Top Hotels Near Lewis and Clark Trail Trailhead in St. Louis from NZ$117

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Our top choices for Lewis and Clark Trail Trailhead hotels

Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1007)
"Very good place to stay"
United States
Jasur
The price is NZ$160
includes taxes & fees
1 Jan - 2 Jan 2026
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
8.6 out of 10, Excellent, (847)
"A very nice stay with very pleasant staff"
United States
Clifford
The price is NZ$184
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express St. Louis West - O'Fallon by IHG
Exterior
Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
3.2 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very good, (409)
"Simple excellent place to stay"
United States
Hussam
The price is NZ$234
includes taxes & fees
2 Jan - 3 Jan 2026
Staybridge Suites O'Fallon Chesterfield by IHG
Property amenity
TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
3.0 star property
5.6 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (274)
"Nice"
United States
Maurice
The price is NZ$239
includes taxes & fees
1 Jan - 2 Jan 2026
TownePlace Suites by Marriott St. Louis Chesterfield
Lobby
Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
3.0 star property
3.6 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very good, (454)
"Love the stay great for families!"
United States
jeriece
The price is NZ$241
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott O'Fallon
Lobby sitting area
Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
7.1 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (720)
"Clean room, quiet"
United States
Laura
The price is NZ$191
includes taxes & fees
23 Jan - 24 Jan 2026
Hilton Garden Inn St. Louis/O'Fallon MO
Standard Room, 2 Queen Beds, Non Smoking
Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
6.6 km from Lewis and Clark Trail Trailhead
8.0 out of 10, Very good, (1001)
"Great place to stay"
United States
Dawn
The price is NZ$158
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Chesterfield - St. Louis
Free daily full breakfast
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
10.3 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1004)
"Great hotel!"
United States
Lorelei
The price is NZ$211
includes taxes & fees
8 Jan - 9 Jan 2026
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
BBQ/picnic Area
Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
10.9 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (579)
"Very clean and nice hotel! "
United States
Gina
The price is NZ$231
includes taxes & fees
23 Jan - 24 Jan 2026
Courtyard by Marriott St. Louis Chesterfield
Exterior
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
13.6 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (26)
"Very nice place. Clean room. Staff was excellent. "
United States
Richard
The price is NZ$150
includes taxes & fees
30 Dec - 31 Dec
WoodSpring Suites St Peters-OFallon
Front of property – evening/night
Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
3.5 star property
10.9 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (847)
"It was great, clean, quiet and friendly! "
United States
Lisa
The price is NZ$203
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites St. Louis/Chesterfield
Standard Room, 2 Queen Beds
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
12.5 km from Lewis and Clark Trail Trailhead
6.8 out of 10, (999)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is NZ$134
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Exterior
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
14.8 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1038)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is NZ$258
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis Chesterfield
Breakfast, lunch, dinner served; American cuisine
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
14.9 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1001)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is NZ$244
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Place St. Louis/Chesterfield
Property amenity
Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
12.4 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is NZ$379
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott St. Louis Chesterfield
Property amenity
Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
15 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (1002)
"Great hotel! Clean, friendly staff, wonderful amenities!"
United States
Susan
The price is NZ$217
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites St. Louis St. Peters
Lobby
Relax Inn Saint Charles

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
18.2 km from Lewis and Clark Trail Trailhead
6.6 out of 10, (1006)
"Great place to stay "
United States
Askar
The price is NZ$120
includes taxes & fees
30 Dec - 31 Dec
Relax Inn Saint Charles
Lobby
Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
13.4 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (375)
"Room was very clean and great amenities. Breakfast was decent. Great value"
United States
Marcus
The price is NZ$209
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express & Suites St Peters by IHG
Lobby
Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
13.7 km from Lewis and Clark Trail Trailhead
6.2 out of 10, (1002)
"Room was excellent and clean"
United States
catherine
The price is NZ$127
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham St Peters/St Charles
Lobby
Economy Inn Wentzville

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
16.1 km from Lewis and Clark Trail Trailhead
6.4 out of 10, (511)
"The Building has a nice exterior"
United States
Christopher
The price is NZ$117
includes taxes & fees
30 Dec - 31 Dec
Economy Inn Wentzville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lewis and Clark Trail Trailhead Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"Always wonderful! Clean and friendly!"
Michael 3-night trip
Posted 2 days ago
Country Inn & Suites by Radisson, St. Charles Historic District

Hotels near other Lewis and Clark Trail Trailhead attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
9-11 memorial in New York

9-11 Memorial

3.9/5 (30 reviews)
Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?
Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 28 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Lewis and Clark Trail Trailhead?
The Wildwood Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. You'll find it 9.1 mi (14.7 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Drury Plaza Hotel St. Louis Chesterfield and Sonesta ES Suites St. Louis - Chesterfield.
How many hotels can I expect to find near Lewis and Clark Trail Trailhead?
Expedia has 28 hotels and other accommodation options a few miles from Lewis and Clark Trail Trailhead.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available near Lewis and Clark Trail Trailhead.
What can I see and do near Lewis and Clark Trail Trailhead?
Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Golf Headquarters and Babler State Park are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're out exploring.