Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Fuerte Amador Resort & Marina
Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.
Miraflores Locks
Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the casinos and shops in this vibrant area.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.
Activities
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama City: Poin Full Package Experience
Day Tour in San Blas Islands All Included Visiting 4 Islands
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Our pick of the best Santa Ana Hotel Deals
Casco View Apartments
Room was clean large and great to have kitchen and laundry in the unit. The pool is small and not really a lounging area. Overall it was super loud, dogs barking, alarms going off and immediate area a little sketch
Reviewed on 27 Oct 2025
Hotel Riu Plaza Panama
Yes breakfast menu was fresh. Staff courteous, did not
Reviewed on 5 Dec 2025
Crowne Plaza Panama Airport by IHG
Had a short overnight stop in our way back to the US. Rooms were clean and quiet. Staff was very helpful.
Reviewed on 9 Dec 2025
Las Americas Golden Tower Panama
$304 for 3 nights I was nervous. But it surprised me. It was a very clean, convenient and way more than I expected. I would definitely return.
Reviewed on 2 Dec 2025
Megapolis Hotel Panamá
Lovely staff, close to everything, super comfy room for the price. 10/10!
Reviewed on 8 Dec 2025
Waldorf Astoria Panama
I loved everything about my stay
Reviewed on 29 Nov 2025
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Ancon Hill are some notable places to visit nearby.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Ancon Hill are a few top places to visit.