Visit Medical Center District
Popular places to visit
South Texas Medical Center
If South Texas Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
USAA Corporate Office Headquarters
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
University of Texas Health and Science Center at San Antonio
If University of Texas Health and Science Center at San Antonio is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
CHRISTUS Santa Rosa Hospital - Medical Center
If CHRISTUS Santa Rosa Hospital - Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
University Hospital - University Health System
If University Hospital - University Health System is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
Methodist Healthcare
If Methodist Healthcare is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
Activities

San Antonio Zoo Any Day Ticket including ZooLights

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Tower of the Americas Entry Ticket

The Undead: Zombie Apocalypse Escape Room at Extreme Escape

The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
The room was spotless & the people there was so nice, helpful. Im so thankful. I absolutely recommend this place.
Reviewed on 11 Jan 2026

San Antonio Marriott Northwest Medical Center
Nice stay
Reviewed on 13 Jan 2026

Park Inn by Radisson
Clean room and easy check in
Reviewed on 15 Jan 2026

Hotel Valencia Riverwalk
The property is extra nice and I would stay there again. We had a couple of issues with plumbing and the fact that the river on the "River Walk" was empty. It would have been to know.
Reviewed on 16 Jan 2026

Riverwalk Plaza
Great stay. Older hotel but service was good. Hotel was clean.
Reviewed on 12 Jan 2026

Menger Hotel
Our stay at the Menger Hotel was truly lovely! The adornment throughout is beautiful, the service prompt and thorough, and the easy access to the riverwalk and surrounding area was very convenient! We especially loved the servers at breakfast, so personable and kind. I recommend this place 100%!
Reviewed on 12 Jan 2026
Other neighbourhoods around Medical Center District

Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio River or The DoSeum while you're exploring the area.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Tobin Hill
Tobin Hill might not have many top sights, but San Antonio River and San Antonio Museum of Art are two attractions nearby that you can check out.

Uptown
If you're spending some time in Uptown, San Antonio River and Marion Koogler McNay Art Museum are top sights worth seeing.

Alamo Heights
You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Harry B Orem Stadium.


