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Our top choices for Santa Cruz hotels

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Stylish Santa Cruz apartments with outdoor pool and private balconies.
"Clean room, great staff "
Canada
Peter
The price is NZ$91
2 Mar - 3 Mar
AMERICA APARTMENTS

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (106 reviews)
  • cleanliness
    Experience a tropical retreat with pools, kids' club, and luxury amenities in Bolivia.
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is NZ$174
20 Mar - 21 Mar
Novotel Santa Cruz De La Sierra

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (343 reviews)
  • cleanliness
    Relaxing oasis near Viru Viru International with massage and pool amenities.
"Awesome place "
Canada
John
The price is NZ$161
20 Feb - 21 Feb
Sun Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (360 reviews)
  • cleanliness
    Unwind in Santa Cruz's lush oasis with pool bar and on-site spa services.
"Welcoming clean rooms, friendly staff, continental breakfast with natural drinks "
United States
Victor
The price is NZ$225
14 Mar - 15 Mar
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (263 reviews)
  • cleanliness
    Luxurious stay near Ventura Mall with rooftop dining and free amenities.
"Nice hotel "
United States
Narciso Lorenzo
The price is NZ$122
28 Feb - 1 Mar
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (213 reviews)
  • cleanliness
    Experience the city from a rooftop terrace at this luxurious Santa Cruz hotel.
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is NZ$190
27 Feb - 28 Feb
Marriott Santa Cruz de la Sierra Hotel

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124 reviews)
  • cleanliness
    Experience wellness at a spa hotel in Santa Cruz with massages and outdoor pool.
"The staff and property are second to none! "
United States
Cynthia
The price is NZ$193
20 Feb - 21 Feb
Hotel Cortez

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (88 reviews)
  • cleanliness
    Comfortable city hotel with free parking and convenient access to Santa Cruz.
"Amazing breakfast "
United States
Sergio
The price is NZ$82
2 Mar - 3 Mar
Ibis Santa Cruz DE LA Sierra

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (84 reviews)
  • cleanliness
    Modern aparthotel in Santa Cruz with outdoor pool and fitness centre nearby.
"Good price, great hotel!"
United States
James
The price is NZ$65
2 Mar - 3 Mar
Premium Suites Deluxe Aparthotel Equipetrol

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
  • cleanliness
    Modern apartments with kitchens and balconies in Santa Cruz's vibrant district.
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (43 reviews)
  • cleanliness
    Experience rejuvenation at this spa hotel near Santa Cruz's cultural landmarks.
"Room was great and staff were very accommodating!"
Canada
David
The price is NZ$77
19 Feb - 20 Feb
HOTEL OSHO

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (418 reviews)
  • cleanliness
    Relax in sophisticated style near popular Santa Cruz attractions and dual pools.
"Rooms were very clean and service was excellent "
United States
JESUS
The price is NZ$209
15 Mar - 16 Mar
Camino Real Hotel

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105 reviews)
  • cleanliness
    Stylish Santa Cruz hotel offers convenient access to shopping and city attractions.
"Excelente Hotel "
Mexico
JACOB
Hotel G

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (284 reviews)
  • cleanliness
    Explore Santa Cruz's entertainment district from this well-connected hotel.
"Awesome hotel "
Canada
John
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (202 reviews)
  • cleanliness
    Walk the colourful streets of Santa Cruz from this well-positioned hotel in Equipetrol.
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (90 reviews)
  • cleanliness
    Scenic aparthotel in Santa Cruz with outdoor pool and premium comforts.
"Easy to access"
United States
Dorothy
The price is NZ$77
2 Mar - 3 Mar
Terranova Suites

Hotel BY Armonia SCZ

Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very good, (7 reviews)
  • cleanliness
    Enjoy a revitalising escape in Santa Cruz with an outdoor pool and colonial ambiance.
"Very beautiful grounds. They were very responsive and accommodating. I enjoyed the hotel very much. "
United States
Kaerlig
Hotel BY Armonia SCZ

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
  • cleanliness
    Explore this Santa Cruz retreat with pool and convenient city access.
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is NZ$104
2 Mar - 3 Mar
Hotel Continental Park

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
  • cleanliness
    Relaxing retreat with pool and spa services in Santa Cruz.
"Very comfortable and quiet place and very good location. "
United States
Luis
Apart Hotel Toborochi

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (12 reviews)
  • cleanliness
    Stay cosy in Santa Cruz at a hotel with free breakfast and convenient kitchenettes.
"Perfect hotel"
Turkey
Yener
The price is NZ$91
20 Mar - 21 Mar
Equipetrol Suites Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Our guide on where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

More cheap accommodation in Santa Cruz

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Vibrant Local Culture: Experience the rich heritage of Santa Cruz through its lively atmosphere, traditional architecture, and friendly locals.
  • Outdoor Adventures: Explore serene lakes and parks perfect for family outings and outdoor activities.
  • Diverse Culinary Scene: Indulge in a variety of culinary delights at local restaurants, showcasing unique Bolivian flavours.
  • Family-Friendly Attractions: Discover attractions like the piazza and cathedral that cater to families and tourists alike.
  • Variety of Accommodations: Enjoy a range of lodging options, from family-friendly hotels to unique hostels, ensuring a comfortable stay.

Find great hotels in Santa Cruz

Experience the vibrant charm of Santa Cruz, Bolivia, with a range of accommodation options tailored to suit every traveller. From family-friendly hotels to pet-friendly havens and business-focused facilities, Santa Cruz offers diverse lodging types to meet your needs. Discover the best hotels, star-rated options, and unique hostels that promise a comfortable stay while exploring this lively city.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Nestled in the heart of Santa Cruz, Los Tajibos offers a delightful blend of luxury and relaxation, ideal for business and family travellers. This 3.5-star hotel features a comprehensive business centre, including meeting rooms and conference spaces, making it perfect for corporate guests. Families will appreciate the child-friendly amenities, such as a children's pool and a first aid kit. For those seeking a rejuvenating experience, the full-service spa provides a range of treatments, ensuring a tranquil escape during your stay.
  • Hotel G: Emphasising a pet-friendly philosophy, Hotel G is a charming 3.5-star accommodation that welcomes furry companions. Perfect for travellers who wish to bring their pets along, the hotel has a clear pet policy, allowing dogs and cats with certain conditions. Located in the vibrant Santa Cruz area, this hotel maintains a welcoming atmosphere that caters to pet owners, ensuring that you and your four-legged friends enjoy a comfortable and enjoyable stay.
  • Hampton by Hilton Santa Cruz/Equipetrol, Bolivia: This 4.5-star gem is ideal for families and LGBTQIA travellers seeking a luxurious experience in Santa Cruz. The hotel is committed to inclusivity, featuring amenities tailored for families, including babysitting services and complimentary cribs. With a stylish décor and modern facilities, guests can relax in comfort while enjoying the hotel's thoughtful services. Its location also provides easy access to local attractions, making it a fantastic choice for those looking to explore the city.

Where to stay in and around Santa Cruz

Santa Cruz, Bolivia, offers a vibrant blend of traditional Spanish architecture and modern charm, making it an ideal destination for family getaways and outdoor adventures. Explore the serene lakes surrounding the city and immerse yourself in the friendly atmosphere of Santa Cruz de la Sierra. With its rich excursions and unique neighbourhoods, you’ll find the perfect spots to relax and experience the local culture during your unforgettable holiday.

  • Warnes: Located 30.6km from Santa Cruz, Warnes is a vibrant city that offers a unique blend of family-friendly activities and business opportunities. The town sees a steady influx of visitors year-round, with peak times in September and the festive season from December to January. Here, you can indulge in shopping at local centres and malls or unwind at a nearby resort. Notable attractions include charming local churches and a beautiful botanical garden, perfect for a leisurely stroll amidst nature.
  • Colinas del Urubo: Nestled within the Santa Cruz area, Colinas del Urubo is a quaint village that attracts families and outdoor enthusiasts alike. With visitor numbers peaking in March and during the September to October period, this village offers a serene escape. The main highlight is the resort, which provides a perfect base for exploring the stunning natural surroundings. The local botanical garden is a must-visit, showcasing the region's diverse flora.
  • La Guardia: Just 20.9km from Santa Cruz, La Guardia is a city that promises an adventurous experience. It attracts visitors throughout the year, with peaks in September and the holiday season. Families and thrill-seekers can enjoy various activities at local resorts, while the enchanting botanical garden, picturesque waterfall, and lively piazza square provide ample opportunities for exploration and relaxation. La Guardia combines the excitement of adventure with the charm of family-friendly experiences.

Things to do in Santa Cruz

Santa Cruz offers a vibrant mix of activities perfect for families and outdoor enthusiasts alike. Enjoy a stay at a resort, explore local shopping centres, and indulge in the diverse culinary delights at various restaurants. With its lively atmosphere, Santa Cruz invites you to discover its unique attractions while embracing the city's rich culture and hospitality.

Shopping

In Santa Cruz, you can shop at Ventura Mall, a vibrant shopping centre with entertainment and family vibes. La Recova Artisan Walk offers a charming market experience for unique souvenirs. If you're up for a drive, visit Patio Design LifeStyle Center, known for its stylish shopping atmosphere.

Recreation

At Ramon Tahuichi Aguilera Stadium, immerse yourself in the lively sports atmosphere while participating in fitness classes and outdoor activities. The vibrant energy of the stadium makes it an ideal spot for both relaxation and recreation, allowing you to enjoy the spirit of Santa Cruz.

Adventure

In Santa Cruz, explore the stunning Amboró National Park, where you can hike through lush forests and spot unique wildlife. Experience the thrill of zip-lining at Parque Lomas de Arena, soaring over sand dunes, or take a river rafting adventure on the Piraí River for an adrenaline rush.

Nightlife

In Santa Cruz, the Cine Center offers a romantic cinema experience perfect for a laid-back night out. For a cultural touch, head to Casa Municipal de Cultura Raúl Otero Reiche, where theatre performances create a vibrant atmosphere ideal for families and couples alike.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, visit during the cheaper months of June, August, or November, and aim to book your stay for Saturday, the least expensive day. Utilize Expedia’s search tool to find budget-friendly accommodation, sorting by price and filtering for eco-certified options. Consider bundling your hotel with flights and activities for additional savings. Explore free attractions and use local public transport to keep costs down while enjoying the vibrant culture of Santa Cruz.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are June, August and November, where the prices are slightly lower. This is in comparison to March to April and September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Expedia's search tool gives you the flexibility to choose your budget, desired location, and additional preferences. You can easily sort your results by price, starting with the most affordable options first. Additionally, you have the ability to refine your search by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodation choices available for booking.
  • Consider bundling your trip: You can save some money by combining your Santa Cruz hotel booking with your flights and activities through an Expedia package.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for a city-themed, family, or outdoor holiday, offering a rich mix of cultural and recreational experiences. Visitors can explore key attractions such as the piazza, cathedral, and various landmarks that showcase the city's vibrant heritage. The diverse points of interest cater to those seeking family-friendly activities and outdoor adventures, making Santa Cruz an ideal destination for all types of travellers.

  • Plaza 24 de Septiembre: This vibrant square is the heart of Santa Cruz, offering a lively atmosphere filled with local culture. Surrounded by cafés and shops, it's a perfect spot to relax and soak in the city's energy while watching street performers and locals go about their day.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, San Lorenzo Cathedral is a peaceful retreat showcasing intricate designs and religious art. Visitors can appreciate the spiritual vibe and historical significance while exploring its serene interior.
  • Blacutt Square: Known for its picturesque gardens and fountains, Blacutt Square is ideal for leisurely strolls and excursions. This landmark offers a tranquil escape with walking paths and spaces for picnics, making it a favourite among locals and tourists alike.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are slightly low and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly HighAverage
February77.0°F (25.0°C)Light RainMostly CloudyAverageAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnySlightly HighAverage
August72.9°F (22.7°C)No RainSunnyAverageSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnySlightly LowAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageSlightly Low
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

The nearest major airports for your trip to Santa Cruz

When flying into Santa Cruz, Bolivia, the major airport to consider is Viru Viru International Airport (VVI), situated approximately 16.1km from the city centre. Nearby, you'll find several excellent hotel options, including the 5-star Marriott Santa Cruz de la Sierra Hotel and Radisson Hotel Santa Cruz, both about 14.5km from the airport. The Novotel Santa Cruz De La Sierra, also a 5-star establishment, is located 17.7km away. These hotels offer convenient access to the airport, ensuring a smooth transition to your accommodation upon arrival.

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a favourite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. Some other homes for rent in Santa Cruz include Jose Luis Noya and Cozy and independent. Downtown house JH.. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Urubo Suite - Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
HOTEL OSHO is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 286 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Guarani Nandereko Nomai Art and Culture Center and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Arenal Park and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.