Sanctuary Hotels, Sanibel

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Check prices for these dates

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

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Our top choices for Sanctuary hotels

Marina
MALU LANI Inn & Marina

MALU LANI Inn & Marina

MALU LANI Inn & Marina
2.5 star property
24.7 km from Sanctuary
The price is NZ$575
includes taxes & fees
28 Dec - 29 Dec
MALU LANI Inn & Marina
Suite with King Bed, Beachfront, Balcony | Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1047)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is NZ$288
includes taxes & fees
6 Jan - 7 Jan 2026
Lani Kai Beachfront Resort
Outdoor pool, pool loungers
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1004)
"Great hotel and location and good value. "
United States
Amy
The price is NZ$241
includes taxes & fees
2 Jan - 3 Jan 2026
Doubletree by Hilton Fort Myers at Bell Tower Shops
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1004)
"Spotless rooms , great breakfast , courteous staff ! Had a great time !"
United States
Arijit
The price is NZ$262
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.6 out of 10, Excellent, (1000)
"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "
United States
Aleksandar
The price is NZ$213
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Garden Inn Ft Myers
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1492)
"Excellent value with a great location and a solid staff!"
United States
David
The price is NZ$498
includes taxes & fees
7 Jan - 8 Jan 2026
Sanibel Island Beach Resort
Lobby lounge
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (794)
"A great location. Staff was very helpful. Pool was heated!"
United States
FRED
The price is NZ$204
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Terrace/patio
Dolphin Key Resort

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1214)
"Nice rooms, great having the bar onsite"
United States
Lee
The price is NZ$153
includes taxes & fees
29 Dec - 30 Dec
Dolphin Key Resort
Exterior
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
20.4 km from Sanctuary
9.4 out of 10, Exceptional, (1206)
"The staff was exceptional!"
United States
Robert J
The price is NZ$537
includes taxes & fees
11 Jan - 12 Jan 2026
Pink Shell Beach Resort and Marina
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1000)
"The property was clean and the breakfast was excellent the staff was friendly and convenient to Sanibel Island"
United States
robert
The price is NZ$258
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott Fort Myers Sanibel
2 outdoor pools
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
21.5 km from Sanctuary
8.6 out of 10, Excellent, (1583)
"Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach"
United States
Erika
The Lighthouse Resort Inn & Suites
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
21.5 km from Sanctuary
8.8 out of 10, Excellent, (1002)
"Great Place to Stay!"
United States
JUDY
The price is NZ$370
includes taxes & fees
28 Dec - 29 Dec
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.6 out of 10, Excellent, (1002)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is NZ$233
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.4 out of 10, Exceptional, (1089)
"Is great place to stay."
United States
Anastassia
The price is NZ$252
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Interior entrance
Allure Suites

Allure Suites

Allure Suites
3.0 star property
27.2 km from Sanctuary
7.6 out of 10, Good, (1003)
"Room was spotless, front desk gentleman was very polite"
United States
Eric
The price is NZ$170
includes taxes & fees
29 Dec - 30 Dec
Allure Suites
Outdoor pool, open 8:00 AM to 10:00 PM, pool cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1002)
"Clean resort, quiet and very friendly staff! Pools were amazing. "
United States
Jenny
The price is NZ$453
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Cape Coral Resort At Marina Village
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.0 out of 10, Very good, (1006)
"Nice pool area and hot tub. Nice breakfast and staff were polite and friendly. "
United Kingdom
Dennis
The price is NZ$258
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Outdoor pool, open 7:30 AM to 9:30 PM, free pool cabanas, pool loungers
Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (909)
"This place is wonderful! The staff were extremely friendly and the my room (#9) was spotless. The pool and outdoor lounge were great! They also have a gas fire table that you can use and it looks out over the water. I will definitely stay here again!!! The whole place had a very cute vibe. "
United States
Laurie
Latitude 26 Waterfront Resort & Marina
Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view
Edison Beach House

Edison Beach House

Edison Beach House
3.5 star property
21.2 km from Sanctuary
9.4 out of 10, Exceptional, (1593)
"Awesome stay "
United States
mary
The price is NZ$403
includes taxes & fees
1 Jan - 2 Jan 2026
Edison Beach House
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1004)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is NZ$652
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott Sanibel Harbour Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.
Fort Myers featuring a beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Sea School and Dunes Golf and Tennis Club are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

DiamondHead Beach Resort

DiamondHead Beach Resort

10/10 Excellent
"Absolutely amazing stay! This Diamondhead resort in exceeded our expectations in every way. From the moment we arrived, the staff was welcoming, friendly, and genuinely attentive, making us feel relaxed and taken care of right away. The location is unbeatable, right on the beach with breathtaking views, stunning sunsets, and easy access to the sand and water. Waking up to the sound of the waves and enjoying morning coffee overlooking the Gulf was unforgettable. Our room was spotless, comfortable, and beautifully maintained, with a great view. The resort amenities were top-notch: a gorgeous pool area, clean beach setup, and everything you need for a stress-free vacation. The grounds were well-kept and had a peaceful, tropical feel. Would definitely stay again!"
Anthony 7-night trip
Posted 20 hours ago
DiamondHead Beach Resort

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 12 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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