent option is the TRYP by Wyndham Santa Cruz, rated 9.2, which also provides free breakfast and free WiFi. Guests often praise the comfy beds and the nice pool. This hotel also offers a convenient 24-hour airport shuttle and free self-parking. See all boutique hotels in Santa Cruz

For excellent budget hotels in Santa Cruz, consider the Lido Hotel or the Hotel BY Armonia SCZ.


The Lido Hotel, with an outstanding 9.0 rating, is conveniently located just 0.5 km from Plaza 24 de Septiembre and the Municipal Library. Guests appreciate the complimentary buffet breakfast and free Wi-Fi, along with free self-parking.


Another great option is the Hotel BY Armonia SCZ, rated 8.4. This hotel offers a free 24-hour airport shuttle service and complimentary full breakfast, making it very convenient for travellers. Free Wi-Fi and free self-parking are also provided. View all budget hotels in Santa Cruz

For couples seeking a romantic stay in Santa Cruz, consider Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel or Chairú Eco Hotel.


The Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, with a 9.0 rating, offers an array of spa facilities superb for couples, including hydrotherapy treatments, a steam room, and even dedicated couples' treatment rooms. Some rooms also feature balconies, providing a nice private space for relaxation.


Another excellent choice for couples is the Chairú Eco Hotel, which boasts an impressive 9.6 rating. This hotel provides premium bedding for a comfortable stay and offers special couples' dining experiences, superb for a memorable evening together. Some rooms also include balconies. See all romantic hotels in Santa Cruz

For hotels in Santa Cruz located conveniently near Ventura Mall, consider the Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, or Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel.


The Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, with an excellent 9.2 rating, is particularly close to Ventura Mall, just 0.7 km away. Guests frequently praise the free and delicious breakfast, the clean rooms, and the friendly staff. It also offers a free airport shuttle and free self-parking, making it a very convenient option.


Another excellent choice is the Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, rated 9.0. It is located 1.1 km from Ventura Mall and provides a complimentary breakfast, including a buffet option. Guests often highlight the excellent location and the friendly staff.

For hotels near Santa Cruz (SRZ-El Trompillo) that are family-friendly, consider the Cosmopolitano Hotel Boutique or the Hotel LP Santa Cruz Centro.


The Cosmopolitano Hotel Boutique, with an excellent 9.2 rating, is a great option and is located just 1.7 km from the airport. It offers a free 24-hour airport shuttle, free full breakfast, and free WiFi. Families will appreciate amenities such as connecting rooms, child-friendly window design, and free cots.


Another suitable choice is the Hotel LP Santa Cruz Centro, rated 8.0, which is even closer to the airport at just 0.8 km away. This hotel also provides a free 24-hour airport shuttle service and free WiFi. Additionally, guests benefit from free parking.

The best time to visit Santa Cruz is during the dry season, which runs from May to October.


The dry season offers consistently pleasant weather, with lower humidity and less rainfall, making it ideal for exploring the city and its surroundings comfortably. You'll find it easier to enjoy outdoor activities and sightseeing without the interruption of heavy downpours.


For those planning to visit the nearby national parks, like Amboró, the dry season is particularly beneficial. The trails are more accessible, and wildlife spotting tends to be better when the weather is stable. This period is great for adventurers and nature enthusiasts looking to make the most of their outdoor excursions.


While the wet season (November to April) can bring lush greenery, it also comes with higher humidity and more frequent rain, which can sometimes disrupt travel plans.

You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to ‘My Trips’ and selecting your reservation. To find flexible deals, filter your search by ‘Fully refundable property’ for hotels in Santa Cruz.

One Key™—Expedia’s free travel rewards programme—gives you instant access to discounts with Member Prices on Santa Cruz hotels. Plus, you’ll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Prices for hotels in Santa Cruz often vary, but you can find a great deal from NZ$28 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by ‘Price: low to high’ for our cheapest rates.