Popular places to visit

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Fuerte Amador Resort & Marina
Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Miraflores Locks
Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.
Activities

Panama City Visit an Indian town Embera and waterfall with lunch

Panama City: Poin Full Package Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

Boat tour in the Panama Canal to Monkeys and sloths islands

Panama City: Poin Glass Observation Deck Ticket with VR Tour

The Panama Barcrawl - The OG Crawl (Panama City, Panama)
Our pick of the best Santa Ana Hotel Deals

Casco View Apartments
Great stay, would recommend.
Reviewed on 4 Sept 2025

Hotel Riu Plaza Panama
Great location, and friendly staff.
Reviewed on 18 Oct 2025

Crowne Plaza Panama Airport by IHG
The restaurant was very clean staff helpful but bellboy didn’t return key card. Nobody answered phone when I called operator or front desk
Reviewed on 17 Oct 2025

Dreams Playa Bonita Panama - All Inclusive
Very nice
Reviewed on 6 Oct 2025

Megapolis Hotel Panamá
Relaxing
Reviewed on 16 Oct 2025

Marriott Panama Hotel
Helpfull staff
Reviewed on 3 Oct 2025
Other neighbourhoods around Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

San Felipe
While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and National Theater.

El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Ancon Hill are some notable places to visit nearby.

Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.