Medical Center District Hotels, San Antonio

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
10 Oct - 12 Oct
Next weekend
17 Oct - 19 Oct

Filter by

Guest rating
Guest rating
Star rating

4642 Cheap Hotels in Medical Center District - Specials, Reviews, & Last Minute Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Front of property

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2987)
"Great hotel and clean"
The price is NZ$181
includes taxes & fees
9 Oct - 10 Oct
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
Lobby

San Antonio Marriott Northwest Medical Center

3.5 star property
8.6 out of 10, Excellent, (1007)
"The breakfast was really good. "
The price is NZ$203
includes taxes & fees
10 Oct - 11 Oct
San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Pool

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1007)
"Staff was excellent "
The price is NZ$176
includes taxes & fees
26 Oct - 27 Oct
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1284)
"Friendly staff."
The price is NZ$182
includes taxes & fees
13 Oct - 14 Oct
Drury Inn & Suites San Antonio Northwest Medical Center
Park Inn by Radisson
Reception

Park Inn by Radisson

2.0 star property
7.2 out of 10, Good, (1002)
"Clean room and convenient to my dr's appointment "
The price is NZ$121
includes taxes & fees
7 Nov - 8 Nov
Park Inn by Radisson
Courtyard by Marriott Medical Center San Antonio
Exterior

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.8 out of 10, Excellent, (1003)
"Great front desk service, very clean and spacious room, would definitely book again. "
The price is NZ$171
includes taxes & fees
19 Oct - 20 Oct
Courtyard by Marriott Medical Center San Antonio
SpringHill Suites by Marriott San Antonio Medical Center/NW
Premium bedding, pillow-top beds, in-room safe, desk

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1003)
"Nice hotel"
The price is NZ$184
includes taxes & fees
15 Oct - 16 Oct
SpringHill Suites by Marriott San Antonio Medical Center/NW
Atria Inn & Suites
Front of property

Atria Inn & Suites

2.0 star property
7.4 out of 10, Good, (260)
"Nice and helpful staff "
Atria Inn & Suites
Motel 6 San Antonio, TX - Northwest Medical Center
Free WiFi, bed sheets

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (999)
"Really enjoyed our stay"
The price is NZ$87
includes taxes & fees
9 Oct - 10 Oct
Motel 6 San Antonio, TX - Northwest Medical Center
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Free daily on-the-go breakfast

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1005)
"Easy check in"
The price is NZ$122
includes taxes & fees
15 Oct - 16 Oct
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Studio 6 San Antonio, Tx - Northwest Medical Center
Desk, laptop workspace, blackout curtains, free WiFi

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.2 out of 10, Good, (184)
"Very nice"
The price is NZ$99
includes taxes & fees
17 Oct - 18 Oct
Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, TX - Medical Center
1 bedroom, desk, laptop workspace, free WiFi

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (754)
"The staff is great! Customer service is their forefront!"
The price is NZ$97
includes taxes & fees
19 Oct - 20 Oct
Studio 6 San Antonio, TX - Medical Center
Flex Studios
Basic Room, Multiple Beds, Non Smoking

Flex Studios

2.5 star property
6.0 out of 10, (487)
"heb is nearby. "
The price is NZ$88
includes taxes & fees
15 Oct - 16 Oct
Flex Studios
OYO Inn & Suites Medical Center San Antonio
Exterior

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (218)
"Always great stay"
The price is NZ$126
includes taxes & fees
9 Oct - 10 Oct
OYO Inn & Suites Medical Center San Antonio
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Water park

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 star property
9.0 out of 10, Wonderful, (1105)
"Great family friendly resort"
The price is NZ$234
includes taxes & fees
28 Oct - 29 Oct
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Courtyard by Marriott San Antonio SeaWorld - Westover Hills
Indoor pool, outdoor pool

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

3.0 star property
8.6 out of 10, Excellent, (1010)
"Will stay there again!"
The price is NZ$198
includes taxes & fees
27 Oct - 28 Oct
Courtyard by Marriott San Antonio SeaWorld - Westover Hills
La Quinta Inn & Suites by Wyndham San Antonio Northwest
Exterior

La Quinta Inn & Suites by Wyndham San Antonio Northwest

3.0 star property
8.8 out of 10, Excellent, (1005)
"We have stayed before, and prefer this hotel and location"
The price is NZ$161
includes taxes & fees
12 Oct - 13 Oct
La Quinta Inn & Suites by Wyndham San Antonio Northwest
The Westin San Antonio North
Indoor pool, outdoor pool

The Westin San Antonio North

4.0 star property
8.4 out of 10, Very good, (1113)
"Beautiful hotel! Loved the price "
The price is NZ$178
includes taxes & fees
12 Oct - 13 Oct
The Westin San Antonio North
Days Inn by Wyndham Suites San Antonio North/Stone Oak
Exterior

Days Inn by Wyndham Suites San Antonio North/Stone Oak

2.5 star property
8.0 out of 10, Very good, (1017)
"Nice quiet stay"
The price is NZ$101
includes taxes & fees
12 Oct - 13 Oct
Days Inn by Wyndham Suites San Antonio North/Stone Oak
Menger Hotel
Lobby

Menger Hotel

3.5 star property
9.0 out of 10, Wonderful, (3475)
"One of my favorite historic hotels. "
The price is NZ$204
includes taxes & fees
22 Oct - 23 Oct
Menger Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
Downtown - Riverwalk featuring heritage architecture, boating and a bridge

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Top Medical Center District Hotel Reviews

The Westin San Antonio North

The Westin San Antonio North

10/10 Excellent
"I did not have time for gym. Staff was excellent! I felt safe and comfortable. Love the Starbucks coffee every morning! I have stayed a total of 4 times. That should tell you something! "
Beth 5-night trip
Posted 1 day ago
The Westin San Antonio North

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 119 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.