A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana Hotels, Guayaquil

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Our top choices for Puerto Santa Ana hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Airport transfer and breakfast were great!"
United States
Halima
The price is NZ$188
26 July - 27 July
Wyndham Guayaquil Puerto Santa Ana

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (56 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is NZ$128
6 July - 7 July
River View suites Puerto Santa Ana gye

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is NZ$151
13 July - 14 July
Luxury Suites Riverfront GYE

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (270 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is NZ$115
10 July - 11 July
Hotel Puerto Pacifico Guayaquil Airport

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,004 reviews)
"Great place to stay"
United States
Daniel
The price is NZ$168
11 July - 12 July
Oro Verde Guayaquil

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (641 reviews)
"Great place to stay. Walking distance to airport."
Australia
Ashleigh
The price is NZ$65
6 July - 7 July
DC Suites Aeropuerto

NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is NZ$68
19 July - 20 July
NCG SUITE ATARAZANA

NCG Suite 2

NCG Suite 2
2.0 star property
7.1 km from Puerto Santa Ana
The price is NZ$42
6 July - 7 July
NCG Suite 2

Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place to stay"
United States
Martha Lucia
The price is NZ$141
12 July - 13 July
Grand Hotel Guayaquil, Centro Histórico.

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place"
Canada
Michael
The price is NZ$191
12 July - 13 July
Holiday Inn Guayaquil Airport by IHG

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is NZ$195
9 July - 10 July
Iguanazu Bed & Breakfast

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (703 reviews)
"Good hotel"
United States
juan pablo
The price is NZ$176
12 July - 13 July
Radisson Hotel Guayaquil

Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (939 reviews)
"Excellent service"
United States
Maritza
The price is NZ$117
18 July - 19 July
Hotel Palace Guayaquil

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (107 reviews)
"Nice business hotel for staying when working abroad"
United States
wagner
The price is NZ$161
12 July - 13 July
Doubletree By Hilton Guayaquil

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay, connected to Large Mall with multiple food venue's"
United States
Francis
The price is NZ$167
18 July - 19 July
TRYP by Wyndham Guayaquil Airport

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,000 reviews)
"The room was really clean and the staff in the lobby were really helpful. Breakfast was good"
United States
Rosa
The price is NZ$147
18 July - 19 July
Wyndham Garden Guayaquil

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Great location, very kind staff."
United States
Tomas
The price is NZ$137
19 July - 20 July
Unipark by Oro Verde Hotels

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.8 out of 10, Excellent, (936 reviews)
"Excellent stay highly recommended"
United States
Carol
The price is NZ$194
12 July - 13 July
Hilton Colon Guayaquil

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location!"
United States
Laura
The price is NZ$157
10 July - 11 July
Courtyard by Marriott Guayaquil

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (140 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is NZ$116
6 July - 7 July
Mansión del Río
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most. Learn more about Puerto Santa Ana
Learn more about Puerto Santa Ana

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and La Rotonda while you're in town.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and World Trade Center, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Recent Reviews in Puerto Santa Ana

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 80 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.