Large rocks and a sandy beach with sparse vegetation.

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Check prices for these dates

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Isla Santa María hotels

1. Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
Puerto Ayora
United States
David
NZ$502
3 Nov - 4 Nov
Angermeyer Waterfront Inn

2. Hotel Fiesta

Hotel Fiesta
Puerto Ayora
United States
Dayana Cristina
NZ$281
14 Oct - 15 Oct
Hotel Fiesta

3. Hotel Ninfa

Hotel Ninfa
Puerto Ayora
United Kingdom
Andrew
NZ$271
13 Oct - 14 Oct
Hotel Ninfa

4. Hotel el descanso del Guia

Hotel el descanso del Guia
Puerto Ayora
United States
marcilene
NZ$130
29 Oct - 30 Oct
Hotel el descanso del Guia

5. El Barranco Galapagos

El Barranco Galapagos
Puerto Ayora
United States
Gloria
NZ$404
13 Oct - 14 Oct
El Barranco Galapagos

6. HOTEL CROSSMAN

HOTEL CROSSMAN
Puerto Ayora
Canada
PENGFEI
NZ$117
17 Oct - 18 Oct
HOTEL CROSSMAN

7. Capitan Max B&B

Capitan Max B&B
Puerto Ayora
United States
Randall Jay
NZ$137
13 Oct - 14 Oct
Capitan Max B&B

8. Hotel La Casa de Judy

Hotel La Casa de Judy
Puerto Ayora
Canada
Alexandra
NZ$155
14 Oct - 15 Oct
Hotel La Casa de Judy

9. Hostal Suenos Silvestres

Hostal Suenos Silvestres
Puerto Ayora
Japan
Shunsuke
NZ$96
15 Oct - 16 Oct
Hostal Suenos Silvestres

10. Maidith Galapagos Inn

Maidith Galapagos Inn
Puerto Ayora
United Kingdom
Thomas
NZ$208
17 Oct - 18 Oct
Maidith Galapagos Inn

11. White House Galapagos

White House Galapagos
Puerto Ayora
United States
Yamile
NZ$94
28 Oct - 29 Oct
White House Galapagos

12. Hotel Santa Fe

Hotel Santa Fe
Puerto Ayora
United States
Michelle
NZ$379
16 Oct - 17 Oct
Hotel Santa Fe

13. Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
Puerto Ayora
United States
TAKUHIRO
NZ$169
14 Oct - 15 Oct
Fernandina Hotel & Spa Galápagos

14. Hotel Galapagos Tortuga Bay

Hotel Galapagos Tortuga Bay
Bella Vista
United States
Isabella
NZ$265
18 Oct - 19 Oct
Hotel Galapagos Tortuga Bay

15. Hotel Cucuve

Hotel Cucuve
Puerto Ayora
United States
Sylvia
NZ$361
15 Oct - 16 Oct
Hotel Cucuve

16. Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
Puerto Ayora
United States
Conrad
NZ$1,022
14 Oct - 15 Oct
Finch Bay Galapagos Hotel

17. Ikala Galapagos Hotel

Ikala Galapagos Hotel
Puerto Ayora
United States
Manoussos
NZ$466
12 Nov - 13 Nov
Ikala Galapagos Hotel

18. Galapagos Verde Azul

Galapagos Verde Azul
Puerto Ayora
Canada
sierra
NZ$141
22 Oct - 23 Oct
Galapagos Verde Azul

19. Galapagos Dreams

Galapagos Dreams
Puerto Ayora
United States
Robert
NZ$154
10 Nov - 11 Nov
Galapagos Dreams

20. Suymar Ecolodge Galapagos

Suymar Ecolodge Galapagos
Bella Vista
Canada
Carole
NZ$197
13 Oct - 14 Oct
Suymar Ecolodge Galapagos
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Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
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Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
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Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

See all hotels in Isla Santa María
A beach with sea lions resting on the sand and a cruise ship in the distance.
Photo by Delen Wong

Top Isla Santa María Hotel Reviews

Recent Reviews in Isla Santa María

Hotel Coloma Galapagos

Hotel Coloma Galapagos

10/10 Excellent
"We had the best time in Galapagos and one of them was the hotel. The 2 ladies in reception were excellent extremely helpful and so kind. Very safe place, the breakfasts are stunning, we were able to try at least one day bc the other we had a early tours. The location is perfect bc it is at the Main Street. It guides you directly to the malecón with less than the 10 min walk. Overall amazing super clean and perfect for overnight we stay 3 nights and not complain at all."
Marco Antonio Pizarro 3-night trip
Posted 18 hours ago
Hotel Coloma Galapagos
Hotel Ninfa

Hotel Ninfa

10/10 Excellent
"All you need for a comfortable stay within in between your day tours. Breakfast is simple , but has everything you need and a very nice people. It is overall cosy. Kept my luggage while we traveled light for a 3 day trip to Isabela"
Miguel 6-night trip
Posted 19 hours ago
Hotel Ninfa
Posada del Mar

Posada del Mar

10/10 Excellent
"Personal amable, instalaciones limpias. Cerca del muelle y de tiendas y restaurantes."
Gabriela 2-night trip
Posted 19 hours ago
Posada del Mar
Hotel el descanso del Guia

Hotel el descanso del Guia

10/10 Excellent
"Espectacular la atención de los recepcionistas, del personal de limpieza y de la persona que atiende en el restaurante. Muchísimas gracias por todo"
Benjamin 1-night trip
Posted 2 days ago
Hotel el descanso del Guia
El Barranco Galapagos

El Barranco Galapagos

10/10 Excellent
"Best ever in Galapagos!! Definitely returning!! Staff awesome!!! The Dock House beautiful!!!"
Yanira 3-night trip
Posted 4 days ago
El Barranco Galapagos
Ikala Galapagos Hotel

Ikala Galapagos Hotel

10/10 Excellent
"great stay at Ikala"
Manoussos 3-night trip
Posted 4 days ago
Ikala Galapagos Hotel
Maidith Galapagos Inn

Maidith Galapagos Inn

10/10 Excellent
"El Servicio es excelentem"
Marisela 2-night trip
Posted 7 days ago
Maidith Galapagos Inn
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

10/10 Excellent
"Staff was very helpful, professional and attentive. Outstanding facility and infrastructure anchored with history and legacy of Gus Angermeyer."
Tobin 4-night trip
Posted 3 weeks ago
Angermeyer Waterfront Inn
Galapagos Verde Azul

Galapagos Verde Azul

10/10 Excellent
"La amabilidad y calidez del personal. Entrada y salida independiente. Habitación amplia, limpia y cómoda. La ubicación es excelente, cerca de todo."
Catalina 5-night trip
Posted 1 month ago
Galapagos Verde Azul

More cheap accommodation in Isla Santa María

Carpao Lodge

Carpao Lodge

18 de febrero e isla floreana Puerto Ayora Islas Galápagos
NZ$49
17 Oct - 18 Oct
7/10 Good! (2 reviews)
Carpao Lodge
Hostal Costa del Pacifico

Hostal Costa del Pacifico

Avenida Tomas de Berlanga S/N Puerto Ayora Galapagos Islands
NZ$77
13 Oct - 14 Oct
Hostal Costa del Pacifico
Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

General Rodriguez Puerto Ayora
NZ$87
13 Oct - 14 Oct
7.6/10 Good! (82 reviews)
Hotel Brisas Del Pacifico
Hostal Sir Francis Drake

Hostal Sir Francis Drake

Av. Baltra y Charles Binford Puerto Ayora Galapagos
NZ$112
13 Oct - 14 Oct
7.4/10 Good! (79 reviews)
Hostal Sir Francis Drake
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos
NZ$355
24 Oct - 25 Oct
Acacia Galapagos Boutique Hotel
El Barranco Galapagos

El Barranco Galapagos

Los colonos Puerto Ayora Galapagos
NZ$409
25 Oct - 26 Oct
9.8/10 Exceptional! (98 reviews)
El Barranco Galapagos

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Finch Bay Galapagos Hotel and Maidith Galapagos Inn. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best holiday rentals that Isla Santa María has to offer?
Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travellers to Isla Santa María will find plenty to explore and enjoy. There are 216 hotels and other accommodation options in the larger region. Find out more about Isla Santa María.
What is there to see in Isla Santa María?
Favourite places to visit include Galápagos National Park, Post Office Bay and Punta Suarez. Take a look at what more there is to see and do in Expedia's Isla Santa María guide.
What's the seasonal weather in Isla Santa María?
The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.