Santa Cruz Holidays
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Our guide on where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Equipetrol
When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Municipal Library, some noteworthy sights in the nearby area.
Centro Histórico
3 out of top 10 points of interest in this area
If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.
Hamacas
When in Hamacas, you can plan a visit to Las Brisas Shopping Center and Santa Cruz Zoo, some noteworthy sights in the nearby area.
Zona Sur (South Zone)
Though Zona Sur (South Zone) may not have many top sights, you can venture to the surrounding area to see attractions like Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre.
Urubó
While there might not be top attractions in Urubó, you can explore the larger area and discover places like Guembe Biocenter and Ventura Mall.
Santa Cruz Holiday
Our pick of the best Santa Cruz Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
NZ$74
24 Oct - 25 Oct
9.4/10 Exceptional! (155 reviews)
"Amazed with the breakfast area,small but plenty of good food. Room small but clean,need to improve in amenities like soaps and lotions. Overall this place will be a five star hotel for the bolivian standars."
Reviewed on 18 Oct 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
NZ$239
7 Nov - 8 Nov
9/10 Wonderful! (416 reviews)
"Perfect place while in Santa Cruz! Comfortable and relaxed setting. 100%"
Reviewed on 18 Oct 2026
Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
NZ$187
1 Nov - 2 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
San Lorenzo Cathedral
9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
Ventura Mall
9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
Guembe Biocenter
8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
Santa Cruz Zoo
8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
Cine Center
8.0/10 (53 reviews)
This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping centre and diverse dining options in the food court.
Blacutt Square
8.2/10 (19 reviews)
Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavours from vendors along the northern edge while children play in the well-equipped playground areas.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernised facilities and vibrant Santa Cruz culture.
What to do in Santa Cruz
4D/3N Expedition: Che Guevara Route - Disconnect from the World
NZ$1,396
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
NZ$523
per adult
Santa Cruz: 2-day tour of the Che Guevara route in Bolivia
NZ$1,142
per adult
Frequently asked questions
How much does a Santa Cruz holiday package cost?
You'll find cheap prices on Expedia for your Santa Cruz break. However, a range of factors like the hotel choice, length of stay and season will determine how much your holiday to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, April and May are the best times to look for cheap Santa Cruz holiday packages. Opting to travel in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to tick off the main sights during your Santa Cruz holiday. However, if you prefer to have some time to kick back or take day tours, think about extending your itinerary.
Is it worth booking a holiday package to Santa Cruz?
Santa Cruz is a good holiday destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or getting away with friends, a Santa Cruz holiday promises a good time for everyone.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some tempting Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your holiday package as early as possible.
Is it cheaper to book a Santa Cruz holiday as a package?
You can enjoy significant savings on your Santa Cruz escape by booking a personalised holiday package. Click on the "Package" heading, then enter your travel dates and destination to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a holiday package to Santa Cruz?
If you're considering an impromptu Santa Cruz adventure, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Cruz?
- Choose your dates: What you want to do in Santa Cruz and your favourite season will help you decide when to get away.
- Work out your budget: Make sure you have enough money to pay for everything from transportation and dining out to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santa Cruz.
- Work out your trip length: Consider how much time you want to spend discovering Santa Cruz. Plan your days so you can get to all the experiences and attractions you're interested in without rushing.
- Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose a Santa Cruz holiday package that brings all your bookings together.
Explore a world of travel with Expedia
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
