Visit Medical Center District
Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Room was very neatly clean. Gym is good although one of treadmill does not work. Breakfast is good. Staff: very friendly.
Reviewed on 2 Dec 2025

San Antonio Marriott Northwest Medical Center
Amazing 3 night stay at this beautiful hotel. Beautifully decorated for the holidays. Room was spacious, clean and quiet. Lovely lounge and bar area to catch football games. We will definitely stay here again in the future.
Reviewed on 2 Dec 2025

Courtyard by Marriott Medical Center San Antonio
Room was clean, staff was very friendly!!
Reviewed on 19 Nov 2025

Hotel Valencia Riverwalk
Room
Reviewed on 29 Nov 2025

Riverwalk Plaza
I enjyed the stay, the customer service was welcoming and the location was ideal for our trip.
Reviewed on 29 Nov 2025

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Great atmosphere and space. highly recommend.
Reviewed on 2 Dec 2025
Check Medical Center District hotel availability
Other neighbourhoods around Medical Center District

Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Midtown
Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Tobin Hill
Tobin Hill might not have many top sights, but San Antonio Museum of Art and Historic Brackenridge Golf Course are two attractions nearby that you can check out.

Uptown
If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Alamo Heights
You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Harry B Orem Stadium.

