Santa Ana Travel Guide

Tourist Guide

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can browse for the perfect souvenirs at El Machetazo Santa Ana during your visit to Panama City. Amble around the area's parks or visit its shops.
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Activities

Panama Canal Tour: Miraflores Locks & IMAX Movie - Afternoon

Panama Canal Round-trip: Miraflores Locks & IMAX in English

NZ$33
per adult
100% of travellers recommend
Panama Canal Round-trip: Miraflores Locks & IMAX in English
Panama Canal Half Transit Experience

Panama Canal Partial Transit

NZ$259
per adult
86% of travellers recommend
Panama Canal Partial Transit
Panama City: POIN Swing Experience

Panama City: POIN Swing Experience

NZ$56
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
Half day of Panama city and canal tour: shared and private

Half day of Panama city and canal tour: shared and private

NZ$115
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

NZ$72
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

NZ$268
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
See all activities in Panama City

Our pick of the best Santa Ana Hotel Deals

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is NZ$177 per night from 13 Aug to 14 Aug
NZ$177
13 Aug - 14 Aug
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (103 reviews)
"Amazing location and comfort"

Reviewed on 8 Aug 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is NZ$246 per night from 1 Sept to 2 Sept
NZ$246
1 Sept - 2 Sept
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,816 reviews)
"Todo estuvo excelente nos atendieron bien"

Reviewed on 10 Aug 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is NZ$263 per night from 6 Sept to 7 Sept
NZ$263
6 Sept - 7 Sept
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,658 reviews)
"Perfect for a night in Panama. near to the airport"

Reviewed on 10 Aug 2026

Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
The price is NZ$342 per night from 9 Sept to 10 Sept
NZ$342
9 Sept - 10 Sept
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
Central Hotel Panama Casco Viejo
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is NZ$462 per night from 23 Aug to 24 Aug
NZ$462
23 Aug - 24 Aug
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
Dreams Playa Bonita Panama - All Inclusive
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is NZ$366 per night from 28 Aug to 29 Aug
NZ$366
28 Aug - 29 Aug
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
Megapolis Hotel Panamá
See all 1,813 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Santa Ana Travel Guide

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