Isle of Palms Holidays

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Our guide on where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
Fernandina Beach, Florida, USA Historic Downtown 1958

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Find hotels in Amelia City

Our pick of the best Isle of Palms Hotel Deals

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is NZ$309 per night from 19 June to 20 June
NZ$309
19 June - 20 June
includes taxes & fees
9.4/10 Exceptional! (528 reviews)
"An amazing property, with very comfortable room and helpful staff. Complimentary breakfast is great!"

Reviewed on 1 June 2026

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
The price is NZ$357 per night from 9 June to 10 June
NZ$357
9 June - 10 June
includes taxes & fees
9/10 Wonderful! (4,014 reviews)
"The room was not that clean. The staff are never very friendly and for a beach resort you have to pay an additional amount for umbrellas and chairs."

Reviewed on 1 June 2026

Margaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is NZ$348 per night from 4 June to 5 June
NZ$348
4 June - 5 June
includes taxes & fees
9/10 Wonderful! (1,629 reviews)
"Quite a few unexpected fees but overall a nice stay"

Reviewed on 1 June 2026

Hyatt Regency Jacksonville
See all 3,364 properties in Isle of Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Isle of Palms holiday package cost?
Starting from as low as , you can build your own Isle of Palms holiday package. Simply bundle flights, hotels and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Isle of Palms?
If you love getting a great deal, bundle your bookings into an Isle of Palms holiday package. Whether you need hotels, flights, day tours or rental cars, you can book them all in one place. You'll have ample choice at your fingertips too. Expedia has over 550 air carriers and 1 000 000 hotels all over the world to take your pick of. Fly with who you prefer, stay wherever you like and save precious money — now that's the ideal escape!
Where should I stay in Isle of Palms?
Make sightseeing a breeze by staying someplace right around the corner from Isle of Palms's big attractions. St. Johns Town Centre and University of North Florida are two traveller favourites.
What are the top hotels in Isle of Palms?
Get your trip off to a great start by locking in a room at The Retreat Close To Mayo Clinic. It's one of most sought-after hotels in Isle of Palms. Another top option is Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How far in advance should I book my Isle of Palms holiday?
Your best bet is to book early. Airlines usually advertise flights nearly 12 months prior to departure, and this is a perfect opportunity to land some of the lowest prices. Boss just told you to take your holiday time next week? No sweat. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Isle of Palms travel package include?
From hotels and flights to car rentals, Expedia can help you shape an Isle of Palms package that's perfect for you. Holidaying for a while? Look into a rental car, flight and hotel bundle. If you can only squeeze in a quick getaway, a hotel and airfare deal could suit you better. Experiences can also be added once you've made your booking. Our holiday packages make it a breeze to save and plan.
What should I know before booking an Isle of Palms travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your adventure. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever sort of holiday you're planning, there's sure to be a package that matches your budget.
Can I choose my airline with an Isle of Palms Expedia holiday package?
Yes, the choice is all yours. We have access to over 550 partner airlines throughout the world, so you can design your Isle of Palms trip according to your travel needs.
If I'm not able to travel, can I cancel my Isle of Palms holiday package?
Because we understand life is full of surprises, the answer is yes. To find out more, check out our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to cancel or change it with no penalties. Your airline, hotel or car rental company may charge a fee if your booking is older than that.

Discover the most popular places to visit in Isle of Palms

Aerial photo sports stadiums Downtown Jacksonville FL

VyStar Veterans Memorial Arena

Catch an event at VyStar Veterans Memorial Arena during your trip to Jacksonville. Amble around this family-friendly area's riverfront or experience its lively festivals.

VyStar Veterans Memorial Arena
Jacksonville Beach Pier

Jacksonville Beach Pier

Stroll along this charming fishing pier that extends into the Atlantic Ocean. Enjoy the tranquil surroundings in your pursuit of a big catch.

Jacksonville Beach Pier
Jacksonville_DailysPlace_553248633876108217_05

Daily's Place

You can make plans for a show at Daily's Place on your trip to Jacksonville. Amble around this vibrant area's riverfront or experience its lively festivals.

Daily's Place

Activities

Airboat Adventure in Saint Augustine with a Guide

Airboat Adventure in Saint Augustine with a Guide

NZ$134
per adult
100% of travellers recommend
Airboat Adventure in Saint Augustine with a Guide
Gummy Making Class

Gummy Making Class

NZ$34
per traveller
Gummy Making Class
Amelia Island Guided Kayak Tour of Lofton Creek

Amelia Island Guided Kayak Tour of Lofton Creek

NZ$109
per adult
100% of travellers recommend
Amelia Island Guided Kayak Tour of Lofton Creek
See all activities in Jacksonville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.